Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Andrea Dörner"'
Autor:
Marco Witkowski, Mario Witkowski, Mona Saffarzadeh, Julian Friebel, Termeh Tabaraie, Loc Ta Bao, Aritra Chakraborty, Andrea Dörner, Bernd Stratmann, Diethelm Tschoepe, Samantha J. Winter, Andreas Krueger, Wolfram Ruf, Ulf Landmesser, Ursula Rauch
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-12 (2020)
Abstract Background Diabetes mellitus is characterized by chronic vascular inflammation leading to pathological expression of the thrombogenic full length (fl) tissue factor (TF) and its isoform alternatively-spliced (as) TF. Blood-borne TF promotes
Externí odkaz:
https://doaj.org/article/60d317ddf20542a7866b9e1ffa241d12
Autor:
Marco Witkowski, Termeh Tabaraie, Daniel Steffens, Julian Friebel, Andrea Dörner, Carsten Skurk, Mario Witkowski, Bernd Stratmann, Diethelm Tschoepe, Ulf Landmesser, Ursula Rauch
Publikováno v:
Cardiovascular Diabetology, Vol 17, Iss 1, Pp 1-11 (2018)
Abstract Background Diabetes mellitus is characterized by chronic vascular disorder and presents a main risk factor for cardiovascular mortality. In particular, hyperglycaemia and inflammatory cytokines induce vascular circulating tissue factor (TF)
Externí odkaz:
https://doaj.org/article/bfaaf58c38c94a8ab35838e4a40faf5f
Autor:
Julian Friebel, Eileen Moritz, Marco Witkowski, Kai Jakobs, Elisabeth Strässler, Andrea Dörner, Daniel Steffens, Marianna Puccini, Stella Lammel, Rainer Glauben, Franziska Nowak, Nicolle Kränkel, Arash Haghikia, Verena Moos, Heinz-Peter Schutheiss, Stephan B. Felix, Ulf Landmesser, Bernhard H. Rauch, Ursula Rauch
Publikováno v:
Cells, Vol 10, Iss 12, p 3517 (2021)
Background: Protease-activated receptor 1 (PAR1) and toll-like receptors (TLRs) are inflammatory mediators contributing to atherogenesis and atherothrombosis. Vorapaxar, which selectively antagonizes PAR1-signaling, is an approved, add-on antiplatele
Externí odkaz:
https://doaj.org/article/c8594175c3e34c72945b83a56f22566c
Autor:
Andrea Dörner, Oleg Lynetskiy, Gerhild Euler, Ulf Landmesser, Klaus-Dieter Schlüter, Jacqueline Heger
Publikováno v:
Membranes, Vol 11, Iss 11, p 836 (2021)
Reperfusion is the only feasible therapy following myocardial infarction, but reperfusion has been shown to damage mitochondrial function and disrupt energy production in the heart. Adenine nucleotide translocase 1 (ANT1) facilitates the transfer of
Externí odkaz:
https://doaj.org/article/d4f416391d3e4ca0854d6ee3bdf84e29
Autor:
Fatih Yergöz, Julian Friebel, Nicolle Kränkel, Ursula Rauch-Kroehnert, Heinz-Peter Schultheiss, Ulf Landmesser, Andrea Dörner
Publikováno v:
Cells, Vol 10, Iss 8, p 2130 (2021)
Adenine nucleotide translocase 1 (ANT1) transfers ATP and ADP over the mitochondrial inner membrane and thus supplies the cell with energy. This study analyzed the role of ANT1 in the immune response of ischemic heart tissue. Ischemic ANT1 overexpres
Externí odkaz:
https://doaj.org/article/1d0652c371f84dd6947cb96886023ed4
Autor:
Ursula Rauch-Kroehnert, Ulf Landmesser, Andrea Dörner, Julian Friebel, Heinz-Peter Schultheiss, Nicolle Kränkel, Fatih Yergoz
Publikováno v:
Cells
Cells, Vol 10, Iss 2130, p 2130 (2021)
Volume 10
Issue 8
Cells, Vol 10, Iss 2130, p 2130 (2021)
Volume 10
Issue 8
Adenine nucleotide translocase 1 (ANT1) transfers ATP and ADP over the mitochondrial inner membrane and thus supplies the cell with energy. This study analyzed the role of ANT1 in the immune response of ischemic heart tissue. Ischemic ANT1 overexpres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28469df968078575bfb9986302449732
https://pubmed.ncbi.nlm.nih.gov/34440901
https://pubmed.ncbi.nlm.nih.gov/34440901
Autor:
Julian Friebel, Ursula Rauch, Sinah Grabitz, Marco Witkowski, Lena Taghipour, Termeh Tabaraie, Ulf Landmesser, Andrea Dörner, Bernd Stratmann, Diethelm Tschoepe, Kai Jakobs
Publikováno v:
Cardiovascular Drugs and Therapy
Purpose Metformin is the first-line antidiabetic drug and shown to reduce cardiovascular risk independent from its glucose lowering action. Particularly in poorly controlled diabetes, tissue factor (TF) is expressed in the vasculature and accounts fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a441667ee0c7799da41a5879eb8c62
Autor:
Dirk Westermann, Carsten Tschöpe, Ursula Rauch, Ulf Landmesser, Heinz-Peter Schultheiss, Andrea Dörner, Inga Klumpe, Konstantinos Savvatis
Publikováno v:
Journal of Molecular Medicine. 94:645-653
Ischemia impairs the adenine nucleotide translocase (ANT), which transports ADP and ATP across the inner mitochondrial membrane. We investigated whether ANT1 overexpression has protective effects on ischemic hearts. Myocardial infarction was induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d6cb762cd5b6d451129af1a94dc79e
https://doi.org/10.1007/s00109-016-1413-4
https://doi.org/10.1007/s00109-016-1413-4
Autor:
Bernhard H. Rauch, Konstantinos Savvatis, Peter Bobbert, Ursula Rauch, Verena Moos, Carsten Tschöpe, Michael Gotthardt, Dirk Lassner, Heinz-Peter Schutheiss, Marco Witkowski, Stephan B. Felix, Termeh Tabaraie, Andrea Dörner, Alice Weithauser, Michael H. Radke, Max Wegner, Ulf Landmesser, Julian Friebel, Mario Kasner, Diana Bösel
Publikováno v:
European heart journal. 40(40)
Aims Heart failure with preserved ejection fraction (HFpEF) and pathological cardiac aging share a complex pathophysiology, including extracellular matrix remodelling (EMR). Protease-activated receptor 2 (PAR2) deficiency is associated with EMR. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860c2d48e5f69e3fa2676778394d38f7
https://pubmed.ncbi.nlm.nih.gov/31324909
https://pubmed.ncbi.nlm.nih.gov/31324909
Autor:
Termeh Tabaraie, Ulf Landmesser, Wolfram Ruf, M Saffarzadeh, Julian Friebel, U Rauch-Kroehnert, Mario Witkowski, Bernd Stratmann, Diethelm Tschoepe, Marco Witkowski, Andrea Dörner, L Ta Bao
Publikováno v:
European Heart Journal. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a6b3c33789c0e2cbc6e8b668047a496
https://doi.org/10.1093/eurheartj/ehy566.p6558
https://doi.org/10.1093/eurheartj/ehy566.p6558