Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Andrea C Cumino"'
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0007032 (2019)
The secretion of extracellular vesicles (EVs) in helminth parasites is a constitutive mechanism that promotes survival by improving their colonization and adaptation in the host tissue. In the present study, we analyzed the production of EVs from sup
Externí odkaz:
https://doaj.org/article/34c1c60ce3a0400eac0916aa972f95d9
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 11, p e0006111 (2017)
Cystic echinococcosis (CE) is a worldwide parasitic zoonosis caused by the larval stage of Echinococcus granulosus. Current chemotherapy against this disease is based on the administration of benzimidazoles (BZMs). However, BZM treatment has a low cu
Externí odkaz:
https://doaj.org/article/0a27493a7b4b4aa791892bb99a10a280
Autor:
Julia A Loos, Valeria A Dávila, Christian Rodriguez Rodrigues, Romina Petrigh, Jorge A Zoppi, Fernando A Crocenzi, Andrea C Cumino
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 3, p e0005474 (2017)
[This corrects the article DOI: 10.1371/journal.pntd.0005370.].
Externí odkaz:
https://doaj.org/article/18e17ab4111543c79d09a1009b809cd3
Autor:
Julia A Loos, Valeria A Dávila, Christian R Rodrígues, Romina Petrigh, Jorge A Zoppi, Fernando A Crocenzi, Andrea C Cumino
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005370 (2017)
Metformin (Met) is an anti-hyperglycemic and potential anti-cancer agent which may exert its anti-proliferative effects via the induction of energetic stress. In this study we investigated the in vitro and in vivo efficacy of Met against the larval s
Externí odkaz:
https://doaj.org/article/b9ee9b3b442b4a5bb90fa9087c00c813
Autor:
María Celeste Nicolao, Julia A Loos, Christian Rodriguez Rodrigues, Viviana Beas, Andrea C Cumino
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181528 (2017)
Cystic echinococcosis (CE) is a worldwide distributed helminthic zoonosis caused by Echinococcus granulosus. Benzimidazole derivatives are currently the only drugs for chemotherapeutic treatment of CE. However, their low efficacy and the adverse effe
Externí odkaz:
https://doaj.org/article/215ff09027c848318dedfe976e8e3b8b
Autor:
Julia A Loos, Andrea C Cumino
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126009 (2015)
Metformin (Met) is a biguanide anti-hyperglycemic agent, which also exerts antiproliferative effects on cancer cells. This drug inhibits the complex I of the mitochondrial electron transport chain inducing a fall in the cell energy charge and leading
Externí odkaz:
https://doaj.org/article/c63959dbdb194c6981dc79255eaaa510
Autor:
María Celeste Nicolao, Christian Rodriguez Rodrigues, Magalí B. Coccimiglio, Camila Ledo, Guillermo H. Docena, Andrea C. Cumino
Background Echinococcus granulosus sensu lato species complex, causing cystic echinococcosis in both humans and animals, represent one of the most widespread zoonoses of medical importance, which evolved manipulating the immune response of their host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ec29bbce320ca1d2e77c9a3866d3e0e
https://doi.org/10.21203/rs.3.rs-2693470/v1
https://doi.org/10.21203/rs.3.rs-2693470/v1
Autor:
Christian Rodriguez Rodrigues, Julia A. Loos, María Celeste Nicolao, Andrea C. Cumino, Magalí Coccimiglio
Publikováno v:
Parasitology. 149:138-144
Alveolar echinococcosis (AE) is a severe disease caused by Echinococcus multilocularis. Its chemotherapeutic treatment is based on benzimidazoles, which are rarely curative and cause several adverse effects. Therefore, it is necessary to develop alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387256b71c0f27a2c7de94471bd801dc
https://doi.org/10.1017/s0031182021001633
https://doi.org/10.1017/s0031182021001633
Autor:
María Celeste Nicolao, Natalia Pla, Christian Rodriguez Rodrigues, Mora Massaro, Andrea C. Cumino, Julia A. Loos, Maia Chop
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
1.AbstractImmune evasion is a hallmark of persistent echinococcal infection, comprising modulation of innate immune cells and antigen-specific T cell responses. However, recognition of Echinococcus granulosus by dendritic cells (DCs) is a key determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4e9fd1ab22a5531c20268d6102d875
https://doi.org/10.1038/s41598-021-96435-z
https://doi.org/10.1038/s41598-021-96435-z
Publikováno v:
Antimicrob Agents Chemother
Alveolar echinococcosis (AE) is a severe disease caused by the larval stage of the tapeworm Echinococcus multilocularis. Current chemotherapeutic treatment options based on benzimidazoles are of limited effectiveness, which underlines the need to fin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fba98c17d453d6656b0051af4f5df01
https://europepmc.org/articles/PMC7449199/
https://europepmc.org/articles/PMC7449199/