Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Andrea, Steinborn"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionImmunosuppressive therapy prevents graft rejection but increases the risk of non-melanoma skin cancer (NMSC), especially in elderly kidney transplant recipients (KTR).MethodsIn this study, we separately investigated the differentiation of
Externí odkaz:
https://doaj.org/article/7940558942c54ed88cff01d8a0d66b13
Autor:
Jonas Leonhard, Matthias Schaier, Florian Kälble, Volker Eckstein, Martin Zeier, Andrea Steinborn
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic kidney failure (KF) provokes the development of immune senescent CD8+ cytotoxic T cells, affecting the occurrence of graft rejection, viral infections, and malignancies after kidney transplantation. In this study, we analyzed the impact of KF
Externí odkaz:
https://doaj.org/article/bb5e1071a98c43aebc4678581c0e77d7
Autor:
Matthias Schaier, Claudius Gottschalk, Lorenz Uhlmann, Claudius Speer, Florian Kälble, Volker Eckstein, Carsten Müller-Tidow, Stefan Meuer, Karsten Mahnke, Hanns-Martin Lorenz, Martin Zeier, Andrea Steinborn
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-17 (2018)
Abstract Background CD4+ T cells are of great importance in the pathogenesis of systemic lupus erythematosus (SLE), as an imbalance between CD4+ regulatory T cells (Tregs) and CD4+ responder T cells (Tresps) causes flares of active disease in SLE pat
Externí odkaz:
https://doaj.org/article/ac2b83be5c3b4ba180c6c858fbe4955c
Autor:
Matthias, Schaier, Claudius, Gottschalk, Florian, Kälble, Lorenz, Uhlmann, Volker, Eckstein, Carsten, Müller-Tidow, Stefan, Meuer, Karsten, Mahnke, Hanns-Martin, Lorenz, Martin, Zeier, Andrea, Steinborn
Publikováno v:
Clinical and Experimental Rheumatology. 39:279-288
An imbalance between CD4+-regulatory T-cells (Tregs) and CD4+-responder T-cells (Tresps) correlates with active disease flares in systemic lupus erythematosus (SLE) patients. Both cell subsets consist of highly proliferating Tregs/Tresps expressing i
Autor:
Jonas, Leonhard, Matthias, Schaier, Florian, Kälble, Volker, Eckstein, Martin, Zeier, Andrea, Steinborn
Publikováno v:
Frontiers in immunology. 13
Chronic kidney failure (KF) provokes the development of immune senescent CD8
Autor:
Florian, Kälble, Lisa, Wu, Hanns-Martin, Lorenz, Martin, Zeier, Matthias, Schaier, Andrea, Steinborn
Publikováno v:
International Journal of Molecular Sciences
Dysregulations in the differentiation of CD4+-regulatory-T-cells (Tregs) and CD4+-responder-T-cells (Tresps) are involved in the development of active systemic lupus erythematosus (SLE). Three differentiation pathways of highly proliferative inducibl
Autor:
Martin Zeier, Florian Kälble, Claudius Speer, Hanns-Martin Lorenz, Andrea Steinborn, Claudia Sommerer, Daniela Kim, Alexander Kunz, Michael Schmitt, Anita Schmitt, Matthias Schaier, Christian Morath, Lei Wang, Christian Kleist, Christian Nusshag
Publikováno v:
Oral Presentations.
Background: Modified immune cells (MICs) are mononuclear cells that gain immunosuppressive properties after incubation with the proliferation inhibitor mitomycin C. We recently showed that syngeneic MIC therapy controlled experimental autoimmune ence
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims An imbalance between CD4+-regulatory T-cells (Tregs) and CD4+-responder T-cells (Tresps) correlates with active disease flares in Systemic Lupus Erythematosus (SLE) patients. Both cell subsets consist of highly proliferative induc
Autor:
Matthias Schaier, Nicole Seissler, Edgar Schmitt, Stefan Meuer, Friederike Hug, Martin Zeier, Andrea Steinborn
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34208 (2012)
Recent studies show that regulatory T cells (Tregs) play an essential role in tolerance induction after organ transplantation. In order to examine whether there are differences in the composition of the total CD4(+)CD127(low+/-)FoxP3(+)- Treg cell po
Externí odkaz:
https://doaj.org/article/a9c589855b5d4e26a2dac434fe9ddfed
Autor:
Andrea Steinborn, Martin Zeier, Florian Kälble, Karsten Mahnke, Stefan Meuer, Christian Morath, Volker Eckstein, Lorenz Uhlmann, Matthias Schaier, Anthony D. Ho, Claudia Sommerer, Carsten Mueller-Tidow, Angele Leick
Publikováno v:
Immunology. 155:211-224
Premature aging of both CD4+ regulatory T (Treg) and CD4+ responder‐T (Tresp) cells in patients with end‐stage renal disease (ESRD) is expected to affect the success of later kidney transplantation. Both T‐cell populations are released from the