Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrea G. Brear"'
Autor:
Astrid Cornils, Ashish K Maurya, Lauren Tereshko, Julie Kennedy, Andrea G Brear, Veena Prahlad, Oliver E Blacque, Piali Sengupta
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006325 (2016)
The majority of cilia are formed and maintained by the highly conserved process of intraflagellar transport (IFT). Mutations in IFT genes lead to ciliary structural defects and systemic disorders termed ciliopathies. Here we show that the severely tr
Externí odkaz:
https://doaj.org/article/18b604c98b644cd79c5154c08b24574c
Autor:
Julie Kennedy, Oliver E. Blacque, Stefanie Kuhns, Andrea G. Brear, Piali Sengupta, Gavin J. McManus, Nils J. Lambacher, Anna Kazatskaya
Publikováno v:
Genetics. 207:1423-1440
Kazatskaya et al. uncover a role for the atypical MAP kinase MAPK15 in regulating primary cilium structure and morphology in both C. elegans and human.. Motile and immotile (or primary) cilia are microtubule-based structures that mediate multiple cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::586c1c6006f7bde14c0bb589f8deccf5
https://doi.org/10.1534/genetics.117.300383
https://doi.org/10.1534/genetics.117.300383
Autor:
Anna, Kazatskaya, Stefanie, Kuhns, Nils J, Lambacher, Julie E, Kennedy, Andrea G, Brear, Gavin J, McManus, Piali, Sengupta, Oliver E, Blacque
Publikováno v:
Genetics. 207(4)
Motile and immotile (or primary) cilia are microtubule-based structures that mediate multiple cellular functions, including the transduction of environmental cues, developmental signaling, cellular motility, and modulation of fluid flow. Although the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2553896e64f42fefd10da6f6a1d4164
https://pubmed.ncbi.nlm.nih.gov/29021280
https://pubmed.ncbi.nlm.nih.gov/29021280
Autor:
Andrea G. Brear, Julie Kennedy, Lauren Tereshko, Astrid Cornils, Ashish K. Maurya, Piali Sengupta, Veena Prahlad, Oliver E. Blacque
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006325 (2016)
The majority of cilia are formed and maintained by the highly conserved process of intraflagellar transport (IFT). Mutations in IFT genes lead to ciliary structural defects and systemic disorders termed ciliopathies. Here we show that the severely tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7972d97e27f0994d5f9df41c174f33b0
http://europepmc.org/articles/PMC5131903?pdf=render
http://europepmc.org/articles/PMC5131903?pdf=render
Autor:
Said Movahedi Naini, Maria H.J. van Osch, Sander van den Heuvel, Jagesh V. Shah, Geert J. P. L. Kops, Dirk M. Hentschel, Monique van der Voet, John R. Yates, Michael S. Manak, Ian McLeod, Andrea G. Brear
Publikováno v:
Journal of Cell Science. 123:1623-1633
Error-free chromosome segregation depends on timely activation of the multi-subunit E3 ubiquitin ligase APC/C. Activation of the APC/C initiates chromosome segregation and mitotic exit by targeting critical cell-cycle regulators for destruction. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ef2381a7c829c7ee0bf2aef85193b8
https://doi.org/10.1242/jcs.061549
https://doi.org/10.1242/jcs.061549
Publikováno v:
Genetics. 197(2)
The localization of signaling molecules such as G protein-coupled receptors (GPCRs) to primary cilia is essential for correct signal transduction. Detailed studies over the past decade have begun to elucidate the diverse sequences and trafficking mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1cf146dcfb1bf26f6d9e0d664d9f589
https://pubmed.ncbi.nlm.nih.gov/24646679
https://pubmed.ncbi.nlm.nih.gov/24646679
Publikováno v:
Journal of cell science. 126(Pt 19)
Summary Primary cilia are ubiquitous sensory organelles that concentrate transmembrane signaling proteins essential for sensing environmental cues. Mislocalization of crucial ciliary signaling proteins, such as the tetrameric cyclic nucleotide-gated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c2ee5f474721fed90924e362b1281d
https://pubmed.ncbi.nlm.nih.gov/23886944
https://pubmed.ncbi.nlm.nih.gov/23886944