Výsledky vyhledávání - "Andrea Ardid-Ruiz"

Akademický článek

A novel dietary multifunctional ingredient reduces body weight and improves leptin sensitivity in cafeteria diet-fed rats

Autor: Miguel Z. Martín-González, Héctor Palacios-Jordan, Maria Ibars, Andrea Ardid-Ruiz, Albert Gibert-Ramos, Miguel A. Rodríguez, Manuel Suárez, Begoña Muguerza, Gerard Aragonès

Publikováno v: Journal of Functional Foods, Vol 73, Iss , Pp 104141- (2020)

The use of a single family of dietary bioactive compounds has not been sufficient to manage highly regulated mechanisms such as body weight. Therefore, we aimed to evaluate the effect of a multifunctional ingredient (MIX) based on the co-administrati

Externí odkaz: https://doaj.org/article/25d41668571e462a862d289f3859e84e

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The effects of Vitis vinifera L. phenolic compounds on a blood-brain barrier culture model: Expression of leptin receptors and protection against cytokine-induced damage

Autor: Cinta Bladé, Andrea Ardid-Ruiz, András Harazin, Lilla Barna, Mária A. Deli, Gerard Aragonès, Manuel Suárez, Fruzsina R. Walter

Publikováno v: Journal of ethnopharmacology. 247

Ethnopharmacological relevance The medicinal properties of grapes (Vitis vinifera L.) are well known since ancient times. Ethnobotanical grape preparations, like the Ayurvedic Darakchasava are used as cardiotonic and for the treatment of cardiovascul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389b03185659ccd9421a743453bc0f49
https://pubmed.ncbi.nlm.nih.gov/31562952

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Potential Involvement of Peripheral Leptin/STAT3 Signaling in the Effects of Resveratrol and Its Metabolites on Reducing Body Fat Accumulation

Autor: Gerard Aragonès, Maria Ibars, Manuel Suárez, Daniele Del Rio, Pedro Mena, Andrea Ardid-Ruiz, Lluís Arola, Cinta Bladé, Begoña Muguerza

Publikováno v: Nutrients
Volume 10
Issue 11
Nutrients, Vol 10, Iss 11, p 1757 (2018)

Bioactive compounds such as polyphenols have increased in importance in recent years, and among them, resveratrol (3,5,4&prime
trihydroxy-trans-stilbene) has generated great interest as an anti-obesity agent. Recent investigations have highlight

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85f78f8d03d12ca4454e29223a389ba

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Seasonal consumption of polyphenol-rich fruits affects the hypothalamic leptin signaling system in a photoperiod-dependent mode

Autor: Albert Gibert-Ramos, Gerard Aragonès, Andrea Ardid-Ruiz, Maria Ibars, Cinta Bladé, Manuel Suárez, Anna Arola-Arnal

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)

Leptin has a central role in the maintenance of energy homeostasis, and its sensitivity is influenced by both the photoperiod and dietary polyphenols. The aim of this study was to investigate the effect of seasonal consumption of polyphenol-rich frui

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a2c4625153435eb3acb5f9ae4ca1f4
https://doi.org/10.1038/s41598-018-31855-y

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Resveratrol Treatment Enhances the Cellular Response to Leptin by Increasing OBRb Content in Palmitate-Induced Steatotic HepG2 Cells

Autor: Manuel Suárez, Daniele Del Rio, Lluís Arola, Begoña Muguerza, Gerard Aragonès, Maria Ibars, Pedro Mena, Andrea Ardid-Ruiz

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 24

The interaction of leptin with its hepatic longest receptor (OBRb) promotes thephosphorylation of signal transducer and activator of transcription‐3 (STAT3), protecting the liverfrom lipid accumulation. However, leptin signalling is disrupted in he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aaef1315cb7cfab7bbdffbc555f91b6
https://doi.org/10.3390/ijms20246282

