Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andrea Behrenswerth"'
Autor:
Christa E. Müller, Andrea Behrenswerth, Katarzyna Kieć-Kononowicz, Meryem Köse, Sabrina Gollos, Fabian Heisig, Vigneshwaran Namasivayam, Tadeusz Karcz, Amelie Fiene
Publikováno v:
Journal of Medicinal Chemistry. 61:4301-4316
Fluorescent ligands represent powerful tools for biological studies and are considered attractive alternatives to radioligands. In this study, we developed fluorescent antagonists for A2B adenosine receptors (A2BARs), which are targeted by antiasthma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d4c2c94ca8a0a1c7ff89ed20b2ec56
https://doi.org/10.1021/acs.jmedchem.7b01627
https://doi.org/10.1021/acs.jmedchem.7b01627
Autor:
Meryem, Köse, Sabrina, Gollos, Tadeusz, Karcz, Amelie, Fiene, Fabian, Heisig, Andrea, Behrenswerth, Katarzyna, Kieć-Kononowicz, Vigneshwaran, Namasivayam, Christa E, Müller
Publikováno v:
Journal of medicinal chemistry. 61(10)
Fluorescent ligands represent powerful tools for biological studies and are considered attractive alternatives to radioligands. In this study, we developed fluorescent antagonists for A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbee19ae03b715d3bc6f0938a92aba23
https://pubmed.ncbi.nlm.nih.gov/29681156
https://pubmed.ncbi.nlm.nih.gov/29681156
Autor:
Andrea Behrenswerth, Karen Nieber, Christa E. Müller, Ali El-Tayeb, Sebastian Michael, Sabrina Gollos, Aliaa Abdelrahman
Publikováno v:
ACS Medicinal Chemistry Letters. 2:890-895
Adenosine A2A receptor agonists for the local treatment of inflammatory bowel disease (IBS) were designed and synthesized. Polar groups were introduced to prevent peroral absorption and subsequent systemic, e.g., hypotensive, side effects. 4-(2-{6-Am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41a6b82abb0f285369d5ef9375e1d63
https://doi.org/10.1021/ml200189u
https://doi.org/10.1021/ml200189u
Autor:
Schrader J, Michael Romio, Christa E. Müller, Jamshed Iqbal, Herbert Zimmermann, Andrea Behrenswerth, Ali El-Tayeb, Marion Schneider
Publikováno v:
Journal of Medicinal Chemistry. 52:7669-7677
Prodrugs of adenosine A2A receptor agonists were developed that are activated by ecto-5′-nucleotidase (ecto-5′-NT, CD73). Because ecto-5′-NT is upregulated in inflamed tissue, the A2A agonists are expected to be released from their prodrug form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::146ec151b008c8cf889be12778553ef4
https://doi.org/10.1021/jm900538v
https://doi.org/10.1021/jm900538v
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:2842-2851
In the present study we synthesized 36 coumarin and 2H-chromene derivatives applying a recently developed umpoled domino reaction using substituted salicylaldehyde and alpha,beta-unsaturated aldehyde derivatives as starting compounds. In radioligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cec681d197e627ae54262697d594ff
https://doi.org/10.1016/j.bmc.2009.02.027
https://doi.org/10.1016/j.bmc.2009.02.027
Autor:
Tadeusz Karcz, Sonja Hinz, Maria Kaleta, Andrea Behrenswerth, K. Atzler, Dominik Thimm, Viktor Rempel, Clara T. Schoeder, Katarzyna Kieć-Kononowicz, Christa E. Müller
GPR18 and GPR55 are orphan G protein-coupled receptors (GPCRs) that interact with certain cannabinoid (CB) receptor ligands. In the present study bicyclic imidazole-4-one derivatives were discovered as new scaffolds for the development of antagonists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b29106adbe9fb132d21f3d84d3e75b
https://ruj.uj.edu.pl/xmlui/handle/item/106890
https://ruj.uj.edu.pl/xmlui/handle/item/106890
Autor:
Ali, El-Tayeb, Jamshed, Iqbal, Andrea, Behrenswerth, Michael, Romio, Marion, Schneider, Herbert, Zimmermann, Jürgen, Schrader, Christa E, Müller
Publikováno v:
Journal of medicinal chemistry. 52(23)
Prodrugs of adenosine A(2A) receptor agonists were developed that are activated by ecto-5'-nucleotidase (ecto-5'-NT, CD73). Because ecto-5'-NT is upregulated in inflamed tissue, the A(2A) agonists are expected to be released from their prodrug form a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d153178885d2f71abd30547ab0f375e
https://pubmed.ncbi.nlm.nih.gov/19580286
https://pubmed.ncbi.nlm.nih.gov/19580286
Autor:
Ali El-Tayeb, Jamshed Iqbal, Andrea Behrenswerth, Michael Romio, Marion Schneider, Herbert Zimmermann, Jürgen Schrader, Christa E. Müller
Publikováno v:
Journal of Medicinal Chemistry; Dec2009, Vol. 52 Issue 23, p7669-7677, 9p