Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Andrea Dlasková"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Previously, a number of ~ 1.4 of mitochondrial DNA (mtDNA) molecules in a single nucleoid was reported, which would reflect a minimum nucleoid division. We applied 3D-double-color direct stochastic optical reconstruction microscopy (dSTORM),
Externí odkaz:
https://doaj.org/article/11d4c7119b4b4b58a18f60cf7ee25933
Publikováno v:
Antioxidants & Redox Signaling.
Publikováno v:
Antioxidants & Redox Signaling.
Autor:
Petr Ježek, Blanka Holendová, Martin Jabůrek, Jan Tauber, Andrea Dlasková, Lydie Plecitá-Hlavatá
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 197 (2021)
Pancreatic β-cell insulin secretion, which responds to various secretagogues and hormonal regulations, is reviewed here, emphasizing the fundamental redox signaling by NADPH oxidase 4- (NOX4-) mediated H2O2 production for glucose-stimulated insulin
Externí odkaz:
https://doaj.org/article/a4811a875d4446ca9f8d9188dbc70cbf
Background Previously, ~ 1.4 of mitochondrial DNA (mtDNA) molecules in a single nucleoid was reported. Such a minimum number would reflect a minimum nucloid division. Results We applied 3D-double-color direct stochastic optical reconstruction microsc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cb13675a45e168541a0c6a0a4d8f38a
https://doi.org/10.21203/rs.3.rs-2063370/v1
https://doi.org/10.21203/rs.3.rs-2063370/v1
Autor:
Alberto Leguina-Ruzzi, Anežka Vodičková, Blanka Holendová, Vojtěch Pavluch, Jan Tauber, Hana Engstová, Andrea Dlasková, Petr Ježek
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 1026 (2020)
Transcript levels for selected ATP synthase membrane FO-subunits—including DAPIT—in INS-1E cells were found to be sensitive to lowering glucose down from 11 mM, in which these cells are routinely cultured. Depending on conditions, the diminished
Externí odkaz:
https://doaj.org/article/b2d0e5d6348141e39c34cc0b14a77832
Autor:
Jan Ježek, Blanka Holendová, Tomáš Špaček, Lydie Plecitá-Hlavatá, Jan Tauber, Klára Gotvaldová, Vladimír Křen, Lucie Petrásková, Hana Engstová, Andrea Dlasková, Petr Ježek, Katarína Smolková, Jitka Špačková
Publikováno v:
Antioxidants & Redox Signaling
Aims: Glucose-stimulated insulin secretion (GSIS) in pancreatic β cells was expected to enhance mitochondrial superoxide formation. Hence, we elucidated relevant redox equilibria. Results: Unexpectedly, INS-1E cells at transitions from 3 (11 mM; pan
Autor:
Jan Tauber, Petr Ježek, Martin Jabůrek, Blanka Holendová, Andrea Dlasková, Lydie Plecitá-Hlavatá
In this review, we place redox signaling in pancreatic β-cells to the context with signaling pathways leading to insulin secretion, acting for example upon the action of incretins (GLP-1, GIP) and the metabotropic receptor GPR40. Besides a brief des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f545b36194d8d6da16f774fc1a9dfd7
https://doi.org/10.5772/intechopen.94312
https://doi.org/10.5772/intechopen.94312
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1863:148795
Publikováno v:
Antioxidantsredox signaling. 36(13-15)
Significance: Mitochondria determine glucose-stimulated insulin secretion (GSIS) in pancreatic β-cells by elevating ATP synthesis. As the metabolic and redox hub, mitochondria provide numerous link...