Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Andrea D van Dam"'
1
Akademický článek
The GPR120 agonist TUG‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat
Autor: Maaike Schilperoort, Andrea D van Dam, Geerte Hoeke, Irina G Shabalina, Anthony Okolo, Aylin C Hanyaloglu, Lea H Dib, Isabel M Mol, Natarin Caengprasath, Yi‐Wah Chan, Sami Damak, Anne Reifel Miller, Tamer Coskun, Bharat Shimpukade, Trond Ulven, Sander Kooijman, Patrick CN Rensen, Mark Christian
Publikováno v: EMBO Molecular Medicine, Vol 10, Iss 3, Pp 1-18 (2018)
Abstract Brown adipose tissue (BAT) activation stimulates energy expenditure in human adults, which makes it an attractive target to combat obesity and related disorders. Recent studies demonstrated a role for G protein‐coupled receptor 120 (GPR120
Externí odkaz: https://doaj.org/article/435be6144c2f46c4be6f9f0833c44ebc
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2
Akademický článek
Higher Plasma Sclerostin and Lower Wnt Signaling Gene Expression in White Adipose Tissue of Prediabetic South Asian Men Compared with White Caucasian Men
Autor: Laura G.M. Janssen, Andrea D. van Dam, Mark J.W. Hanssen, Sander Kooijman, Kimberly J. Nahon, Hanneke Reinders, Ingrid M. Jazet, Wouter D. van Marken Lichtenbelt, Patrick C.N. Rensen, Natasha M. Appelman-Dijkstra, Mariëtte R. Boon
Publikováno v: Diabetes & Metabolism Journal, Vol 44, Iss 2, Pp 326-335 (2020)
BackgroundSouth Asians generally have an unfavourable metabolic phenotype compared with white Caucasians, including central obesity and insulin resistance. The Wnt protein family interacts with insulin signaling, and impaired Wnt signaling is associa
Externí odkaz: https://doaj.org/article/e185adc9d6304da6bc3ca6cd353befeb
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3
Higher Plasma Sclerostin and Lower Wnt Signaling Gene Expression in White Adipose Tissue of Prediabetic South Asian Men Compared with White Caucasian Men
Autor: Natasha M. Appelman-Dijkstra, Kimberly J. Nahon, Mark J. W. Hanssen, Mariëtte R. Boon, Ingrid M. Jazet, Laura G.M. Janssen, Patrick C.N. Rensen, Hanneke Reinders, Wouter D. van Marken Lichtenbelt, Sander Kooijman, Andrea D. van Dam
Publikováno v: Diabetes & Metabolism Journal, Vol 44, Iss 2, Pp 326-335 (2020)
Diabetes & Metabolism Journal
Diabetes and Metabolism Journal, 44(2), 326-335. KOREAN DIABETES ASSOC
Diabetes and Metabolism Journal, 44(2):e54, 326-335. Korean Diabetes Association
BACKGROUND: South Asians generally have an unfavourable metabolic phenotype compared with white Caucasians, including central obesity and insulin resistance. The Wnt protein family interacts with insulin signaling, and impaired Wnt signaling is assoc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e3c1d886df210b8010f304b257b7e2
http://e-dmj.org/upload/pdf/dmj-44-326.pdf
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4
TCF7L2 plays a complex role in human adipose progenitor biology, which might contribute to genetic susceptibility to type 2 diabetes
Autor: Manu Verma, Nellie Y. Loh, Rugivan Sabaratnam, Senthil K. Vasan, Andrea D. van Dam, Marijana Todorčević, Matthew J. Neville, Enrique Toledo, Fredrik Karpe, Constantinos Christodoulides
Publikováno v: Metabolism. 133:155240
Introduction Non-coding genetic variation at TCF7L2 is the strongest genetic determinant of type 2 diabetes (T2D) risk in humans. TCF7L2 encodes a transcription factor mediating the nuclear effects of WNT signaling in adipose tissue (AT). In vivo stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6131b6b3ecd9cea873be5e52650cd1cd
https://doi.org/10.1016/j.metabol.2022.155240
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5
Conditionally immortalized brown preadipocytes can switch between proliferative and differentiated states
Autor: Constantinos Christodoulides, Hetty C M Sips, Andrea D. van Dam, Sander Kooijman, Mariëtte R. Boon, Eline N. Kuipers, Jia Liu, Fredrik Karpe, Patrick C.N. Rensen, Guangqian Zhou, Jennifa C. Dorleijn, Antoine A.F. de Vries
