Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andrea Štefaniková"'
Autor:
Katarina Dibdiakova, Eva Vidomanová, Ivana Pilchova, Jozef Hatok, Lucia Lichardusova, Peter Racay, Katarina Klacanova, Simona Saksonova, Andrea Štefaniková
Publikováno v:
Neurochemical Research. 42:3170-3185
Overload or dysfunction of ubiquitin-proteasome system (UPS) is implicated in mechanisms of neurodegeneration associated with neurodegenerative diseases, e.g. Parkinson and Alzheimer disease, and ischemia-reperfusion injury. The aim of this study was
Publikováno v:
General physiology and biophysics. 36:539-547
Colorectal carcinoma (CRC) that represents one of the major causes for cancer-related death in humans is often associated with over-expression of anti-apoptotic proteins of Bcl-2 family. The aim of presented study was to determine the effect of ABT-7
Autor:
Peter Racay, Dusan Dobrota, Ivana Pilchova, Jozef Hatok, Katarína Kliková, Andrea Štefaniková
Publikováno v:
Klinicka onkologie. 29:29-38
Heat shock proteins (HSPs) HSP27, HSP70 and HSP90 are molecular chaperones; their expression is increased after exposure of cells to conditions of environmental stress, including heat shock, heavy metals, oxidative stress, or pathologic conditions, s
Autor:
Ivana Pilchova, Peter Racay, Dusan Dobrota, Peter Chudý, Katarína Kliková, Andrea Štefaniková, Juraj Chudej, Jozef Hatok
Publikováno v:
General physiology and biophysics. 34:33-42
Bortezomib (PS-341, or Velcade), reversible inhibitor of 20S proteasome approved for the treatment of multiple myeloma and mantle cell lymphoma, exhibited a cytotoxic effect toward other malignancies including leukaemia. In this study, we have docume
Publikováno v:
General physiology and biophysics. 32:505-516
The aim of presented study was to determine effect of NaBu in combination with ABT-737 on cell survival of leukemic cell line HL-60. In addition, analysis of molecular mechanism of NaBu action with a focus on mitochondrial apoptosis was performed. Bo
Autor:
Peter Racay, Jana Jurečeková, Katarína Kliková, Andrea Štefaniková, Jozef Hatok, Dusan Dobrota
Publikováno v:
Acta Medica Martiniana, Vol 11, Iss 3, Pp 15-23 (2011)
Bcl-2 Family Proteins in Development and Treatment of Malignant DiseasesProteins of Bcl-2 family are key regulators of mitochondrial pathway of apoptosis. Deregulation of apoptosis disrupts the complex and delicate balance between cell proliferation,
Publikováno v:
General physiology and biophysics. 30:3-12
Many studies suggest that killing of tumour cell by commonly used therapies (chemotherapy, radiotherapy) is mediated primarily by induction of apoptosis. Therefore, resistance of tumour cells to therapy can be caused by a failure in the ability to in
Autor:
Alexandra Gondova, Andrea Štefaniková, Pavol Zubor, Karol Kajo, Jozef Hatok, Jan Danko, Zuzana Dankova, Peter Kubatka, Igor Stastny, Michal Kalman
Publikováno v:
The Breast. 32:S50