Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andrea Guennoun"'
Autor:
Masato Ogishi, Andrés Augusto Arias, Rui Yang, Ji Eun Han, Peng Zhang, Darawan Rinchai, Joshua Halpern, Jeanette Mulwa, Narelle Keating, Maya Chrabieh, Candice Lainé, Yoann Seeleuthner, Noé Ramírez-Alejo, Nioosha Nekooie-Marnany, Andrea Guennoun, Ingrid Muller-Fleckenstein, Bernhard Fleckenstein, Sara S. Kilic, Yoshiyuki Minegishi, Stephan Ehl, Petra Kaiser-Labusch, Yasemin Kendir-Demirkol, Flore Rozenberg, Abderrahmane Errami, Shen-Ying Zhang, Qian Zhang, Jonathan Bohlen, Quentin Philippot, Anne Puel, Emmanuelle Jouanguy, Zahra Pourmoghaddas, Shahrzad Bakhtiar, Andre M. Willasch, Gerd Horneff, Genevieve Llanora, Lynette P. Shek, Louis Y.A. Chai, Sen Hee Tay, Hamid H. Rahimi, Seyed Alireza Mahdaviani, Serdar Nepesov, Aziz A. Bousfiha, Emine Hafize Erdeniz, Adem Karbuz, Nico Marr, Carmen Navarrete, Mehdi Adeli, Lennart Hammarstrom, Hassan Abolhassani, Nima Parvaneh, Saleh Al Muhsen, Mohammed F. Alosaimi, Fahad Alsohime, Maryam Nourizadeh, Mostafa Moin, Rand Arnaout, Saad Alshareef, Jamila El-Baghdadi, Ferah Genel, Roya Sherkat, Ayça Kiykim, Esra Yücel, Sevgi Keles, Jacinta Bustamante, Laurent Abel, Jean-Laurent Casanova, Stéphanie Boisson-Dupuis
Human cells homozygous for rare loss-of-expression (LOE) TYK2 alleles have impaired, but not abolished, cellular responses to IFN-alpha/beta (underlying viral diseases in the patients) and to IL-12 and IL-23 (underlying mycobacterial diseases). Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b84d9e1175645fc685895f3e5322af7
https://hdl.handle.net/20.500.12511/10166
https://hdl.handle.net/20.500.12511/10166
Autor:
Rui Yang, Rubén Martínez-Barricarte, Janet Markle, Franck Rapaport, Stuart G. Tangye, Mathieu Bourgey, David Langlais, Anne Puel, Aziz Belkadi, Masato Ogishi, Simon J. Pelham, Jean-Laurent Casanova, Bertrand Boisson, Cindy S. Ma, Vivien Béziat, Eman Abou Moussa, Jérémie Rosain, Laurent Abel, Tomi Lazarov, Serkan Belkaya, Fatima Ailal, Ibtihal Benhsaien, Coralie Briand, Alessandro Plebani, Romain Lévy, Frederic Geissmann, Caroline Deswarte, Andrea Guennoun, Luis R. Saraiva, Tanwir Habib, Mehdi Emam, Vassilios Lougaris, Philippe Gros, Yu Jerry Zhou, Ahmed Aziz Bousfiha, Geetha Rao, Kathryn Payne, Sylvain Breton, Ai Ing Lim, Kang Liu, Kunihiko Moriya, Danielle T. Avery, Bénédicte Neven, Nico Marr, Jacinta Bustamante, Mélanie Migaud, James P. Di Santo
Publikováno v:
J Clin Invest
We studied a child with severe viral, bacterial, fungal, and parasitic diseases, who was homozygous for a loss-of-function mutation of REL, encoding c-Rel, which is selectively expressed in lymphoid and myeloid cells. The patient had low frequencies
Autor:
Khalid A. Fakhro, Fatima Al Ali, Mehdi Adeli, Salim Bougarn, Alya Al-Shakaki, Amel Hassan, Debra O. Prosser, Eman Al Maslamani, Rafah Mackeh, Donald R. Love, Amal Al-Naimi, Taushif Khan, Manar Ata, Mohammed Yousuf Karim, Ronald G. Crystal, Bernice Lo, Waleed Aamer, Nico Marr, Khawla Al-Darwish, Ibrahim A. Janahi, Qian Zhang, Amjad Tuffaha, Mahbuba Rahman, Tanwir Habib, Amal Robay, Mohammad Janahi, Andrea Guennoun, Evonne Chin-Smith
Purpose. Human serine/threonine kinase 4 (STK4) deficiency is a rare, autosomal recessive genetic disorder leading to combined immunodeficiency. The extent to which STK4 deficiency impairs immune signaling and host defenses is unclear. We assessed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3596dea6dcb1d51c1d407e757dcb1daf
https://doi.org/10.21203/rs.3.rs-328827/v1
https://doi.org/10.21203/rs.3.rs-328827/v1
Autor:
Marco Ritelli, Harry C. Dietz, Danielle T. Avery, Bertrand Boisson, Soraya Boucherit, Lucie Grodecká, Stuart G. Tangye, Romain Lévy, Kathryn Payne, Tomáš Freiberger, Sophie Cypowyj, Juan Li, Valérie Cormier-Daire, Nicoletta Zoppi, Laurent Abel, Geetha Rao, Vivien Béziat, Andrea Guennoun, Benedetta Bigio, Maya Chrabieh, Salim Bougarn, Marina Colombi, Lei Shang, Emilie Corvilain, Yuval Itan, Anne Puel, Franck Rapaport, Nico Marr, Fransiska Malfait, Delfien Syx, Mélanie Migaud, Tanwir Habib, Sabri Boughorbel, Jean-Laurent Casanova, Cindy S. Ma
Publikováno v:
Science Immunology. 4
Genetic etiologies of chronic mucocutaneous candidiasis (CMC) disrupt human IL-17A/F-dependent immunity at mucosal surfaces, whereas those of connective tissue disorders (CTDs) often impair the TGF-β-dependent homeostasis of connective tissues. The
