Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrea Beaghton"'
Autor:
Chrysanthi Taxiarchi, Andrea Beaghton, Nayomi Illansinhage Don, Kyros Kyrou, Matthew Gribble, Dammy Shittu, Scott P. Collins, Chase L. Beisel, Roberto Galizi, Andrea Crisanti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Technologies that can halt the spread of gene drives would be highly useful in controlling or reverting their effect. Here the authors use the anti-CRISPR protein AcrIIA4 to inactivate drives in A. gambiae.
Externí odkaz:
https://doaj.org/article/d5874a5ae9a2467ba0f3206162213461
Autor:
Andrew Hammond, Xenia Karlsson, Ioanna Morianou, Kyros Kyrou, Andrea Beaghton, Matthew Gribble, Nace Kranjc, Roberto Galizi, Austin Burt, Andrea Crisanti, Tony Nolan
Publikováno v:
PLoS Genetics, Vol 17, Iss 1, p e1009321 (2021)
Homing-based gene drives use a germline source of nuclease to copy themselves at specific target sites in a genome and bias their inheritance. Such gene drives can be designed to spread and deliberately suppress populations of malaria mosquitoes by i
Externí odkaz:
https://doaj.org/article/ac0bcc630588492db284e4b52ca9113f
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-14 (2017)
Abstract Background The introduction of new malaria control interventions has often led to the evolution of resistance, both of the parasite to new drugs and of the mosquito vector to new insecticides, compromising the efficacy of the interventions.
Externí odkaz:
https://doaj.org/article/8cddd7f047c04bb48f60e7cf781696fb
Autor:
Tony Nolan, Matthew Gribble, Chrysanthi Taxiarchi, Andrea Crisanti, Dario Meacci, Roberto Galizi, Andrew Hammond, Andrea Beaghton, Kyros Kyrou, Giulia Morselli, Alekos Simoni, Austin Burt
Publikováno v:
Nature Biotechnology
Only female insects transmit diseases such as malaria, dengue and Zika; therefore, control methods that bias the sex ratio of insect offspring have long been sought. Genetic elements such as sex-chromosome drives can distort sex ratios to produce uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d0590cc4bc0ae78f1abfded9421d6c
https://doi.org/10.1038/s41587-020-0508-1
https://doi.org/10.1038/s41587-020-0508-1
Autor:
Nayomi Illansinhage Don, Scott P. Collins, Roberto Galizi, Andrea Crisanti, Chrysanthi Taxiarchi, Chase L. Beisel, Matthew Gribble, Andrea Beaghton, Dammy Shittu, Kyros Kyrou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature communications
England
Nature Communications
Nature communications
England
Nature Communications
CRISPR-based gene drives offer promising means to reduce the burden of pests and vector-borne diseases. These techniques consist of releasing genetically modified organisms carrying CRISPR-Cas nucleases designed to bias their inheritance and rapidly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518983bd4d119df8c955dc2ea81fe3c9
https://doi.org/10.1038/s41467-021-24214-5
https://doi.org/10.1038/s41467-021-24214-5
Autor:
Andrea Crisanti, Ioanna Morianou, Tony Nolan, Nace Kranjc, Andrew Hammond, Kyros Kyrou, Matthew Gribble, Roberto Galizi, Andrea Beaghton, Xenia Karlsson, Austin Burt
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 1, p e1009321 (2021)
PLoS Genetics, Vol 17, Iss 1, p e1009321 (2021)
Homing-based gene drives use a germline source of nuclease to copy themselves at specific target sites in a genome and bias their inheritance. Such gene drives can be designed to spread and deliberately suppress populations of malaria mosquitoes by i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ae0c80541b973c1a7ea2dc87d85310
https://eprints.keele.ac.uk/9143/1/journal.pgen.1009321.pdf
https://eprints.keele.ac.uk/9143/1/journal.pgen.1009321.pdf
Autor:
Dario Meacci, Matthew Gribble, Alekos Simoni, Austin Burt, Chrysanthi Taxiarchi, Kyros Kyrou, Andrea Crisanti, Andrew Hammond, Giulia Morselli, Andrea Beaghton, Tony Nolan, Roberto Galizi
Publikováno v:
Nature Biotechnology
Only female insects transmit diseases such as malaria, dengue and Zika; therefore, control methods that bias the sex ratio of insect offspring have long been sought. Genetic elements such as sex-chromosome drives can distort sex ratios to produce uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22eccf7998bd5cd7bd1ea6526447a444
https://eprints.keele.ac.uk/8578/1/s41587-020-0658-1.pdf
https://eprints.keele.ac.uk/8578/1/s41587-020-0658-1.pdf
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-14 (2017)
Malaria Journal
Malaria Journal
Background The introduction of new malaria control interventions has often led to the evolution of resistance, both of the parasite to new drugs and of the mosquito vector to new insecticides, compromising the efficacy of the interventions. Recent pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8915a17d06669174ec123b719e1c9ad7
http://link.springer.com/article/10.1186/s12936-017-1932-7
http://link.springer.com/article/10.1186/s12936-017-1932-7
Autor:
Tony Nolan, Andrew Hammond, Andrea Beaghton, H. Charles J. Godfray, Austin Burt, Andrea Crisanti
Publikováno v:
Genetics
There is a need for new interventions against the ongoing burden of vector-borne diseases such as malaria and dengue. One suggestion has been to develop genes encoding effector molecules that block parasite development within the vector, and then use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb16fc24ea389ba100fba829b27281f
https://doi.org/10.1534/genetics.116.197632
https://doi.org/10.1534/genetics.116.197632
Publikováno v:
Proceedings of the Royal Society B: Biological Sciences
Gene drive is a natural process of biased inheritance that, in principle, could be used to control pest and vector populations. As with any form of pest control, attention should be paid to the possibility of resistance evolving. For nuclease-based g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7db3a4a8bd0d3e05776f4625f341f20
http://hdl.handle.net/10044/1/74322
http://hdl.handle.net/10044/1/74322