Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andrea García-Llorca"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
It has been known for some time that Carbonic Anhydrase (CA, EC 4.2.1.1) plays a complex role in vascular function, and in the regulation of vascular tone. Clinically employed CA inhibitors (CAIs) are used primarily to lower intraocular pressure in g
Externí odkaz:
https://doaj.org/article/f0a8cfbc6373412898fcb7a33fffb4de
Publikováno v:
Microorganisms, Vol 11, Iss 2, p 447 (2023)
The metabolic syndrome (MetS) is a complex disease of metabolic abnormalities, including obesity, insulin resistance, hypertension and dyslipidaemia, and it is associated with an increased risk of cardiovascular disease (CVD). Diabetic retinopathy (D
Externí odkaz:
https://doaj.org/article/ea172705df664afb86bf26ce497bbf91
Publikováno v:
Current Eye Research. 47:1615-1621
In this study, we investigated the vasodilation properties on pre-contracted retinal arteries of a restricted series of carbonic anhydrase inhibitors (CAIs) of the sulfonamide type with enhanced lipophilicity, to assess if it affects the potency of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7a93134af49570695e60caf9a163f1
https://doi.org/10.1080/02713683.2022.2126861
https://doi.org/10.1080/02713683.2022.2126861
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c24645f1970c20575df3dd574ab4d568
https://doi.org/10.3791/64964
https://doi.org/10.3791/64964
Autor:
Thor Eysteinsson, Andrea García‐Llorca
Publikováno v:
Acta Ophthalmologica. 100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d20fa0ff5a429a1fff10235d0fff22cd
https://doi.org/10.1111/j.1755-3768.2022.0644
https://doi.org/10.1111/j.1755-3768.2022.0644
Autor:
Thor Eysteinsson, Andrea García-Llorca, Arnar Oessur Hardarson, Daniela Vullo, Fabrizio Carta, Claudiu T. Supuran
Publikováno v:
International Journal of Molecular Sciences. 24:8140
It has been demonstrated previously that a variety of carbonic anhydrase inhibitors (CAIs) can induce vasodilation in pre-contracted retinal arteriolar segments although with different efficacy and potency. Since the CAIs tested so far are able to pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f2c481f4cdf94169e752aac81b3bd1a
https://doi.org/10.3390/ijms24098140
https://doi.org/10.3390/ijms24098140
Publikováno v:
Acta ophthalmologica. 100(8)
Mice carrying pathogenic variants in the microphthalmia transcription factor (Mitf) gene show structural and functional changes in the retina and retinal pigment epithelium. The purpose of this study was to assess the vascular changes in Mitf mice ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f8f9efcafc3a8ffb9a49beb861880f
https://pubmed.ncbi.nlm.nih.gov/35348289
https://pubmed.ncbi.nlm.nih.gov/35348289
Publikováno v:
Microorganisms. 11:447
The metabolic syndrome (MetS) is a complex disease of metabolic abnormalities, including obesity, insulin resistance, hypertension and dyslipidaemia, and it is associated with an increased risk of cardiovascular disease (CVD). Diabetic retinopathy (D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8084965e3b68de2355a3e63a9e449be5
https://doi.org/10.3390/microorganisms11020447
https://doi.org/10.3390/microorganisms11020447
Autor:
Margret H. Ogmundsdottir, Andrea García-Llorca, Snaefridur Gudmundsdottir Aspelund, Thor Eysteinsson, Eiríkur Steingrímsson
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Publisher's version (útgefin grein).
Mutations in the microphthalmia-associated transcription factor (Mitf) gene can cause retinal pigment epithelium (RPE) and retinal dysfunction and degeneration. We examined retinal and RPE structure and func
Mutations in the microphthalmia-associated transcription factor (Mitf) gene can cause retinal pigment epithelium (RPE) and retinal dysfunction and degeneration. We examined retinal and RPE structure and func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33336d6171822506fc754a0f9a687c6
http://link.springer.com/article/10.1038/s41598-019-51819-0
http://link.springer.com/article/10.1038/s41598-019-51819-0
Autor:
Andrea García Llorca, Eiríkur Steingrímsson, Margret H. Ogmundsdottir, Thor Eysteinsson, Franck Gesbert, Alba Sabaté, Lionel Larue
Publikováno v:
Acta Ophthalmologica. 97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebf9c96d1077ae88722b24ffc1f9003e
https://doi.org/10.1111/j.1755-3768.2019.5361
https://doi.org/10.1111/j.1755-3768.2019.5361