Autor:
Durga Sivanesan, Cindy S. Ma, Zafer Caliskaner, Katia Abarca, Jaime Inostroza, Hicham Souhi, Nicholas Hernandez, Stephen W. Michnick, Alix Checchi, Tayfun Ozcelik, Ahmed Abid, Rubén Martínez-Barricarte, Noé Ramírez-Alejo, Adil Zegmout, Esra Hazar Sayar, Nico Marr, Ismail Reisli, Lluis Quintana-Murci, Jamila El-Baghdadi, Bernhard Fleckenstein, Hassan Abolhassani, Jacinta Bustamante, Ingrid Müller-Fleckenstein, Ismail Abderahmani Rhorfi, Antonio Condino-Neto, Jose Antonio Tavares de Albuquerque, Rodrigo Naves, Dimitry N. Krementsov, Beatriz Tavares Costa-Carvalho, Sandra Pellegrini, Aurélie Cobat, Robert Fisch, Michael J. Ciancanelli, Gaspard Kerner, Lorena Orozco, Geetha Rao, Jeanette Mulwa, Hans D. Ochs, Stuart G. Tangye, Fabienne Jabot-Hanin, Patricia García, Frederic Geissmann, Stéphanie Boisson-Dupuis, Humberto García-Ortiz, Zhi Li, Tomi Lazarov, Bertrand Boisson, Hicham Naji Amrani, María Elvira Balcells, Caroline Deswarte, Andrea Guennoun, Alexis Strickler, Carolyn C. Jackson, Sevgi Pekcan, Janet Markle, Joshua Halpern, Jean-Laurent Casanova, Cory Teuscher, Che Kang Lim, Anne Puel, Yuval Itan, Lennart Hammarström, Matthieu Bouaziz, Etienne Patin, Laurent Abel, Qian Zhang, Kathryn Payne
Publikováno v:
Science Immunology
Science Immunology, American Association for the Advancement of Science, 2018, 3 (30), pp.eaau8714. ⟨10.1126/sciimmunol.aau8714⟩
Science Immunology, 2018, 3 (30), pp.eaau8714. ⟨10.1126/sciimmunol.aau8714⟩
Science immunology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Science Immunology, American Association for the Advancement of Science, 2018, 3 (30), pp.eaau8714. ⟨10.1126/sciimmunol.aau8714⟩
Science Immunology, 2018, 3 (30), pp.eaau8714. ⟨10.1126/sciimmunol.aau8714⟩
Science immunology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
International audience; Inherited IL-12Rβ1 and TYK2 deficiencies impair both IL-12- and IL-23-dependent IFN-γ immunity and are rare monogenic causes of tuberculosis, each found in less than 1/600,000 individuals. We show that homozygosity for the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faff93666e264a230622ec4489caf311
https://hal-pasteur.archives-ouvertes.fr/pasteur-02070591
https://hal-pasteur.archives-ouvertes.fr/pasteur-02070591
Autor:
Cristina Maccalli, Heba Sidahmed, Davide Bedognetti, Barbara Seliger, Andrea Guennoun, Francesco M. Marincola
When malignant melanoma is diagnosed early, surgical resection is the intervention of choice and is often curative, but many patients present with unresectable disease at later stages. Due to its complex etiology paired with well-documented chemoresi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166b6e0d77671fd3b9afb52429584940
http://hdl.handle.net/11567/996103
http://hdl.handle.net/11567/996103
Autor:
Vladimir Zilberfarb, Melissa Kazantzis, Lotfi Chouchane, Remy Thomas, Konduru S Sastry, Daniel Tews, Mouaadh Abdelkarim, Andrea Guennoun, Martin Wabitsch, Arthur Donny Strosberg
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, BioMed Central, 2015, 13 (1), pp.135. 〈10.1186/s12967-015-0480-6〉
Journal of Translational Medicine, BioMed Central, 2015, 13 (1), pp.135. ⟨10.1186/s12967-015-0480-6⟩
Journal of Translational Medicine, 2015, 13 (1), pp.135. ⟨10.1186/s12967-015-0480-6⟩
Journal of Translational Medicine, BioMed Central, 2015, 13 (1), pp.135. 〈10.1186/s12967-015-0480-6〉
Journal of Translational Medicine, BioMed Central, 2015, 13 (1), pp.135. ⟨10.1186/s12967-015-0480-6⟩
Journal of Translational Medicine, 2015, 13 (1), pp.135. ⟨10.1186/s12967-015-0480-6⟩
Background Functional brown adipose tissue (BAT), involved in energy expenditure, has recently been detected in substantial amounts in adults. Formerly overlooked BAT has now become an attractive anti-obesity target. Methods and results Molecular cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15efe123897eb7f206b685bb3bec9f2
http://www.hal.inserm.fr/inserm-01264507/document
http://www.hal.inserm.fr/inserm-01264507/document
Publikováno v:
Qatar Foundation Annual Research Conference Proceedings Volume 2014 Issue 1.
Background: Recently, the role of autophagy in glucose and lipid metabolism has been emerging. Mice experiments showed that autophagy deficiency could prevent diet-induced obesity, characterized by less fat and a browning phenotype of white adipocyte