Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Andrea Grandi"'
Autor:
Davide Buseghin, Andrea Grandi, Erica Ferrini, Gino Villetti, Roberta Ciccimarra, Nicola Sverzellati, Andrea Aliverti, Francesca Pennati, Franco Fabio Stellari
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Idiopathic Pulmonary Fibrosis (IPF), prevalently affecting individuals over 60 years of age, has been mainly studied in young mouse models. The limited efficacy of current treatments underscores the need for animal models that bet
Externí odkaz:
https://doaj.org/article/202c88ebbc6146dc8d65c64f107a171f
Autor:
Martina Buccardi, Andrea Grandi, Erica Ferrini, Davide Buseghin, Gino Villetti, Maurizio Civelli, Nicola Sverzellati, Andrea Aliverti, Francesca Pennati, Franco Fabio Stellari
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Idiopathic Pulmonary Fibrosis (IPF) is a debilitating and fatal lung disease characterized by the excessive formation of scar tissue and decline of lung function. Despite extensive research, only two FDA-approved drugs exist for IPF, with li
Externí odkaz:
https://doaj.org/article/1d01f998850d481ab5eb44d736a8a6c0
Autor:
Martina Buccardi, Erica Ferrini, Francesca Pennati, Elena Vincenzi, Roberta Eufrasia Ledda, Andrea Grandi, Davide Buseghin, Gino Villetti, Nicola Sverzellati, Andrea Aliverti, Franco Fabio Stellari
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Micro-computed tomography (µCT)-based imaging plays a key role in monitoring disease progression and response to candidate drugs in various animal models of human disease, but manual image processing is still highly time-consuming and prone
Externí odkaz:
https://doaj.org/article/f5a183803e474fc89405544c8908d010
Publikováno v:
Veterinary Week; 11/11/2024, p14-14, 1p
Autor:
Martina Mambrini, Laura Mecozzi, Erica Ferrini, Ludovica Leo, Davide Bernardi, Andrea Grandi, Nicola Sverzellati, Livia Ruffini, Mario Silva, Franco Fabio Stellari
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Micro-computed tomography (CT) imaging provides densitometric and functional assessment of lung diseases in animal models, playing a key role either in understanding disease progression or in drug discovery studies. The generation of reliabl
Externí odkaz:
https://doaj.org/article/dd01d3fe6e6948b5b4edccfea9b54f40
Autor:
Francesca Ravanetti, Erica Ferrini, Luisa Ragionieri, Zahra Khalajzeyqami, Maria Nicastro, Yanto Ridwan, Alex Kleinjan, Gino Villetti, Andrea Grandi, Franco Fabio Stellari
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Systemic sclerosis (SSc) is an autoimmune disease characterized by an excessive production and accumulation of collagen in the skin and internal organs often associated with interstitial lung disease (ILD). Its pathogenetic mechanisms are un
Externí odkaz:
https://doaj.org/article/c97189aa45ba426ca1dc74f514bdf894
Autor:
Zahra Khalajzeyqami, Andrea Grandi, Erica Ferrini, Francesca Ravanetti, Ludovica Leo, Martina Mambrini, Luciana Giardino, Gino Villetti, Franco Fabio Stellari
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0270005 (2022)
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with no curative pharmacological treatment. The most used animal model of IPF for anti-fibrotic drug screening is bleomycin (BLM)-induced lung fibrosis. However, several issues have been re
Externí odkaz:
https://doaj.org/article/75a10868de4448b087ae57fe84d962a1
Autor:
Andrea Grandi, Erica Ferrini, Laura Mecozzi, Roberta Ciccimarra, Matteo Zoboli, Ludovica Leo, Zahra Khalajzeyqami, Alex Kleinjan, Clemens W. G. M. Löwik, Gaetano Donofrio, Gino Villetti, Franco Fabio Stellari
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L211-L227
The development of new drugs for idiopathic pulmonary fibrosis strongly relies on preclinical experimentation, which requires the continuous improvement of animal models and integration with in vivo imaging data. Here, we investigated the lung distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a42cdd03823e85eadcd13cfa8b30718b
https://doi.org/10.1152/ajplung.00180.2022
https://doi.org/10.1152/ajplung.00180.2022
Autor:
Andrea Grandi
Publikováno v:
And, Iss 35 (2020)
This thesis project, whose speaker was Prof. Francesca Tosi (Unifi), aims to involve the way makers design applied to a bicycle brand business.
Externí odkaz:
https://doaj.org/article/e412c21426d84f04a4ce87b2170c8ab1
Autor:
Andrea Grandi, Irene Zini, Simone Palese, Carmine Giorgio, Massimiliano Tognolini, Francesco Marchesani, Stefano Bruno, Lisa Flammini, Anna Maria Cantoni, Riccardo Castelli, Alessio Lodola, Antonella Fusari, Elisabetta Barocelli, Simona Bertoni
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Besides their long-known critical role in embryonic growth and in cancer development and progression, erythropoietin-producing hepatocellular carcinoma type B (EphB) receptor tyrosine kinases and their ephrin-B ligands are involved in the modulation
Externí odkaz:
https://doaj.org/article/2fb3581907414d20b981e09761143397