Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrea Baldocchi Pizzo"'
Autor:
Andréia Cristina Karklin Fontana, Joaquim Coutinho-Netto, Luciana R. de Oliveira, Antonio Miranda, Wagner Ferreira dos Santos, Rene Oliveira Beleboni, Andrea Baldocchi Pizzo, Ruither O. G. Carolino
Publikováno v:
Journal of biochemical and molecular toxicology. 31(10)
Arthropod venoms are sources of molecules that may be useful tools to investigate molecular mechanisms of putative new medicines and laboratory drugs. Here we show the effects of the compound agelaiatoxin-8 (AVTx8), isolated from Agelaia vicina venom
Autor:
Rene Oliveira Beleboni, Wagner Ferreira dos Santos, Leonardo Gobbo-Neto, Joaquim Coutinho-Netto, Renato Guizzo, Andrea Baldocchi Pizzo, Ruither O. G. Carolino, Norberto Peporine Lopes, Andréia Cristina Karklin Fontana
Publikováno v:
Molecular Pharmacology. 69:1998-2006
The major contribution of this work is the isolation of a neuroprotective compound referred to as 2-amino-5-ureidopentanamide (FrPbAII) (M(r) = 174) from Parawixia bistriata spider venom and an investigation of its mode of action. FrPbAII inhibits sy
Autor:
Ruither O. G. Carolino, N. Garcia-Cairasco, Joaquim Coutinho-Netto, Andrea Baldocchi Pizzo, Flávio Del Vecchio, Miguel Moyses-Neto, Wagner Ferreira dos Santos, Rene Oliveira Beleboni
Publikováno v:
Neurochemistry International. 46:523-531
We obtained a neurotoxic fraction (AcTx) from star fruit (Averrhoa carambola) and studied its effects on GABAergic and glutamatergic transmission systems. AcTx had no effect on GABA/glutamate uptake or release, or on glutamate binding. However, it sp
Autor:
Wagner Ferreira dos Santos, Antonio Miranda, Márcia Renata Mortari, Alexandra Olimpio Siqueira Cunha, Luciana R. de Oliveira, Andrea Baldocchi Pizzo, Norberto Cysne Coimbra
Publikováno v:
Brain Research. 1031:74-81
Several investigations have provided information that defensive behaviors evoked by stimulation of deep layers of the superior colliculus (dlSC) are subjected to inhibitory nigral modulation. This inhibition is made mainly through GABAergic neurons f
Autor:
Joaquim Coutinho-Netto, Alessandra Mussi Ribeiro, Wagner Ferreira dos Santos, Andrea Baldocchi Pizzo, Rene Oliveira Beleboni, Antonio Miranda, Andréia Cristina Karklin Fontana
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 18:61-68
It has previously been shown that the denatured crude extract of Agelaia vicina wasp venom inhibits glutamate and GABA uptake in rat cerebral cortex synaptosomes. To identify the components responsible for these effects, the neurotoxin AvTx 7 (molecu
Autor:
Alessandra Mussi Ribeiro, Wagner Ferreira dos Santos, Rene Oliveira Beleboni, Andréia Cristina Karklin Fontana, M.A.R. Cairrão, Antonio Miranda, Andrea Baldocchi Pizzo, Joaquim Coutinho-Netto
Publikováno v:
Pharmaceutical Biology. 40:472-477
In this article we describe an in vivo anticonvulsant effect from denatured crude venom and partially isolated fractions from two spiders: Parawixia bistriata and Scaptocosa raptoria. Intracerebroventricular injections of these venoms and fractions a
Autor:
Joaquim Coutinho-Netto, Wagner Ferreira dos Santos, Andrea Baldocchi Pizzo, Andréia Cristina Karklin Fontana
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 14:88-94
Glutamate (L-glu) is the most important excitatory neurotransmitter in the mammalian central nervous system. Its action is terminated by transporters located in the plasma membrane of neurons and glial cells, which have a critical role in preventing
Autor:
Rene Oliveira Beleboni, Andrea Baldocchi Pizzo, Ruither O. G. Carolino, Norberto Cysne Coimbra, Lissandra Castellan-Baldan, Joaquim Coutinho-Netto, Wagner Ferreira dos Santos
Publikováno v:
Cellular and molecular neurobiology. 24(6)
1. The GABAergic neurotransmission has been implicated in the modulation of many neural networks in forebrain, midbrain and hindbrain, as well as, in several neurological disorders. 2. The complete comprehension of GABA system neurochemical propertie
Autor:
Rene Oliveira Beleboni, Ruither O. G. Carolino, Wagner Ferreira dos Santos, Andrea Baldocchi Pizzo, Joaquim Coutinho-Netto, Andréia Cristina Karklin Fontana
Publikováno v:
European journal of pharmacology. 493(1-3)
Venoms from several arthropods are recognized as useful sources of bioactive substances, such as peptides, acylpolyamines, and alkaloids, which show a wide range of pharmacological effects on synaptic transmission. In this work, we summarize and comp
Autor:
Renê Oliveira Beleboni, Ruither Oliveira Gomes Carolino, Andrea Baldocchi Pizzo, Lissandra Castellan-Baldan, Joaquim Coutinho-Netto, Wagner Ferreira dos Santos, Norberto Cysne Coimbra
Publikováno v:
Cellular & Molecular Neurobiology; Dec2004, Vol. 24 Issue 6, p707-728, 22p