Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrea Gessner"'
Publikováno v:
Journal of Biomedical Materials Research Part A. :97-106
Pegylated polystyrene particles (PS-PEG) were prepared as a model system for artificial cells, by modification of carboxyl polystyrene particles (PS-COOH) with homo- and hetero-bifunctional polyethylene glycols (PEG, MW 1500, 3400, and 5000) containi
Publikováno v:
Journal of Controlled Release. 96:425-435
Sleeping sickness is a widely distributed disease in great parts of Africa. It is caused by Trypanosoma brucei gambiense and rhodiense, transmitted by the Tse-Tse fly. After a hemolymphatic stage, the parasites enter the central nervous system where
Publikováno v:
Journal of Biomedical Materials Research Part A. :319-326
The surface characteristics of intravenously administered particulate drug carriers decisively influence the protein adsorption that is regarded as a key factor for the in vivo fate of the carriers. Latex nanoparticles were synthesized to study the i
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 54:165-170
Plasma protein adsorption is regarded as a key factor for the in vivo organ distribution of intravenously administered colloidal drug carriers, and strongly depends on their surface characteristics, e.g. surface hydrophobicity or charge. A range of p
Publikováno v:
International Journal of Pharmaceutics. 214:87-91
The in vivo organ distribution of particulate drug carriers is decisively influenced by the interaction with plasma proteins after i.v. administration. Serum protein adsorption on lipid drug conjugate nanoparticles, a new carrier system for i.v. appl
Publikováno v:
Electrophoresis. 21:2438-2442
Two-dimensional electrophoresis (2-DE) was previously established for analysis of plasma protein adsorption patterns on particulate carriers for intravenous drug targeting. This study addresses a possible effect of polymeric particles on protein sepa
Publikováno v:
Journal of drug targeting. 10(5)
The objective of the present study was to incorporate the hydrophilic drug diminazenediaceturate at a high loading into lipid nanoparticles by creating nanoparticles from lipid-drug conjugates (LDC). IR and DSC data showed that the antitrypanosomal d