Systemic Treatment of Fabry Disease Using a Novel AAV9 Vector Expressing α-Galactosidase A

Autor: Maria Grazia Biferi, Mathilde Cohen-Tannoudji, Andrea García-Silva, Olga Souto-Rodríguez, Irene Viéitez-González, Beatriz San-Millán-Tejado, Andrea Fernández-Carrera, Tania Pérez-Márquez, Susana Teijeira-Bautista, Soraya Barrera, Vanesa Domínguez, Thibaut Marais, África González-Fernández, Martine Barkats, Saida Ortolano

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 1-17 (2021)

Fabry disease is a rare X-linked disorder affecting α-galactosidase A, a rate-limiting enzyme in lysosomal catabolism of glycosphingolipids. Current treatments present important limitations, such as low half-life and limited distribution, which gene

Externí odkaz: https://doaj.org/article/b2d13278a02c48deb45d598f9f6bd188

Neuropharmacological effects of the ethanolic extract of Sida acuta

Autor: Dora Benjumea, Fernando Alzate, Julieta Vásquez, José Angel Fontenla, Andrea García-Silva, Isabel Gómez-Betancur

Publikováno v: Revista Brasileira de Farmacognosia, Vol 26, Iss 2, Pp 209-215
Revista Brasileira de Farmacognosia v.26 n.2 2016
Revista Brasileira de Farmacognosia
Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
Revista Brasileira de Farmacognosia, Volume: 26, Issue: 2, Pages: 209-215, Published: APR 2016
Revista Brasileira de Farmacognosia, Vol 26, Iss 2, Pp 209-215 (2016)

Sida acuta Burm. f., Malvaceae, is regarded as astringent, tonic and useful in treating urinary diseases and blood disorders, bile, liver and as treatment for nervous diseases. Different methods were developed: sodium pentobarbital-induced sleeping t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f768df84c428615fb9ae67bf81f9bb
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2016000200209&lng=en&tlng=en