Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrea G. Brear"'
Autor:
Astrid Cornils, Ashish K Maurya, Lauren Tereshko, Julie Kennedy, Andrea G Brear, Veena Prahlad, Oliver E Blacque, Piali Sengupta
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006325 (2016)
The majority of cilia are formed and maintained by the highly conserved process of intraflagellar transport (IFT). Mutations in IFT genes lead to ciliary structural defects and systemic disorders termed ciliopathies. Here we show that the severely tr
Externí odkaz:
https://doaj.org/article/18b604c98b644cd79c5154c08b24574c
Autor:
Julie Kennedy, Oliver E. Blacque, Stefanie Kuhns, Andrea G. Brear, Piali Sengupta, Gavin J. McManus, Nils J. Lambacher, Anna Kazatskaya
Publikováno v:
Genetics. 207:1423-1440
Kazatskaya et al. uncover a role for the atypical MAP kinase MAPK15 in regulating primary cilium structure and morphology in both C. elegans and human.. Motile and immotile (or primary) cilia are microtubule-based structures that mediate multiple cel
Autor:
Anna, Kazatskaya, Stefanie, Kuhns, Nils J, Lambacher, Julie E, Kennedy, Andrea G, Brear, Gavin J, McManus, Piali, Sengupta, Oliver E, Blacque
Publikováno v:
Genetics. 207(4)
Motile and immotile (or primary) cilia are microtubule-based structures that mediate multiple cellular functions, including the transduction of environmental cues, developmental signaling, cellular motility, and modulation of fluid flow. Although the
Autor:
Andrea G. Brear, Julie Kennedy, Lauren Tereshko, Astrid Cornils, Ashish K. Maurya, Piali Sengupta, Veena Prahlad, Oliver E. Blacque
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006325 (2016)
The majority of cilia are formed and maintained by the highly conserved process of intraflagellar transport (IFT). Mutations in IFT genes lead to ciliary structural defects and systemic disorders termed ciliopathies. Here we show that the severely tr
Autor:
Said Movahedi Naini, Maria H.J. van Osch, Sander van den Heuvel, Jagesh V. Shah, Geert J. P. L. Kops, Dirk M. Hentschel, Monique van der Voet, John R. Yates, Michael S. Manak, Ian McLeod, Andrea G. Brear
Publikováno v:
Journal of Cell Science. 123:1623-1633
Error-free chromosome segregation depends on timely activation of the multi-subunit E3 ubiquitin ligase APC/C. Activation of the APC/C initiates chromosome segregation and mitotic exit by targeting critical cell-cycle regulators for destruction. The
Publikováno v:
Genetics. 197(2)
The localization of signaling molecules such as G protein-coupled receptors (GPCRs) to primary cilia is essential for correct signal transduction. Detailed studies over the past decade have begun to elucidate the diverse sequences and trafficking mec
Publikováno v:
Journal of cell science. 126(Pt 19)
Summary Primary cilia are ubiquitous sensory organelles that concentrate transmembrane signaling proteins essential for sensing environmental cues. Mislocalization of crucial ciliary signaling proteins, such as the tetrameric cyclic nucleotide-gated
Autor:
Cornils, Astrid1, Maurya, Ashish K.1, Tereshko, Lauren1, Kennedy, Julie2, Brear, Andrea G.1, Prahlad, Veena3, Blacque, Oliver E.2, Sengupta, Piali1 sengupta@brandeis.edu
Publikováno v:
PLoS Genetics. 12/1/2016, Vol. 12 Issue 12, p1-24. 24p.
Publikováno v:
Journal of Cell Science; Oct2013, Vol. 126 Issue 19, p4381-4395, 15p