Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andrea Colarusso"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8891 (2024)
Cyclin-dependent kinase-like 5 (CDKL5) is a serine/threonine protein kinase involved in human brain development and functioning. Mutations in CDKL5, especially in its catalytic domain, cause a severe developmental condition named CDKL5 deficiency dis
Externí odkaz:
https://doaj.org/article/16b61ca8b5574aeda46fb7e63c065e36
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-18 (2022)
Abstract Background A significant fraction of the human proteome is still inaccessible to in vitro studies since the recombinant production of several proteins failed in conventional cell factories. Eukaryotic protein kinases are difficult-to-express
Externí odkaz:
https://doaj.org/article/81c57a9f01144251bf7bb7a29ffc4857
Autor:
Mohamed Boumaiza, Andrea Colarusso, Ermenegilda Parrilli, Elena Garcia-Fruitós, Angela Casillo, Anna Arís, Maria Michela Corsaro, Delia Picone, Serena Leone, Maria Luisa Tutino
Publikováno v:
Microbial Cell Factories, Vol 17, Iss 1, Pp 1-9 (2018)
Abstract Background Recent biotechnological advancements have allowed for the adoption of Lactococcus lactis, a typical component of starter cultures used in food industry, as the host for the production of food-grade recombinant targets. Among sever
Externí odkaz:
https://doaj.org/article/308b7286b0004c429c5adb8d32e264f3
Autor:
Marco Fondi, Stefano Gonzi, Mikolaj Dziurzynski, Paola Turano, Veronica Ghini, Marzia Calvanese, Andrea Colarusso, Concetta Lauro, Ermenegilda Parrilli, Maria Luisa Tutino
Publikováno v:
Metabolites, Vol 11, Iss 8, p 491 (2021)
hCDKL5 refers to the human cyclin-dependent kinase like 5 that is primarily expressed in the brain. Mutations in its coding sequence are often causative of hCDKL5 deficiency disorder, a devastating neurodevelopmental disorder currently lacking a cure
Externí odkaz:
https://doaj.org/article/4db893e695ef4f559a160a101cbcb545
Publikováno v:
Microorganisms, Vol 8, Iss 10, p 1466 (2020)
Our group has used the marine bacterium Pseudoalteromonas haloplanktis TAC125 (PhTAC125) as a platform for the successful recombinant production of “difficult” proteins, including eukaryotic proteins, at low temperatures. However, there is still
Externí odkaz:
https://doaj.org/article/88fc6804806743798b69d4180d48e26c
Autor:
Andrea Colarusso, Zaira Maroccia, Ermenegilda Parrilli, Elena Angela Pia Germinario, Andrea Fortuna, Stefano Loizzo, Laura Ricceri, Maria Luisa Tutino, Carla Fiorentini, Alessia Fabbri
Publikováno v:
Toxins, Vol 12, Iss 5, p 291 (2020)
Among gliomas, primary tumors originating from glial cells, glioblastoma (GBM) identified as WHO grade IV glioma, is the most common and aggressive malignant brain tumor. We have previously shown that the Escherichia coli protein toxin cytotoxic necr
Externí odkaz:
https://doaj.org/article/9d1b37275d5b425d85e0c78158ae8fb1
Autor:
Marzia Calvanese, Cecilia Balestra, Andrea Colarusso, Concetta Lauro, Christopher Riccardi, Marco Fondi, Ermenegilda Parrilli, Maria Luisa Tutino
Publikováno v:
Applied Microbiology and Biotechnology. 107:2469-2481
Abstract The Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 (PhTAC125) is considered an interesting alternative host for the recombinant protein production, that can be explored when the conventional bacterial expression systems fail. Inde
Autor:
Marzia, Calvanese, Andrea, Colarusso, Concetta, Lauro, Ermenegilda, Parrilli, Maria Luisa, Tutino
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2406
The Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 is an unconventional protein production host displaying a notable proficiency in the soluble production of difficult proteins, especially of human origin. Furthermore, the accumulation of
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618585
The Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 is an unconventional protein production host displaying a notable proficiency in the soluble production of difficult proteins, especially of human origin. Furthermore, the accumulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71aea65f8a1071399c133fd6d76958d
http://hdl.handle.net/11588/877482
http://hdl.handle.net/11588/877482
Autor:
Marzia Calvanese, Mikolaj Dziurzynski, Marco Fondi, Concetta Lauro, Stefano Gonzi, Ermenegilda Parrilli, Andrea Colarusso, Veronica Ghini, Paola Turano, Maria Luisa Tutino
Publikováno v:
Metabolites
Volume 11
Issue 8
Metabolites, Vol 11, Iss 491, p 491 (2021)
Volume 11
Issue 8
Metabolites, Vol 11, Iss 491, p 491 (2021)
hCDKL5 refers to the human cyclin-dependent kinase that is primarily expressed in the brain where it exerts its function in several neuron districts. Mutations in its coding sequence are often causative of hCDKL5 deficiency disorder. The large-scale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a02c93fafdeb40080ae37079943f431
https://doi.org/10.1101/2021.06.17.448472
https://doi.org/10.1101/2021.06.17.448472