Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrea C, Itskovich"'
Autor:
Mir Jafer Ali, Andrea C. Itskovich, Robert M. Levy, Michael W. Vavra, Yot Navalitloha, Eric W.-Y. Kang, Dennis R. Groothuis, Peter Molnar
Publikováno v:
Neuro-Oncology. 8:109-118
A recurring question in the treatment of malignant brain tumors has been whether treatment failure is due to inadequate delivery or ineffective drugs. To isolate these issues, we tested a paradigm in which the "therapeutic" agent was a toxin about wh
Autor:
Howard L. Lipton, Dennis R. Groothuis, Kurt E. Schlageter, Michael W. Vavra, Cathleen V. Allen, Shannon Hertzler, Eric W.-Y. Kang, Andrea C. Itskovich
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 27(1)
We examined the roles of diffusion, convection and capillary transporters in solute removal from extracellular space (ECS) of the brain. Radiolabeled solutes (eight with passive distribution and four with capillary or cell transporters) were injected
Autor:
Mir J, Ali, Yot, Navalitloha, Michael W, Vavra, Eric W-Y, Kang, Andrea C, Itskovich, Peter, Molnar, Robert M, Levy, Dennis R, Groothuis
Publikováno v:
Neuro-oncology. 8(2)
A recurring question in the treatment of malignant brain tumors has been whether treatment failure is due to inadequate delivery or ineffective drugs. To isolate these issues, we tested a paradigm in which the "therapeutic" agent was a toxin about wh
Autor:
Cosmin Dobrescu, Sherman Ward, Robert M. Levy, Dennis R. Groothuis, Andrea C. Itskovich, Cynthia V. Dills, Cathleen V. Allen
Publikováno v:
Journal of neurosurgery. 90(2)
Object. The authors evaluated convection-enhanced delivery (CED) of 14C-sucrose to the rat brain as a method of enhancing cerebral drug delivery and compared it with intravenous (IV) and intraventricular (IVT) routes of administration.Methods. Groups
Autor:
Andrea C. Itskovich, Dennis R. Groothuis, Susan C. Schwerin, Sherman Ward, Cathleen V. Allen, Robert M. Levy, Cynthia V. Dills, Kurt E. Schlageter
Publikováno v:
Brain research. 803(1-2)
Blood-brain barrier (BBB) transcapillary transport was studied after insertion of cannulas and microdialysis probes into the brains of three groups of rats. Quantitative autoradiography was used to measure changes in BBB permeability around the inser