Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Andrea Arricibita Varea"'
Autor:
Sophie Ottema, Roger Mulet-Lazaro, Claudia Erpelinck-Verschueren, Stanley van Herk, Marije Havermans, Andrea Arricibita Varea, Michael Vermeulen, H. Berna Beverloo, Stefan Gröschel, Torsten Haferlach, Claudia Haferlach, Bas J. Wouters, Eric Bindels, Leonie Smeenk, Ruud Delwel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Chromosome rearrangements can be a cause of altered oncogene expression in cancer, such as a 3q26 translocation in some acute myeloid leukemias (AML) that leads to overexpression of EVI1. Here the authors engineer this rearrangement in a cell line an
Externí odkaz:
https://doaj.org/article/7df6196de175464e8b50bb614eba9c97
Autor:
H. Berna Beverloo, Ruud Delwel, Eric Bindels, Marije Havermans, Sophie Ottema, Stefan Gröschel, Michael Vermeulen, Bas J. Wouters, Torsten Haferlach, Leonie Smeenk, Claudia A.J. Erpelinck-Verschueren, Claudia Haferlach, Roger Mulet-Lazaro, Andrea Arricibita Varea, Stanley van Herk
Publikováno v:
Nature Communications, 12(1):5679. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Chromosomal rearrangements are a frequent cause of oncogene deregulation in human malignancies. Overexpression of EVI1 is found in a subgroup of acute myeloid leukemia (AML) with 3q26 chromosomal rearrangements, which is often therapy resistant. In A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39af26ea606ee42cf0d14c739198eca
https://pure.eur.nl/en/publications/04f21b77-cbaa-43f7-a02e-7d978a9554bd
https://pure.eur.nl/en/publications/04f21b77-cbaa-43f7-a02e-7d978a9554bd
Autor:
Erik van Dijk, Jan Paul Medema, Bauke Ylstra, Daniël M. Miedema, Kristiaan J. Lenos, Veronique L. Veenstra, Lisanne E. Nijman, Maartje van der Heijden, Sanne M. van Neerven, Nina E. de Groot, Martin A. Nowak, Douglas J. Winton, Andrea Arricibita Varea, Bartlomiej Waclaw, Edward Morrissey, Maarten F. Bijlsma, Maria C. Lecca, Pramudita R. Prasetyanti, Sophie C. Lodestijn, Louis Vermeulen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 116(13), 6140-6145. National Academy of Sciences
van der Heijden, M, Miedema, D, Waclaw, B, Veenstra, V, Lecca, M, Nijman, L, Dijk, E, van Neerven, S, Lodestijn, S, Lenos, K, de Groot, N, Prasetyanti, P, Arricibita Varea, A, Winton, D, Medema, J P, Morrissey, E, Ylstra, B, Nowak, M, Bijlsma, M & Vermeulen, L 2019, ' Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts ', Proceedings of the National Academy of Sciences, vol. 116, no. 13, pp. 6140-6145 . https://doi.org/10.1073/pnas.1813417116
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
van der Heijden, M, Miedema, D M, Waclaw, B, Veenstra, V L, Lecca, M C, Nijman, L E, van Dijk, E, van Neerven, S M, Lodestijn, S C, Lenos, K J, de Groot, N E, Prasetyanti, P R, Varea, A A, Winton, D J, Medema, J P, Morrissey, E, Ylstra, B, Nowak, M A, Bijlsma, M F & Vermeulen, L 2019, ' Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts ', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 13, pp. 6140-6145 . https://doi.org/10.1073/pnas.1813417116
van der Heijden, M, Miedema, D, Waclaw, B, Veenstra, V, Lecca, M, Nijman, L, Dijk, E, van Neerven, S, Lodestijn, S, Lenos, K, de Groot, N, Prasetyanti, P, Arricibita Varea, A, Winton, D, Medema, J P, Morrissey, E, Ylstra, B, Nowak, M, Bijlsma, M & Vermeulen, L 2019, ' Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts ', Proceedings of the National Academy of Sciences, vol. 116, no. 13, pp. 6140-6145 . https://doi.org/10.1073/pnas.1813417116
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
van der Heijden, M, Miedema, D M, Waclaw, B, Veenstra, V L, Lecca, M C, Nijman, L E, van Dijk, E, van Neerven, S M, Lodestijn, S C, Lenos, K J, de Groot, N E, Prasetyanti, P R, Varea, A A, Winton, D J, Medema, J P, Morrissey, E, Ylstra, B, Nowak, M A, Bijlsma, M F & Vermeulen, L 2019, ' Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts ', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 13, pp. 6140-6145 . https://doi.org/10.1073/pnas.1813417116
Significance Colorectal cancer (CRC) is a heterogeneous disease, with significant variation in genotype and phenotype within each individual tumor. This intratumor heterogeneity emerges during tumor development due to clonal evolution and in part can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3067c66ea779680d543b2321a5015fc
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85063961772&origin=inward
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85063961772&origin=inward