Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Andrea Buchacher"'
Autor:
Andrea Buchacher, John M. Curling
Immunoglobulin G is one of the most abundant proteins in plasma and is the leading product of the human plasma fractionation industry. The IgG content in plasma depends on the collection modus and the donation frequency. Typical plasma fractionation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f240ff1b91faa535f08c688fadfc20f2
https://doi.org/10.1016/b978-0-08-100623-8.00043-8
https://doi.org/10.1016/b978-0-08-100623-8.00043-8
Autor:
John W. Armando, E. Morrey Atkinson, Peter Bernhardt, Torbjörn S. Blank, Yvonne A. Brady, Eggert Brekkan, Andrea Buchacher, Karolina Busson, Maire H. Caparon, Enrique N. Carredano, Jeffrey R. Carter, Andreas Castan, Shuang Chen, Kenneth P. Clapp, Scott A. Cook, John T. Cundy, John M. Curling, Åke Danielsson, Kjell O. Eriksson, Alain Fairbank, Suzanne S. Farid, Simon Fischer, Kine A.-K. Frej, Parrish M. Galliher, Klaus Gebauer, Glen S. Giese, Alan Gilbert, Anna Grönberg, Albrecht Gröner, Robert S. Gronke, Martin Hall, Kim R. Hejnaes, Rachel S. Hendricks, Rolf A. Hjorth, Geoff Hodge, Matt H. Hutchinson, Günter Jagschies, Michael J. Jenkins, Mikael I. Johansson, John Joseph, Oliver Kaltenbrunner, Gautam Kapoor, Tomas M. Karlsson, Brian D. Kelley, Annika Kleinjans, Jashwant Kumar, Karol M. Łącki, Philip Lester, Jakob Liderfelt, Xin Xin Lin, Eva K. Lindskog, Mats Lundgren, Ratish Mangalath-Illam, Trevor J. Marshall, Joseph P. Martin, Krunal K. Mehta, Brian Montgomery, Daniel Nelson, Roger Nordberg, Dana A. Olson, Martin Östling, John P. Pieracci, David J. Pollard, Alain Pralong, Hari Pujar, Joost P. Quaadgras, Tom C. Ransohoff, Anurag S. Rathore, Craig Robinson, Jonathan Royce, Michael A. Rubacha, Henrik Sandegren, Andreas Schaubmar, Patrick Schulz, Sumit K. Singh, Stephen E. Sobacke, Sriram Srinivasan, Matthew J. Stork, Bruce S. Tangarone, Jorg Thommes, Matthew J. Traylor, Johan Tschöp, James M. Van Alstine, Johnson Varghese, Ganesh Vedantham, Thomas von Hirschheydt, William B. Wellborn, Till Wenger, Susanne Westin, David G. Westman, Matthew Westoby, William G. Whitford, Ambrose J. Williams, John M. Woodgate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ab37a02755962071e60b3fe89a67442
https://doi.org/10.1016/b978-0-08-100623-8.09990-4
https://doi.org/10.1016/b978-0-08-100623-8.09990-4
Publikováno v:
Journal of Membrane Science. 274:108-115
Small traces of aggregates may cause reduced stability of human immunoglobulin G preparations. Ultra-/diafiltration as last step before formulation could also contribute to aggregate formation or depletion. One of the key challenges is to find a sens
Autor:
Andrea Buchacher, Günter Iberer
Publikováno v:
Biotechnology Journal. 1:148-163
Plasma-derived intravenous immunoglobulin (IVIG) preparations have been successfully applied for the prophylactic prevention of infectious diseases in immunodeficient patients. In addition to its replacement therapy of primary and secondary antibody
Autor:
Sabine Greinstetter, Ingrid Pabinger, Andrea Buchacher, Jürgen Römisch, Alois Jungbauer, Eva-Maria Kopecky
Publikováno v:
Journal of Immunological Methods. 308:90-100
Epitope mapping using antibodies against factor VIII (FVIII) has been performed using blotting techniques with truncated and/or digested FVIII molecules. Here, we focused on the precise mapping of affinity purified IgG from patients with an immune re
Autor:
Ingrid Pabinger, Eva-Maria Kopecky, Sabine Greinstetter, Andrea Buchacher, Alois Jungbauer, Jürgen Römisch
Publikováno v:
Biotechnology and Bioengineering. 93:647-655
Peptides as therapeutic substances are efficient agents in the treatment of several diseases. However, they often have to be chemically modified in order to be suited as therapeutic agent. Conjugation to large carrier molecules is often required. A c
Publikováno v:
Journal of Chromatography A. 1043:41-46
In human immunoglobulin preparations with a concentration of 50 mg/ml aggregate formation below 0.3% is difficult to quantify. Such small traces may later be responsible for reduced stability and therefore this generation during the process must be p
Publikováno v:
Journal of Chromatography A. 1009:89-96
Large aggregates (Mr: 10(6)-10(7) g/mol) of human immunoglobulins are present in extremely small concentrations in IgG preparations (
Publikováno v:
Rapid Communications in Mass Spectrometry. 17:1815-1824
Methionine residues and the oxidised forms in proteins are becoming more and more important in view of their biological function. In particular, methionine sulfoxide seems to have a regulatory function. This paper presents a fast strategy for simulta
Publikováno v:
Journal of Chromatography A. 972:115-129
Preparative continuous annular chromatography, a method to separate proteins in a truly continuous manner, was investigated in an industrial environment. Plasma-derived clotting factor IX concentrate was used as model protein. Separation of vitronect