Targeting the autosomal Ceratitis capitata transformer gene using Cas9 or dCas9 to masculinize XX individuals without inducing mutations

Autor: Pasquale Primo, Angela Meccariello, Maria Grazia Inghilterra, Andrea Gravina, Giuseppe Del Corsano, Gennaro Volpe, Germano Sollazzo, Serena Aceto, Mark D. Robinson, Marco Salvemini, Giuseppe Saccone

Publikováno v: BMC Genetics, Vol 21, Iss S2, Pp 1-11 (2020)

Abstract Background Females of the Mediterranean fruit fly Ceratitis capitata (Medfly) are major agricultural pests, as they lay eggs into the fruit crops of hundreds of plant species. In Medfly, female sex determination is based on the activation of

Externí odkaz: https://doaj.org/article/35e2600b78a04e8b813ea80973eb002b

Targeting the autosomal Ceratitis capitata transformer gene using Cas9 or dCas9 to masculinize XX individuals without inducing mutations

Autor: Andrea Gravina, Pasquale Primo, Maria Grazia Inghilterra, Germano Sollazzo, Marco Salvemini, Serena Aceto, Mark D. Robinson, Angela Meccariello, Giuseppe Saccone, Gennaro Volpe, Giuseppe Del Corsano

Publikováno v: BMC Genetics
BMC Genetics, Vol 21, Iss S2, Pp 1-11 (2020)

BackgroundFemales of the Mediterranean fruit flyCeratitis capitata(Medfly) are major agricultural pests, as they lay eggs into the fruit crops of hundreds of plant species. In Medfly, female sex determination is based on the activation ofCctransforme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185321e2d081ffa4a5eee9d557a26b53
https://pubmed.ncbi.nlm.nih.gov/33339496

Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests

Autor: Brantley Hall, Zhijian Tu, Stephan Schmeing, Michela Anna Gucciardino, Valeria Petrella, Angela Meccariello, Kostas Bourtzis, Andrea Gravina, Marco Salvemini, Ennio Giordano, Simona Maria Monti, Maryanna Martina Perrotta, Alessia Ruggiero, Javaregowda Nagaraju, Panagiota Koskinioti, Federica Forlenza, František Marec, Pasquale Primo, Maria Eleni Gregoriou, Giuseppe Saccone, Francesca Scolari, Philippos Aris Papathanos, Martina Dalíková, Kostas D. Mathiopoulos, Domenica Ippolito, Mark D. Robinson, Jiannis Ragoussis, Luigi Vitagliano, Kallare P. Arunkumar, Nikolai Windbichler, Konstantina T. Tsoumani

Publikováno v: Science (N. Y., N.Y.) 365 (2019): 1457–+. doi:10.1126/science.aax1318
info:cnr-pdr/source/autori:Meccariello, Angela; Salvemini, Marco; Primo, Pasquale; Hall, Brantley; Koskiniot, Panagiota; Dalikova, Martina; Gravina, Andrea; Gucciar, Michela Anna; Forlenza, Federica; Gregoriou, Maria Eleni; Ippolito, Domenica; Monti, Simona Maria; Petrella, Valeria; Perrotta, Maryanna Martina; Schmeing, Stephan; Ruggiero, Alessia; Scolari, Francesca; Giordano, Ennio; Tsoumani, Konstantina T.; Marec, Frantisek; Windbichler, Nikolai; Nagaraju, Javaregowda; Arunkumar, Kallare P.; Bourtzis, Kostas; Mathiopoulos, Kostas D.; Ragoussis, Jiannis; Vitagliano, Luigi; Tu, Zhijian; Papathanos, Philippos Aris; Robinson, Mark D.; Saccone, Giuseppe/titolo:Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests/doi:10.1126%2Fscience.aax1318/rivista:Science (N. Y., N.Y.)/anno:2019/pagina_da:1457/pagina_a:+/intervallo_pagine:1457–+/volume:365

In insects, rapidly evolving primary sex-determining signals are transduced by a conserved regulatory module producing sex-specific proteins that direct sex determination and sexual differentiation1-4. In the agricultural pestCeratitis capitata(medfl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf736131f7de7cc2e92c42727f3fa020
https://www.zora.uzh.ch/id/eprint/181106/