Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Andrea Chobrutskiy"'
Autor:
Nagehan Pakasticali, Andrea Chobrutskiy, Dhruv N. Patel, Monica Hsiang, Saif Zaman, Konrad J. Cios, George Blanck, Boris I. Chobrutskiy
Publikováno v:
Cancer Informatics, Vol 22 (2023)
Introduction: One of the most pressing goals for cancer immunotherapy at this time is the identification of actionable antigens. Methods: This study relies on the following considerations and approaches to identify potential breast cancer antigens: (
Externí odkaz:
https://doaj.org/article/e21da741804642b483c70329929599a7
Autor:
Miguel A. Arias, Konrad J. Cios, Dorottya B. Kacsoh, Bailey E. Montgomery, Joanna J. Song, Anishaa R. Patel, Andrea Chobrutskiy, Boris I. Chobrutskiy, George Blanck
Publikováno v:
Biology, Vol 12, Iss 4, p 575 (2023)
Introduction. Glioblastoma (GBM) is the most aggressive primary brain tumor in adults. Despite a growing understanding of glioblastoma pathology, the prognosis remains poor. Methods. In this study, we used a previously extensively benchmarked algorit
Externí odkaz:
https://doaj.org/article/27cc0c186a9f4d448cf8d023a6ce5641
Autor:
Rachel A. Eakins, Andrea Chobrutskiy, Jamie K. Teer, Dhruv N. Patel, Monica Hsiang, Taha I. Huda, Saif Zaman, Wade J. Sexton, Domenico Coppola, Shayan Falasiri, George Blanck, Boris I. Chobrutskiy
Publikováno v:
Molecular Immunology. 150:58-66
Cancer testis antigens have been of interest as possible targets for cancer immunotherapies. To better understand the opportunities for the use of such immunotherapy targets, we used a chemical complementarity scoring algorithm and an original web to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2dafbe5862d88e8a643f8f309d4620
https://doi.org/10.1016/j.molimm.2022.08.001
https://doi.org/10.1016/j.molimm.2022.08.001
Autor:
Dorottya B. Kacsoh, Dhruv N. Patel, Monica Hsiang, Etienne C. Gozlan, Andrea Chobrutskiy, Boris I. Chobrutskiy, George Blanck
Publikováno v:
Journal of Molecular Neuroscience. 72:2011-2019
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc640a5d2461b47513eab39d7b2ee287
https://doi.org/10.1007/s12031-022-02050-6
https://doi.org/10.1007/s12031-022-02050-6
Autor:
Taha I. Huda, Michael J. Diaz, Etienne C. Gozlan, Andrea Chobrutskiy, Boris I. Chobrutskiy, George Blanck
Publikováno v:
Journal of Alzheimer's Disease. 88:619-629
Background: Despite the fact that only modest adaptive immune system related approaches to treating Alzheimer’s disease (AD) are available, an immunogenomics approach to the study of AD has not yet substantially advanced. Objective: Thus, we sought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e82311e2c5d3cbfa7168b09f673f87
https://doi.org/10.3233/jad-220119
https://doi.org/10.3233/jad-220119
Chemical features of melanoma tumor resident TRG CDR3s associated with better survival probabilities
Autor:
Deo Rei L. Agnila, Taha I. Huda, Rachel A. Eakins, Dhruv N. Patel, Monica Hsiang, Andrea Chobrutskiy, Boris I. Chobrutskiy, George Blanck
Publikováno v:
Melanoma Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e912755febf184ca16666a64bd10ab5
https://doi.org/10.1097/cmr.0000000000000899
https://doi.org/10.1097/cmr.0000000000000899
Autor:
Jacob C Kinskey, Taha I Huda, Etienne C Gozlan, Jessica U Quach, Juan F Arturo, Andrea Chobrutskiy, Boris I Chobrutskiy, George Blanck
Publikováno v:
Carcinogenesis.
The association between pancreatic adenocarcinoma (PAAD) and the pancreatic microbiome is not fully understood, although bacteria may decrease the effectiveness of chemotherapy and lead to anti-apoptotic, pro-inflammatory-microenvironments. To better
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ca94123694983d643ad21ef2ae2458e
https://doi.org/10.1093/carcin/bgad033
https://doi.org/10.1093/carcin/bgad033
Autor:
SUHAAS R. MANDALA, ALEXIS J. THOMSON, ETIENNE C. GOZLAN, DHRUV N. PATEL, ANDREA CHOBRUTSKIY, BORIS I. CHOBRUTSKIY, GEORGE BLANCK
Publikováno v:
Cancer Genomics Proteomics
Background/Aim: The recombination of V, D, and J immunoglobulin (IG) gene segments leads to many variations in the amino acids (AAs) encoded at that site, the complementarity determining region-3 (CDR3). Thus, cancer patients may have varying degrees
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d975c140720acc26d2bbcb3a770935
https://europepmc.org/articles/PMC10148069/
https://europepmc.org/articles/PMC10148069/
Autor:
Anishaa R. Patel, Dhruv N. Patel, Yaping N. Tu, Michelle Yeagley, Andrea Chobrutskiy, Boris I. Chobrutskiy, George Blanck
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-9
The evaluation of physicochemical characteristics of extensive adaptive immune receptor (IR) recombination sequence collections has led to the discovery of many correlations of those sequences and a variety of diseases, including cancer. In the cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c31b3183f26fe488c5310aa503888a
https://doi.org/10.1080/07391102.2022.2070546
https://doi.org/10.1080/07391102.2022.2070546
Autor:
Vayda R. Barker, Mallika Varkhedi, Dhruv N. Patel, Monica Hsiang, Andrea Chobrutskiy, Boris I. Chobrutskiy, George Blanck
Publikováno v:
American Journal of Reproductive Immunology. 89
Ovarian cancer continues to present significant challenges for early detection and treatment, indicating a need for novel approaches to improve disease outcomes. In this report, we applied a previously described algorithm for detecting chemical compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926153847e1c0956782ead4d28d6fc60
https://doi.org/10.1111/aji.13639
https://doi.org/10.1111/aji.13639