Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrea Glutz"'
Autor:
Marijana Sekulic-Jablanovic, Vesna Petkovic, Matthew B Wright, Krystsina Kucharava, Nathan Huerzeler, Soledad Levano, Yves Brand, Katharina Leitmeyer, Andrea Glutz, Alexander Bausch, Daniel Bodmer
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188596 (2017)
Various insults cause ototoxicity in mammals by increasing oxidative stress leading to apoptosis of auditory hair cells (HCs). The thiazolidinediones (TZDs; e.g., pioglitazone) and fibrate (e.g., fenofibrate) drugs are used for the treatment of diabe
Externí odkaz:
https://doaj.org/article/0bedfaffde8b473f8375b5afaeb10bd7
Autor:
Yves Brand, Vesna Radojevic, Michael Sung, Eric Wei, Cristian Setz, Andrea Glutz, Katharina Leitmeyer, Daniel Bodmer
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108146 (2014)
Hair cells and spiral ganglion neurons of the mammalian auditory system do not regenerate, and their loss leads to irreversible hearing loss. Aminoglycosides induce auditory hair cell death in vitro, and evidence suggests that phosphatidylinositol-3-
Externí odkaz:
https://doaj.org/article/04790f86af7f4085a63dc4770f857e4d
Autor:
Daniel Guido Fuster, Xunde Xian, Vesna Petkovic, Andrea Glutz, Marijana Sekulic-Jablanovic, Giuseppe Albano, Daniel Bodmer, Yves Brand, Joachim Herz, Krystsina Kucharava
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Kucharava, Krystsina; Brand, Yves; Albano, Giuseppe; Sekulic-Jablanovic, Marijana; Glutz, Andrea; Xian, Xunde; Herz, Joachim; Bodmer, Daniel; Fuster, Daniel G.; Petkovic, Vesna (2020). Sodium-hydrogen exchanger 6 (NHE6) deficiency leads to hearing loss, via reduced endosomal signalling through the BDNF/Trk pathway. Scientific reports, 10(1), p. 3609. Springer Nature 10.1038/s41598-020-60262-5
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Kucharava, Krystsina; Brand, Yves; Albano, Giuseppe; Sekulic-Jablanovic, Marijana; Glutz, Andrea; Xian, Xunde; Herz, Joachim; Bodmer, Daniel; Fuster, Daniel G.; Petkovic, Vesna (2020). Sodium-hydrogen exchanger 6 (NHE6) deficiency leads to hearing loss, via reduced endosomal signalling through the BDNF/Trk pathway. Scientific reports, 10(1), p. 3609. Springer Nature 10.1038/s41598-020-60262-5
Acid-base homeostasis is critical for normal growth, development, and hearing function. The sodium–hydrogen exchanger 6 (NHE6), a protein mainly expressed in early and recycling endosomes, plays an important role in regulating organellar pH. Mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46863d5b6f85e621dc295175ecb1c4a4
Autor:
Hossein Ghazavi, Chin Saeng Cho, Dong Sik Chang, Robert J. Stokroos, F Hassepass, Paul Merkus, Masoud Motesadi Zarandi, Thomas Wesarg, David M. Kaylie, Christos Ikonomidis, Cristian Setz, Cas Smits, Armita Kakavand Hamidi, Ho Yun Lee, Myoung Su Choi, Ah-Young Kim, Daniel Bodmer, Andrea Glutz, Sophia E. Kramer, Ingo Todt, Sven Mutze, Elke M. J. Devocht, Mariska Stam, Erwin L. J. George, Mahsa M. Amoli, Joost M. Festen, Alessia Pica, Grit Rademacher, Debara L. Tucci, Philipp Mittmann, Yves Brand, Erin G. Piker, Anneke Spooren, Susan Arndt, Katharina Leitmeyer, A. Miranda L. Janssen, Douglas Garrison, Mohammad Javad Rikhtegar, Druckerei Stückle, Mostafa Qorbani, Jocelyne Bloch, Satz Mengensatzproduktion, Raphael Maire, Nasrin Yazdani, Arneborg Ernst
Publikováno v:
Audiology and Neurotology. 20:CDXVII-CDXXII
Autor:
Cristian Setz, Daniel Bodmer, Andrea Glutz, Katharina Leitmeyer, Leonie Wieland, Yves Brand, Sulamith Egloff
Publikováno v:
BioMed Research International, Vol 2016 (2016)
BioMed Research International
BioMed Research International
Statins are inhibitors of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase, an enzyme necessary for the production of mevalonate. They are widely used as cholesterol-lowering drugs. However, conflicting data about the effect of statins on neuronal
Autor:
Katharina Leitmeyer, Marijana Sekulic-Jablanovic, Nathan Huerzeler, Matthew Blake Wright, Bausch Alexander, Krystsina Kucharava, Daniel Bodmer, Soledad Levano, Andrea Glutz, Vesna Petkovic, Yves Brand
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0188596 (2017)
PLoS ONE, Vol 12, Iss 11, p e0188596 (2017)
Various insults cause ototoxicity in mammals by increasing oxidative stress leading to apoptosis of auditory hair cells (HCs). The thiazolidinediones (TZDs; e.g., pioglitazone) and fibrate (e.g., fenofibrate) drugs are used for the treatment of diabe
Autor:
Vesna Radojevic, Daniel Bodmer, Katharina Leitmeyer, Yves Brand, Cristian Setz, Helen Bumann, Nathan Huerzeler, Andrea Glutz
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
Rapamycin is an antifungal agent with immunosuppressive properties. Rapamycin inhibits the mammalian target of rapamycin (mTOR) by blocking the mTOR complex 1 (mTORC1). mTOR is an atypical serine/threonine protein kinase, which controls cell growth,
Publikováno v:
Audiologyneuro-otology. 20(6)
Metformin is a commonly used antidiabetic drug. It has been shown that this drug activates the AMP-activated protein kinase, which inhibits downstream the mammalian target of rapamycin. In addition, several studies indicate that metformin reduces int
Autor:
Vesna Radojevic, Michael Sung, Eric Wei, Cristian Setz, Yves Brand, Katharina Leitmeyer, Andrea Glutz, Daniel Bodmer
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108146 (2014)
PLoS ONE
PLoS ONE
Hair cells and spiral ganglion neurons of the mammalian auditory system do not regenerate, and their loss leads to irreversible hearing loss. Aminoglycosides induce auditory hair cell death in vitro, and evidence suggests that phosphatidylinositol-3-