Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrea E. Calvert"'
Autor:
Yinu Wang, Andrea E. Calvert, Horacio Cardenas, Jonathon S. Rink, Dominik Nahotko, Wenan Qiang, C. Estelle Ndukwe, Fukai Chen, Russell Keathley, Yaqi Zhang, Ji‐Xin Cheng, C. Shad Thaxton, Daniela Matei
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Platinum (Pt)‐based chemotherapy is the main treatment for ovarian cancer (OC); however, most patients develop Pt resistance (Pt‐R). This work shows that Pt‐R OC cells increase intracellular cholesterol through uptake via the HDL recep
Externí odkaz:
https://doaj.org/article/c74208f5f91d408dacb341f964db8aef
Autor:
Andrea E. Calvert, Alexandra Chalastanis, Yongfei Wu, Lisa A. Hurley, Fotini M. Kouri, Yingtao Bi, Maureen Kachman, Jasmine L. May, Elizabeth Bartom, Youjia Hua, Rama K. Mishra, Gary E. Schiltz, Oleksii Dubrovskyi, Andrew P. Mazar, Marcus E. Peter, Hongwu Zheng, C. David James, Charles F. Burant, Navdeep S. Chandel, Ramana V. Davuluri, Craig Horbinski, Alexander H. Stegh
Publikováno v:
Cell Reports, Vol 19, Iss 9, Pp 1858-1873 (2017)
Oncogenic mutations in two isocitrate dehydrogenase (IDH)-encoding genes (IDH1 and IDH2) have been identified in acute myelogenous leukemia, low-grade glioma, and secondary glioblastoma (GBM). Our in silico and wet-bench analyses indicate that non-mu
Externí odkaz:
https://doaj.org/article/f4d292ac8f8346f8ab26ed8e258f99d4
Autor:
Nihal Kaplan, Stephen E. Henrich, Andrea E. Calvert, Kaylin M. McMahon, Han Peng, Robert M. Lavker, Kurt Q. Lu, C. Shad Thaxton, U. Onay
Publikováno v:
Ocul Surf
Medicine has been a great beneficiary of the nanotechnology revolution. Nanotechnology involves the synthesis of functional materials with at least one size dimension between 1 and 100 nm. Advances in the field have enabled the synthesis of bio-nanop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192ff43e9de56496fd30889532fdbb73
https://doi.org/10.1016/j.jtos.2021.03.001
https://doi.org/10.1016/j.jtos.2021.03.001
Autor:
Saber M. Hussain, John T. Wilkins, Andrea E. Calvert, C. Shad Thaxton, Kaylin M. McMahon, Irina S. Dementieva
Publikováno v:
ACS Sens
High-density lipoproteins (HDL) are constitutionally dynamic nanoparticles that circulate in the blood. The biological functions of HDLs are impacted by interchangeable surface chemical components, like cholesterol and HDL-associated proteins. Curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8127f2ebd6dbc3d369c5c084a87a567
https://doi.org/10.1021/acssensors.0c01117
https://doi.org/10.1021/acssensors.0c01117
Autor:
Timothy Joel Feliciano, Stephen E. Henrich, Andrea E. Calvert, C. Shad Thaxton, Benedito A. Carneiro, Anthony Mega, Andre De Souza, Michael P. Plebanek, Samuel Parrish, Kaylin M. McMahon, Fabio Tavora
Publikováno v:
Journal of Extracellular Vesicles
Primary tumours can establish long‐range communication with distant organs to transform them into fertile soil for circulating tumour cells to implant and proliferate, a process called pre‐metastatic niche (PMN) formation. Tumour‐derived extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d761e18d983463d2ae5fc28005532f
http://europepmc.org/articles/PMC7775568
http://europepmc.org/articles/PMC7775568
Autor:
Kaylin M. McMahon, Adam Yuh Lin, Reem Karmali, Andrea E. Calvert, Shuo Yang, C. Shad Thaxton, Jonathan Moreira, Jonathan S. Rink, Amir Behdad, Tim Taxter, Amy Chadburn, Leo I. Gordon
Publikováno v:
The Journal of Biological Chemistry
Normal human cells can either synthesize cholesterol or take it up from lipoproteins to meet their metabolic requirements. In some malignant cells, de novo cholesterol synthesis genes are transcriptionally silent or mutated, meaning that cholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7cb836b9ce6f454dd5dbd3c4704784a
http://europepmc.org/articles/PMC7949030
http://europepmc.org/articles/PMC7949030
Autor:
Colby Shad Thaxton, Timothy Taxter, Amy Lin, Shuo Yang, Amir Behdad, Reem Karmali, Leo I. Gordon, Amy Chadburn, Andrea E. Calvert, Kaylin M. McMahon, Jonathan Moreira, Jonathan S. Rink
Normal human cells can either synthesize or uptake cholesterol from lipoproteins to meet their metabolic requirements. Some malignant cells absolutely require cholesterol uptake from lipoproteins for survival because de novo cholesterol synthesis gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f7bf2c1371258efe29864892dcd91b1
https://doi.org/10.1101/2020.06.16.155242
https://doi.org/10.1101/2020.06.16.155242
Autor:
Jasmine L. May, Serena Tommasini-Ghelfi, Alexander H. Stegh, Peng Gao, Foteini Kouri, Andrew Lee, Andrea E. Calvert, Navdeep S. Chandel, Yanrong Ji, Craig Horbinski, Juan Liu, Jason W. Locasale, Lisa A. Hurley, Ramana V. Davuluri
Publikováno v:
Science Advances
IDH3α promotes glioblastoma progression and links mitochondrial metabolism to cSHMT-controlled one-carbon metabolism.
Mutation or transcriptional up-regulation of isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) promotes cancer progression thr
Mutation or transcriptional up-regulation of isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) promotes cancer progression thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef98aa670ef786fc34c0778b2932599
https://doi.org/10.1126/sciadv.aat0456
https://doi.org/10.1126/sciadv.aat0456
Autor:
Leo I. Gordon, Shuo Yang, Jonathan S. Rink, Amir Behdad, Kaylin M. McMahon, Reem Karmali, Colby Shad Thaxton, Adam Yuh Lin, Andrea E. Calvert
Publikováno v:
Blood Cancer Discovery. 1:PO-11
Introduction: In B-cell lymphomas, disparate molecular aberrations often produce common onco-metabolic phenotypes, including a dependency upon cholesterol uptake from serum lipoproteins rather than de novo synthesis. Recent reports have linked cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb89afb0e1c45a769d6987ed51b36891
https://doi.org/10.1158/2643-3249.lymphoma20-po-11
https://doi.org/10.1158/2643-3249.lymphoma20-po-11
Autor:
Han Peng, Nihal Kaplan, Kurt Q. Lu, Colby Shad Thaxton, Kaylin M. McMahon, Wending Yang, Robert M. Lavker, Andrea E. Calvert, Junyi Wang
Publikováno v:
Adv Ther (Weinh)
microRNAs regulate numerous biological processes, making them potential therapeutic agents. Problems with delivery and stability of these molecules have limited their usefulness as treatments. We demonstrate that synthetic high-density lipoprotein na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c84dab78251cc3e0c8a95b3ed28781
https://doi.org/10.1002/adtp.202000138
https://doi.org/10.1002/adtp.202000138