Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Andrea E. Best"'
Autor:
Charles Locke, Peter W. Reeh, W. Rachel Duan, Ahmed A. Othman, Klaus Schaffler, Connie R. Faltynek, Wolfram Nothaft, Andrea E. Best
Publikováno v:
British Journal of Clinical Pharmacology. 75:404-414
Aims Laser (radiant-heat) evoked potentials (LEPs) from vertex-EEG peak-to-peak (PtP) amplitude were used to determine acute antinociceptive/antihyperalgesic efficacy of ABT-102, a novel TRPV1 antagonist efficacious in preclinical pain models, compar
Autor:
Michael C. Rowbotham, Y. Pritchett, Andrea E. Best, W. Rachel Duan, Armen Arslanian, Qian Zhou, Brett R. Stacey, Wolfram Nothaft
Publikováno v:
Pain. 153:862-868
Preclinical and clinical studies suggest that neuronal nicotinic receptor (NNR) agonists may be a novel and effective therapy for numerous painful conditions. Analgesic efficacy and safety of the highly selective α(4)β(2) NNR agonist ABT-894 was ev