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Combined Ligand- and Receptor-Based Virtual Screening Methodology to Identify Structurally Diverse Protein Tyrosine Phosphatase 1B Inhibitors

Autor: Gerard Pujadas, Gerard Aragonès, Cristina Valls, Adrià Cereto-Massagué, Manuel Suárez, Raúl Beltrán-Debón, Andrea Ardid-Ruiz, María José Ojeda-Montes, Santiago Garcia-Vallvé, Miquel Mulero, Aleix Gimeno, Sarah Tomás-Hernández

Publikováno v: ChemMedChem. 13(18)

Protein tyrosine phosphatase 1B (PTP1B) is a potential drug target for diabetes and obesity. However, the design of PTP1B inhibitors that combine potency and bioavailability is a great challenge, and new leads are needed to circumvent this problem. V

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0322f6009c01a98180fef25483126fd7
https://pubmed.ncbi.nlm.nih.gov/30024103

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Ephedrine as a lead compound for the development of new DPP-IV inhibitors

Autor: Gerard Pujadas, Cristina Valls, María José Ojeda-Montes, Andrea Ardid-Ruiz, Aleix Gimeno, Adrià Cereto-Massagué, Sarah Tomás-Hernández, Miquel Mulero, Raúl Beltrán-Debón, Santiago Garcia-Vallvé

Publikováno v: Future medicinal chemistry. 9(18)

Aim: Extracts from Ephedra species have been reported to be effective as antidiabetics. A previous in silico study predicted that ephedrine and five ephedrine derivatives could contribute to the described antidiabetic effect of Ephedra extracts by in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d04d15eecb05b3b85783b773c36fbf9
https://pubmed.ncbi.nlm.nih.gov/29172693

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Modulation of leptin resistance by food compounds

Autor: Andrea Ardid-Ruiz, Cinta Bladé, Gerard Aragonès, Maria Ibars, Manuel Suárez

Publikováno v: Molecular Nutrition & Food Research

DOI: 10.1002/mnfr.201500964 URL: http://onlinelibrary.wiley.com/doi/10.1002/mnfr.201500964/abstract Filiació URV: SI Review Leptin is mainly secreted by white adipose tissue and regulates energy homeostasis by inhibiting food intake and stimulating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce18cf9f62c01e5c660e2055c6c80d6e
http://hdl.handle.net/20.500.11797/PC1945

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Dietary proanthocyanidins boost hepatic NAD + metabolism and SIRT1 expression and activity in a dose-dependent manner in healthy rats

Autor: Manuel Suárez, Maria Vinaixa, Gerard Aragonès, Cinta Bladé, Miguel A. Rodríguez, Lluís Arola, Xavier Correig, Andrea Ardid-Ruiz

Publikováno v: Scientific Reports

Proanthocyanidins (PACs) have been reported to modulate multiple targets by simultaneously controlling many pivotal metabolic pathways in the liver. However, the precise mechanism of PAC action on the regulation of the genes that control hepatic meta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d439d0e4dfb19be0c10b26abef2476
http://hdl.handle.net/20.500.11797/PC1484

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Dietary proanthocyanidins boost hepatic NAD + metabolism and SIRT1 expression and activity in a dose-dependent manner in healthy rats

Autor: Gerard Aragonès, Manuel Suárez, Andrea Ardid-Ruiz, Maria Vinaixa, Miguel A. Rodríguez, Xavier Correig, Lluís Arola, Cinta Bladé

Publikováno v: Scientific Reports
Repositori Institucional de la Universitat Rovira i Virgili
Universitat Rovira i virgili (URV)

DOI: 10.1038/srep24977 Proanthocyanidins (PACs) have been reported to modulate multiple targets by simultaneously controlling many pivotal metabolic pathways in the liver. However, the precise mechanism of PAC action on the regulation of the genes th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::1a82b9ed7747e169debfee1865de699b
http://hdl.handle.net/20.500.11797/PC1484

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