Crystallization of a human galectin-3 variant with two ordered segments in the shortened N-terminal tail

Autor: Andrea Flores-Ibarra, Sabine Vértesy, Francisco J. Medrano, Hans-Joachim Gabius, Antonio Romero

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

Abstract Among members of the family of adhesion/growth-regulatory galectins, galectin-3 (Gal-3) bears a unique modular architecture. A N-terminal tail (NT) consisting of the N-terminal segment (NTS) and nine collagen-like repeats is linked to the ca

Externí odkaz: https://doaj.org/article/2c7acd4b69ae4cc98caad13f41be21b1

Novel Devices for Transporting Protein Crystals to the Synchrotron Facilities and Thermal Protection of Protein Crystals

Autor: Andrea Flores-Ibarra, Camila Campos-Escamilla, Yasel Guerra, Enrique Rudiño-Piñera, Nicola Demitri, Maurizio Polentarutti, Mayra Cuéllar-Cruz, Abel Moreno

Publikováno v: Crystals, Vol 8, Iss 9, p 340 (2018)

In this article, we use novel and non-conventional devices, based on polyolefins that help to increase the thermal protection of protein crystals in their crystallization conditions for crystallographic applications. The present contribution deals wi

Externí odkaz: https://doaj.org/article/17d63482e1a743c2a6f64459345e3568

Galectin-related protein: An integral member of the network of chicken galectins 1. From strong sequence conservation of the gene confined to vertebrates to biochemical characteristics of the chicken protein and its crystal structure

Autor: Jürgen Kopitz, Sabine Vértesy, Herbert Kaltner, Joachim C. Manning, Nailya Khasbiullina, Nicolai V. Bovin, Malwina Michalak, Antonio A. Romero, Gabriel García Caballero, Federico M. Ruiz, Hans-Joachim Gabius, Andrea Flores-Ibarra, Sabine André

Publikováno v: Biochimica et Biophysica Acta. General Subjects

Background Endogenous lectins are multifunctional effectors in cell physiology. Adding the sixth member of the galectin family in chicken, a model organism for systematic profiling of these adhesion/growth-regulatory proteins, is a step toward compre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e971fb3b5834467fd4ace702d0d33b1
https://doi.org/10.1016/j.bbagen.2016.06.001

Crystallization of a human galectin-3 variant with two ordered segments in the shortened N-terminal tail

Autor: Hans-Joachim Gabius, Francisco J. Medrano, Antonio A. Romero, Sabine Vértesy, Andrea Flores-Ibarra

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports
'Scientific Reports ', vol: 8, pages: 9835-1-9835-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

11 p.-8 fig.
Among members of the family of adhesion/growth-regulatory galectins, galectin-3 (Gal-3) bears a unique modular architecture. A N-terminal tail (NT) consisting of the N-terminal segment (NTS) and nine collagen-like repeatsis linked t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7bf9df499c05a89d81bc436e97d4435
http://hdl.handle.net/10261/167433

Preliminary X-ray crystallographic analysis of an engineered variant of human chimera-type galectin-3 with a shortened N-terminal domain

Autor: Hans-Joachim Gabius, Federico M. Ruiz, Antonio A. Romero, Sabine André, Sabine Vértesy, Andrea Flores-Ibarra

How lectins translate sugar-encoded information into cellular effects not only depends on glycan recognition. Other domains of the protein can contribute to the functional profile of a lectin. Human galectin-3 (Gal-3), an adhesion/growth-regulatory g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6f4b0251d313767b88d50811d6a234
https://europepmc.org/articles/PMC4321473/