Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Andrea C. Carpenter"'
Autor:
Jia Nie, Andrea C. Carpenter, Laura B. Chopp, Ting Chen, Mariah Balmaceno-Criss, Thomas Ciucci, Qi Xiao, Michael C. Kelly, Dorian B. McGavern, Yasmine Belkaid, Rémy Bosselut
Publikováno v:
Nat Immunol
TCRαβ+ CD8α+ CD8β− intraepithelial lymphocytes (CD8αα IEL) differentiate from thymic IEL precursors (IELp) and contribute to gut homeostasis. However, their development remains poorly understood. Here we show that the zinc finger transcriptio
Publikováno v:
T-Cell Development ISBN: 9781071627396
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6674b0a32cfbfc601a65ff5ceba5fca2
https://doi.org/10.1007/978-1-0716-2740-2_8
https://doi.org/10.1007/978-1-0716-2740-2_8
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2580
Many analytical or cell culture procedures require homogeneous starting cell populations that cannot be obtained directly from organ dissection. Here, we describe two enrichment procedures to achieve this goal and discuss their respective advantages
Autor:
William G. Telford, Hellmut Merkle, Francis A. Flomerfelt, Martin J. Lizak, Michael Eckhaus, Rémy Bosselut, Nataliya P. Buxbaum, Ehydel Castro, Liliane M. dos Santos, Yasmine Belkaid, Veena Kapoor, Andrea C. Carpenter, Natella Maglakelidze, Nicolas Bouladoux, Catherine V. Bare, Ronald E. Gress, Brittany Oliver, Gregory Swan, Donald Eugene Farthing
Publikováno v:
JCI Insight. 2
Hematopoietic stem cell transplantation (HSCT) offers a cure for cancers that are refractory to chemotherapy and radiation. Most HSCT recipients develop chronic graft-versus-host disease (cGVHD), a systemic alloimmune attack on host organs. Diagnosis
Autor:
Elizabeth A. Wohlfert, Andrea C. Carpenter, Melanie S. Vacchio, Yasmine Belkaid, Rémy Bosselut, Lie Wang, Nicolas Bouladoux, Paul E. Love, Yumei Xiong, Ki-Duk Song, Linus C. Williams
Publikováno v:
Nature immunology
The transcription factor ThPOK promotes CD4(+) T cell differentiation in the thymus. Here, using a mouse strain that allows post-thymic gene deletion, we show that ThPOK maintains CD4(+) T lineage integrity and couples effector differentiation to env
Publikováno v:
T-Cell Development ISBN: 9781493928088
In vitro culture is an important complement, or substitute, to in vivo approaches in order to study T cell effector differentiation. Here, we describe culture conditions that generate specific effector cell types by exposing naive T cells to appropri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dfde3afe086ba844926705b42c810d8
https://doi.org/10.1007/978-1-4939-2809-5_10
https://doi.org/10.1007/978-1-4939-2809-5_10
Publikováno v:
T-Cell Development ISBN: 9781493928088
Many analytical or cell culture procedures require homogeneous starting cell populations that cannot be obtained directly from organ dissection. Here, we describe two enrichment procedures to achieve this goal and discuss their respective advantages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e418f23d9be229c471b35751fd31b5e2
https://doi.org/10.1007/978-1-4939-2809-5_7
https://doi.org/10.1007/978-1-4939-2809-5_7
Autor:
Yumei Xiong, Marc K. Jenkins, Lai Wei, H. Hamlet Chu, Yasmine Belkaid, Liliane M. dos Santos, Shruti Naik, John J. O'Shea, Andrea C. Carpenter, John R. Grainger, Lie Wang, Rémy Bosselut, Yuka Kanno
Publikováno v:
Immunity. 37:622-633
SummaryT helper (Th) cells are critical for defenses against infection and recognize peptides bound to class II major histocompatibility complex (MHC II) molecules. Although transcription factors have been identified that direct Th cells into specifi
Autor:
Pin Zhang, Takashi Maruyama, Brian F. Zamarron, Wanjun Chen, Bradford Hall, Joanne E. Konkel, Rémy Bosselut, Andrea C. Carpenter, Ashok B. Kulkarni, Yumei Xiong
Publikováno v:
Nature immunology
The molecular mechanisms that direct the development of TCRαβ+CD8αα+ intestinal intraepithelial lymphocytes (IELs) are not thoroughly understood. Here we show that transforming growth factor-β (TGF-β) controls the development of TCRαβ+CD8αα
Autor:
Andrea C. Carpenter, Rémy Bosselut
Publikováno v:
Nature Immunology. 11:666-673
The development of T cells in the thymus involves several differentiation and proliferation events, during which hematopoietic precursors give rise to T cells ready to respond to antigen stimulation and undergo effector differentiation. This review a