Publikováno v: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. Elsevier
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 1864(12). ELSEVIER
Brown adipose tissue (BAT) is a potential target to treat cardiometabolic disorders because of its capacity to combust glucose and fatty acids for thermoregulation. Its cellular and molecular investigation in humans is hampered by the limited availab
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69aca2a190beab7dc6a04faa280604b6
https://doi.org/10.1016/j.bbalip.2019.08.007
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7
IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake
Autor: Eline N. Kuipers, Dov B. Ballak, Mariëtte R. Boon, Janna A. van Diepen, Charles A. Dinarello, Rinke Stienstra, Patrick C.N. Rensen, Ellemiek A. de Wit, Andrea D. van Dam
Publikováno v: International Journal of Molecular Sciences, 19, 2264
International Journal of Molecular Sciences, 19(8)
International Journal of Molecular Sciences
International Journal of Molecular Sciences 19 (2018) 8
Volume 19
Issue 8
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2264 (2018)
International Journal of Molecular Sciences, 19, 8, pp. 2264
The human cytokine interleukin (IL)-37 is an anti-inflammatory member of the IL-1 family of cytokines. Transgenic expression of IL-37 in mice protects them from diet-induced obesity and associated metabolic complications including dyslipidemia, infla
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c301bdbe798011858de3a767802fcd76
http://hdl.handle.net/2066/201390
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8
Quercetin lowers plasma triglycerides accompanied by white adipose tissue browning in diet-induced obese mice
Autor: Mariëtte R. Boon, Andrea D. van Dam, Patrick C.N. Rensen, Riekelt H. Houtkooper, Ntsiki M. Held, Isabel M. Mol, Eline N. Kuipers
Publikováno v: International journal of molecular sciences, 19(6):1786. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1786 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 19(6)
Volume 19
Issue 6
Obesity and dyslipidemia are major risk factors for the development of cardiovascular diseases (CVD). Quercetin, a natural flavonoid, lowers plasma triglycerides (TG) in human intervention studies, and its intake is associated with lower CVD risk. Th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3152a7511a0ce09dd22c14610c8bd04a
https://pure.amc.nl/en/publications/quercetin-lowers-plasma-triglycerides-accompanied-by-white-adipose-tissue-browning-in-dietinduced-obese-mice(1651b7e6-3c9e-4ddc-9f16-ebd8ddc00192).html
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9
Targeting white, brown and perivascular adipose tissue in atherosclerosis development
Autor: Patrick C.N. Rensen, Vanessa van Harmelen, Jimmy F.P. Berbée, Andrea D. van Dam, Mariëtte R. Boon
Publikováno v: European Journal of Pharmacology, 816, 82-92
Obesity is a well-established risk factor for atherosclerosis. However, the mechanistic link between accumulation of adipose tissue and development of atherosclerosis is not clear. Adipose tissue comprises various depots including white adipose tissu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de13ccb178a79f0b7a6f982b102d3d6
https://hdl.handle.net/1887/94834
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10
FcRγ-chain deficiency reduces the development of diet-induced obesity
Autor: Vanessa van Harmelen, J. Sjef Verbeek, Sander Kooijman, Patrick C.N. Rensen, Ko Willems van Dijk, Saeed Katiraei, Frits Koning, Irene O.C.M. Vroegrijk, Lianne van Beek, Mattijs M. Heemskerk, Andrea D. van Dam
Publikováno v: Obesity. 23:2435-2444
Objective Pathogenic immunoglobulins are produced during the development of obesity and contribute to the development of insulin resistance (IR). However, the mechanisms by which these antibodies affect IR are largely unknown. This study investigated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9628ba52e3d69aaf8067f39751498dd5
https://doi.org/10.1002/oby.21309
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