Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Andrea Brázdová"'
Autor:
Lydie Plecitá-Hlavatá, Andrea Brázdová, Monika Křivonosková, Cheng-Jun Hu, Tzu Phang, Jan Tauber, Min Li, Hui Zhang, Konrad Hoetzenecker, Slaven Crnkovic, Grazyna Kwapiszewska, Kurt R. Stenmark
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn pulmonary hypertension (PH), pulmonary arterial remodeling is often accompanied by perivascular inflammation. The inflammation is characterized by the accumulation of activated macrophages and lymphocytes within the adventitial stroma,
Externí odkaz:
https://doaj.org/article/1b0559c1faa0478e9a15680b503aa81a
Role of Mitochondrial Glycerol-3-Phosphate Dehydrogenase in Metabolic Adaptations of Prostate Cancer
Autor:
Alena Pecinová, Lukáš Alán, Andrea Brázdová, Marek Vrbacký, Petr Pecina, Zdeněk Drahota, Josef Houštěk, Tomáš Mráček
Publikováno v:
Cells, Vol 9, Iss 8, p 1764 (2020)
Prostate cancer is one of the most prominent cancers diagnosed in males. Contrasting with other cancer types, glucose utilization is not increased in prostate carcinoma cells as they employ different metabolic adaptations involving mitochondria as a
Externí odkaz:
https://doaj.org/article/2b1e842ab00b46398a0f710c72fa7212
Autor:
Gabriel Birkus, Miroslav Smola, Petra Břehová, Lubomír Rulíšek, Martin Maxmilian Kaiser, Michal Šála, Aleš Marek, Martin Dračínský, Andrea Brázdová, Barbora Novotna, Zlatko Janeba, Milan Dejmek, Joshua R. Smith, Markéta Pimková Polidarová, Radim Nencka, Ondřej Páv, Evzen Boura, Ondrej Gutten
Publikováno v:
Journal of Medicinal Chemistry. 64:7596-7616
Cyclic dinucleotides (CDNs) are second messengers that bind to the stimulator of interferon genes (STING) and trigger the expression of type I interferons and proinflammatory cytokines. Here we evaluate the activity of 3',3'-c-di(2'F,2'dAMP) and its
Role of Mitochondrial Glycerol-3-Phosphate Dehydrogenase in Metabolic Adaptations of Prostate Cancer
Autor:
Andrea Brázdová, Marek Vrbacký, Josef Houštěk, Lukáš Alán, Alena Pecinová, Zdeněk Drahota, Petr Pecina, Tomáš Mráček
Publikováno v:
Cells
Volume 9
Issue 8
Cells, Vol 9, Iss 1764, p 1764 (2020)
Volume 9
Issue 8
Cells, Vol 9, Iss 1764, p 1764 (2020)
Prostate cancer is one of the most prominent cancers diagnosed in males. Contrasting with other cancer types, glucose utilization is not increased in prostate carcinoma cells as they employ different metabolic adaptations involving mitochondria as a
Autor:
Zahra Aliakbar Tehrani, Martin Zavřel, Tomáš Jandušík, Andrea Brázdová, Ondrej Gutten, Radim Nencka, Gabriel Birkus, Miloš Buděšínský, Ondřej Páv, Evžen Bouřa, Markéta Pimková Polidarová, Barbora Novotna, Radek Liboska, Zdeněk Vavřina, Milan Dejmek, Miroslav Smola, Jiří Brynda, Ivan Štěpánek, Lubomír Rulíšek, Lenka Vaneková
Publikováno v:
Journal of medicinal chemistry. 62(23)
Cyclic dinucleotides are second messengers in the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, which plays an important role in recognizing tumor cells and viral or bacterial infections. They bind to the STING adapto
Autor:
Lukáš Alán, Kristýna Čunátová, Kateřina Tauchmannová, Marek Vrbacký, Petr Pecina, Josef Houštěk, Tomáš Mráček, Vilma Kaplanová, Hana Nůsková, Jan Elias, Jana Kovalčíková, Andrea Brázdová, Vladimír Kořínek, Radislav Sedlacek
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 33(12)
Biogenesis of F1Fo ATP synthase, the key enzyme of mitochondrial energy provision, depends on transmembrane protein 70 (TMEM70), localized in the inner mitochondrial membrane of higher eukaryotes. ...
Publikováno v:
BioFactors (Oxford, England)REFERENCES. 45(5)
Metformin is the most widely prescribed treatment of hyperglycemia and type II diabetes since 1970s. During the last 15 years, its popularity increased due to epidemiological evidence, that metformin administration reduces incidence of cancer. Howeve
Autor:
Claire Gérard, Marine Thébault, Baptiste Lamarthée, Coraline Genet, Florine Cattin, Andréa Brazdova, Nona Janikashvili, Claudie Cladière, Marion Ciudad, Séthi Ouandji, Thibault Ghesquière, Hélène Greigert, Claire Tinel, Olivier Adotevi, Philippe Saas, Maxime Samson, Sylvain Audia, Bernard Bonnotte
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Recently developed cell-based therapies have shown potential for graft-versus-host disease (GvHD) mitigation. Our team previously developed a protocol to generate human monocyte-derived suppressor Cells (HuMoSC), a subpopulation of CD33+ suppressor c
Externí odkaz:
https://doaj.org/article/d0bce2cc24f54a32bbc91216ac963b01
Publikováno v:
Methods and Protocols, Vol 5, Iss 5, p 70 (2022)
The liver is a complex organ that governs many types of metabolisms, including energy metabolism and other cellular processes. The liver also plays a crucial role in important functions in immunity, and the activity of liver tissue-associated immunit
Externí odkaz:
https://doaj.org/article/9932e0c24f134724a39e1453263dab88
Autor:
Nona Janikashvili, Claire Gérard, Marine Thébault, Andrea Brazdova, Clovis Boibessot, Claudie Cladière, Marion Ciudad, Hélène Greigert, Séthi Ouandji, Thibault Ghesquière, Maxime Samson, Sylvain Audia, Philippe Saas, Bernard Bonnotte
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Background Immunosuppressive cell-based therapy is a recent strategy for controlling Graft-versus-Host Disease (GvHD). Such cells ought to maintain their suppressive function in inflammatory conditions and in the presence of immunosuppressive agents
Externí odkaz:
https://doaj.org/article/54df80e585cd4c2b99648795a132b058