Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Andrea C. Ewald"'
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Akademický článek
Prior Hypoxia Exposure Enhances Murine Microglial Inflammatory Gene Expression in vitro Without Concomitant H3K4me3 Enrichment
Autor: Elizabeth A. Kiernan, Andrea C. Ewald, Jonathan N. Ouellette, Tao Wang, Abiye Agbeh, Andrew O. Knutson, Avtar S. Roopra, Jyoti J. Watters
Publikováno v: Frontiers in Cellular Neuroscience, Vol 14 (2020)
Hypoxia (Hx) is a component of multiple disorders, including stroke and sleep-disordered breathing, which often precede or are comorbid with neurodegenerative diseases. However, little is known about how hypoxia affects the ability of microglia, resi
Externí odkaz: https://doaj.org/article/f463f2fae277427f9d6f4e69cad1a948
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2
Akademický článek
Alzheimer’s Disease, Sleep Disordered Breathing, and Microglia: Puzzling out a Common Link
Autor: Tyler K. Ulland, Andrea C. Ewald, Andrew O. Knutson, Kaitlyn M. Marino, Stephanie M. C. Smith, Jyoti J. Watters
Publikováno v: Cells, Vol 10, Iss 11, p 2907 (2021)
Sleep Disordered Breathing (SDB) and Alzheimer’s Disease (AD) are strongly associated clinically, but it is unknown if they are mechanistically associated. Here, we review data covering both the cellular and molecular responses in SDB and AD with a
Externí odkaz: https://doaj.org/article/4f95946fd33740389127b7fe8b7aaba2
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5
A feature of maternal sleep apnea during gestation causes autism-relevant neuronal and behavioral phenotypes in offspring
Autor: Amanda M. Vanderplow, Bailey A. Kermath, Cassandra R. Bernhardt, Kimberly T. Gums, Erin N. Seablom, Abigail B. Radcliff, Andrea C. Ewald, Mathew V. Jones, Tracy L. Baker, Jyoti J. Watters, Michael E. Cahill
Publikováno v: PLoS Biology
PLoS Biology, Vol 20, Iss 2, p e3001502 (2022)
Mounting epidemiologic and scientific evidence indicates that many psychiatric disorders originate from a complex interplay between genetics and early life experiences, particularly in the womb. Despite decades of research, our understanding of the p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a57c6345df144a423192f9dfa09f27
https://pubmed.ncbi.nlm.nih.gov/35113852
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6
Sex- and Region-Specific Differences in the Transcriptomes of Rat Microglia from the Brainstem and Cervical Spinal Cord
Autor: Rebecca R Timko, Tracy L. Baker, Jyoti J. Watters, Avtar Roopra, Elizabeth Kiernan, Abigail B. Radcliff, Andrea C Ewald
Publikováno v: J Pharmacol Exp Ther
The neural control system underlying breathing is sexually dimorphic with males being more vulnerable to dysfunction. Microglia also display sex differences, and their role in the architecture of brainstem respiratory rhythm circuitry and modulation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e589c58217da4b61ae514d3d95637a
https://pubmed.ncbi.nlm.nih.gov/32661056
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7
Prior hypoxia exposure enhances murine microglial inflammatory gene expressionin vitrowithout concomitant H3K4me3 enrichment
Autor: Jonathan N. Ouellette, Abiye Agbeh, T. Wang, Andrea C Ewald, Jyoti J. Watters, Elizabeth Kiernan, Avtar Roopra
Hypoxia is a component of multiple disorders, including stroke and sleep-disordered breathing, that often precede or are comorbid with neurodegenerative diseases. However, little is known about how hypoxia affects the ability of microglia, resident C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8433b2b5f89ae7ba5987d7c15ecf2bb7
https://doi.org/10.1101/2020.02.03.933028
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