Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andrea F. Moura"'
Autor:
MAURICIO M. VICTOR, JORGE M. DAVID, MARIA C.K. SAKUKUMA, LETÍCIA V. COSTA-LOTUFO, ANDREA F. MOURA, ANA J. ARAÚJO
Publikováno v:
Anais da Academia Brasileira de Ciências, Iss 0 (2017)
ABSTRACT Natural steroids and triterpenes such as b-sitosterol, stigmasterol, lupeol, ursolic and betulinic acids were transformed into its hexanoic and oleic esters, to evaluate the influence of chemical modification towards the cytotoxic activities
Externí odkaz:
https://doaj.org/article/b870eed8be064d6faa62ad026b49e805
Autor:
Szilárd Molnár, Aline Bernardes, Wesley F. Vaz, Allen G. Oliver, Pál Perjési, Caridad Noda-Perez, Andrea F. Moura, Jean M. F. Custodio
Publikováno v:
New Journal of Chemistry. 45:15267-15279
Apoptosis is a defense mechanism against pre-cancerous and infected cells. Although the applicability of β-ionone against diverse cancer cell lines has been exhaustively investigated, the apoptotic activity of terpenoid-like chalcones, as well as th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7940a811f8a2d88a95c8233cae055402
https://doi.org/10.1039/d1nj02086b
https://doi.org/10.1039/d1nj02086b
Autor:
Maria Gabriela Araújo Mendes, Ana Jérsia Araújo, José Delano Barreto Marinho Filho, Ayslan Batista Barros, Durcilene Alves da Silva, Alyne Rodrigues de Araújo, Stéphanie Aguiar de Negreiros Matos Silva, Tatiane Caroline Daboit, Andrea F. Moura, Jessica Maria Teles Souza
Publikováno v:
Phytochemistry Letters. 39:173-181
Plant extracts and components are commonly used in popular medicine to relieve the symptoms of several diseases. They can also be used scientifically for drug testing due to their wide biological potential, acting as antibacterial, antifungal, and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::891dda8e9d6e7a9e8b5fb319113cf07a
https://doi.org/10.1016/j.phytol.2020.08.010
https://doi.org/10.1016/j.phytol.2020.08.010
Autor:
Taynara Simão Matos, Nilberto R.F. Nascimento, Talles Luann Abrantes Ferreira, Manoel Odorico de Moraes, Matheus Carlos Matos da Silva, Norberto K.V. Monteiro, Otília Deusdênia L. Pessoa, Andrea F. Moura, Alison da Silva Batista, Fábio do Nascimento Ávila, Lidivânia Silva Freitas Mesquita
Publikováno v:
Planta Medica. 87:124-135
Two new diterpenoid derivatives 7α,12β,17-triacetoxy-6β,19-dihydroxy-13β,16-spirocicloabiet-8-ene-11,14-dione (1) and 6β-acetoxy-3β,7α,12α-trihydroxy-13β,16-spirocicloabiet-8-ene-11,14-dione (2) along with 11 (3–13) miscellaneous compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cfe32f5cfa568f78035bb500b3a8d1
https://doi.org/10.1055/a-1209-3252
https://doi.org/10.1055/a-1209-3252
Autor:
Andrea F. Moura, Felipe T. Martins, Manoel Odorico de Moraes, Aline Bernardes, Cameron Capeletti da Silva, Caridad N. Perez, Mirian R. C. de Castro, Raquel Ferreira Naves
Publikováno v:
Arabian Journal of Chemistry, Vol 13, Iss 1, Pp 1345-1354 (2020)
We here report the synthesis of novel chalcone-sulfonamide compounds based on the hybridization at 2′ position and nitro substitution at the side chalcone phenyl ring followed by tandem cyclization into quinolinone derivatives and then a further al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d6ff84b74fb0d7e4334377df781da1
http://www.sciencedirect.com/science/article/pii/S1878535217302137
http://www.sciencedirect.com/science/article/pii/S1878535217302137
Autor:
Andrea F. Moura, Jean M. F. Custodio, Manoel Odorico de Moraes, Caridad N. Perez, Hamilton B. Napolitano
Publikováno v:
New Journal of Chemistry. 44:3294-3309
Science is constantly looking for new strategies to combat tumor progression and improve patient care due to increasing cancer incidence and high mortality. Although many chalcone analogues have been synthesized and studied because of their activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eb6ccad3e367cdb79ab446ffee29c4e
https://doi.org/10.1039/c9nj05612b
https://doi.org/10.1039/c9nj05612b
Autor:
Manoel Odorico de Moraes, Laszlo Prokai, Jean M. F. Custodio, Hamilton B. Napolitano, Pál Perjési, Caridad N. Perez, Andrea F. Moura, Giulio D. C. d’Oliveira
Publikováno v:
Medicinal Chemistry Research. 28:1448-1460
Non-enzyme catalyzed nucleophilic addition of reduced glutathione (GSH) onto two open-chain sulfonamide chalcones and two quinolinone-chalcone hybrids were studied to investigate the relationship between tumor cell cytotoxic activities and GSH-reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::699f53cca9adf9194543fa50c0a30ff2
https://doi.org/10.1007/s00044-019-02384-8
https://doi.org/10.1007/s00044-019-02384-8
Autor:
Caridad N. Perez, Hamilton B. Napolitano, Aline Bernardes, Mirian R. C. de Castro, Jean M. F. Custodio, Wesley F. Vaz, Felipe T. Martins, Raquel Ferreira Naves, Manoel Odorico de Moraes, Cameron Capeletti da Silva, Andrea F. Moura
Publikováno v:
Journal of Molecular Structure. 1175:389-397
Investigation of multiple crystal forms of a substance and how these forms influence their properties are of great importance to the medicinal chemistry field, impacting strongly on the discovery of new drugs such as anticancer agents. Specifically,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d49a3254b87b6ee6aa57f05030631b0
https://doi.org/10.1016/j.molstruc.2018.07.059
https://doi.org/10.1016/j.molstruc.2018.07.059
Autor:
Alessandra C. Pinheiro, Francisco Washington Araújo Barros-Nepomuceno, Carlos Roberto Koscky Paier, Claudia Pessoa, Marcus V. N. de Souza, Sarah Sant’Anna Maranhão, Augusto César Aragão Oliveira, Thais Cristina Mendonça Nogueira, Daisy Jereissati Barbosa Lima, Andrea F. Moura
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:126851
Quinoxaline derivatives are reported as antineoplastic agents against a variety of human cancer cell lines, with some compounds being submitted to clinical trials. In this work, we report the synthesis, characterization and cytotoxicity potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f0cd6fbed33fd539284392dcb63dd7
https://doi.org/10.1016/j.bmcl.2019.126851
https://doi.org/10.1016/j.bmcl.2019.126851
Autor:
Manoel Odorico de Moraes, Giulio D. C. D’Oliveira, Caridad N. Perez, Luciano M. Lião, Andrea F. Moura
Publikováno v:
Journal of the Brazilian Chemical Society, Volume: 29, Issue: 11, Pages: 2308-2325, Published: NOV 2018
Journal of the Brazilian Chemical Society v.29 n.11 2018
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society v.29 n.11 2018
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Chalcone-quinolinone hybrid compounds, as well as the synthesis of such compounds, have few reports in the literature. Such compounds may be quite useful in therapeutics, since various biological activities are reported for both chalcones and quinoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e99ec219102bf803f5dcf355db0f0d
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532018001102308&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532018001102308&lng=en&tlng=en
