Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andrea E. Sperry"'
Autor:
Anjul Khadria, Chad D. Paavola, Konstantin Maslov, Francisco A. Valenzuela, Andrea E. Sperry, Amy L. Cox, Rui Cao, Junhui Shi, Patricia L. Brown-Augsburger, Emmanuel Lozano, Ross L. Blankenship, Ranajoy Majumdar, Scott A. Bradley, John M. Beals, Sunday S. Oladipupo, Lihong V. Wang
Publikováno v:
Molecular Metabolism, Vol 62, Iss , Pp 101522- (2022)
Objective: Ultra-rapid insulin formulations control postprandial hyperglycemia; however, inadequate understanding of injection site absorption mechanisms is limiting further advancement. We used photoacoustic imaging to investigate the injection site
Externí odkaz:
https://doaj.org/article/4e686fb7d1214da195f3ad2aa1b7871d
Autor:
Michael J. Berna, Patrick I. Eacho, Ryan John Hansen, Thomas P. Beyer, Andrea E Sperry, Victor J. Wroblewski, Krista Schroeder
Publikováno v:
mAbs
A recent report described a novel mechanism of action for an anti-proprotein convertase subtilisin-kexin type 9 (PCSK9) monoclonal antibody (LY3015014, or LY), wherein the antibody has improved potency and duration of action due to the PCSK9 epitope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f329fd3fa05d9bccc02e341e2f483242
https://doi.org/10.1080/19420862.2016.1270490
https://doi.org/10.1080/19420862.2016.1270490
Autor:
Andrew Ihor Korytko, J. Jacobs, Andrea E Sperry, John Michael Beals, Jessica L. Friedrich, Amy L. Cox, Steven D. Kahl, Eric D. Hawkins, Julie S. Moyers, Hana E. Baker, Ryan John Hansen, Volker Schellenberger, Chen Zhang, Michael E. Christe, M. Dodson Michael, Debra L. Konkol, D. Bruce Baldwin
Publikováno v:
Diabetes. 67
To optimize the action of exogenously administered insulin, we employed XTEN® technology to create insulins with variably sized XTEN amino acid polymers. Recombinant fusions of XTEN polymers linked to insulin lispro with an A21G mutation were prepar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e51120da1ca78912cf5dabd1af626da
https://doi.org/10.2337/db18-90-lb
https://doi.org/10.2337/db18-90-lb
Publikováno v:
Biochemistry. 43:8483-8493
The effect of 26 different membrane-perturbing agents on the activity and phase distribution of inositol phosphorylceramide synthase (IPC synthase) activity in crude Candida albicans membranes was investigated. The nonionic detergents Triton X-100, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1200ea742bb222fb3b1542c4f3461f1f
https://doi.org/10.1021/bi049141u
https://doi.org/10.1021/bi049141u
Autor:
Stephanie E. Sen, Andrea E Sperry
Publikováno v:
Insect Biochemistry and Molecular Biology. 32:889-899
Farnesyl diphosphate synthase (FPP synthase) is a ubiquitous enzyme that is required for the biosynthesis of sesquiterpenes, dolichols ubiquinones, and prenylated proteins in insects. We report on the partial purification and characterization of an F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adfb17a87ea87679ec2e5eaf26389e5
https://doi.org/10.1016/s0965-1748(01)00178-3
https://doi.org/10.1016/s0965-1748(01)00178-3
Publikováno v:
Insect biochemistry and molecular biology. 37(1)
Prenyltransferase activity derived from the corpora allata (CA) of the lepidopteran insect, Manduca sexta , has been characterized. The coupling of allylic substrates DMAPP and GPP with the non-allylic substrate IPP was evaluated using CA homogenates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed1a992e9abbcf5b996f33f90d9b4ab
https://pubmed.ncbi.nlm.nih.gov/17175444
https://pubmed.ncbi.nlm.nih.gov/17175444
Publikováno v:
Insect biochemistry and molecular biology. 33(6)
The oxidation of farnesol to farnesal is an important step in insect juvenile hormone (JH) biosynthesis and is mediated by one or more alcohol oxidases located within the minute endocrine gland, the corpus allatum. Because lepidopteran insects have t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1336e41ca032b3f59a5e6decf5f2f29e
https://pubmed.ncbi.nlm.nih.gov/12770578
https://pubmed.ncbi.nlm.nih.gov/12770578
Autor:
Andrea E Sperry, Stephanie E. Sen
Publikováno v:
Insect biochemistry and molecular biology. 31(2)
The oxidation of farnesol to farnesoic acid is a key step in insect juvenile hormone biosynthesis. We herein present preliminary characterization of the enzyme-catalyzed oxidation of farnesol to farnesal in larval corpora allata homogenates of the to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26337303f7ce7ba2cfffbed88c80e884
https://pubmed.ncbi.nlm.nih.gov/11164339
https://pubmed.ncbi.nlm.nih.gov/11164339