Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andrea E. Münsterberg"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Hepatocellular carcinoma (HCC) is the most common type of liver cancer, which is among the most lethal tumours. Combination therapy exploits multiple drugs to target key pathways synergistically to reduce tumour growth. Isothiocyanates
Externí odkaz:
https://doaj.org/article/dfa5eb5f3c714207ae3077b320a48496
Autor:
Gabriele Strusi, Caterina M. Suelzu, Shannon Weldon, Jennifer Giffin, Andrea E. Münsterberg, Yongping Bao
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2390 (2023)
Cancerous cells are characterised by their ability to invade, metastasise, and induce angiogenesis. Tumour cells use various molecules that can be targeted to reverse these processes. Dasatinib, a potent Src inhibitor, has shown promising results in
Externí odkaz:
https://doaj.org/article/65fd31645ae047ff8c782e8b8d32ffdc
Autor:
Gi Fay Mok, Leighton Folkes, Shannon A. Weldon, Eirini Maniou, Victor Martinez-Heredia, Alice M. Godden, Ruth M. Williams, Tatjana Sauka-Spengler, Grant N. Wheeler, Simon Moxon, Andrea E. Münsterberg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
How paraxial mesoderm formation and differentiation is regulated is unclear. Here, the authors identify accessible chromatin and gene expression signatures that define different stages of paraxial mesoderm development in the chick and identify CREs i
Externí odkaz:
https://doaj.org/article/83e65e791fea4260aa9246e9733957f6
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 5 (2017)
Externí odkaz:
https://doaj.org/article/279563c8efd9428eba921ad4a831f30d
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0219721 (2020)
Wnt/FZD signalling activity is required for spinal cord development, including the dorsal-ventral patterning of the neural tube, where it affects proliferation and specification of neurons. Wnt ligands initiate canonical, β -catenin-dependent, signa
Externí odkaz:
https://doaj.org/article/305c9f777b654b6cac6ee97d14cdbc43
Autor:
Ayisha Ahmed, Nicole J Ward, Simon Moxon, Sara Lopez-Gomollon, Camille Viaut, Matthew L Tomlinson, Ilya Patrushev, Michael J Gilchrist, Tamas Dalmay, Dario Dotlic, Andrea E Münsterberg, Grant N Wheeler
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0138313 (2015)
MicroRNAs (miRNAs) are short, non-coding RNAs around 22 nucleotides long. They inhibit gene expression either by translational repression or by causing the degradation of the mRNAs they bind to. Many are highly conserved amongst diverse organisms and
Externí odkaz:
https://doaj.org/article/67df66c51d424b86bd3898198bbd5a00