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pro vyhledávání: '"Andrea Cristina Gomes Pires"'
Autor:
Andrea Cristina Gomes Pires
Publikováno v:
Biblioteca Digital de Teses e Dissertações da UFMGUniversidade Federal de Minas GeraisUFMG.
The toxin Tx3-1 purified from the spider venom Phoneutria nigriventer is a blocker of potassium channels with great pharmacological potential. However the purification of the toxin from Phoneutria nigriventer crude venom is a long and expensive proce
Externí odkaz:
http://hdl.handle.net/1843/CMFC-7FJQUJ
Autor:
Ricardo F. Lima, Vânia F. Prado, Andrea Cristina Gomes Pires, Silvia Guatimosim, Márcia N.M. Alves, Michael K. Richardson, Enéas Ricardo de Morais Gomes, Alvair P. Almeida, Marta N. Cordeiro, Denis D. Damasceno, Marco A. M. Prado, Christopher Kushmerick, Alexandre Barbosa Andrade, Anderson J. Ferreira, Marcus Vinicius Gomez
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 57(2)
In this study, we evaluated the effects of PhKv, a 4584 Da peptide isolated from the spider Phoneutria nigriventer venom, in the isolated rat heart and in isolated ventricular myocytes. Ventricular arrhythmias were induced by occlusion of the left an