Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Andrea, Shen"'
Autor:
Pramod P. Mehta, Tod Smeal, Min-Jean Yin, Gerrit Los, Michael R. Gehring, Shinji Yamazaki, Marlena Walls, Leslie Nguyen, Andrea Shen, Pei-Pei Kung
Publikováno v:
Cancer Letters. 300:30-39
Hsp90 is required for conformational maturation and stability of numerous key signaling proteins (clients) involved in cell proliferation and transformation. Here we describe two novel Hsp90 inhibitors, PF-4470296 and PF-3823863, demonstrate a differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d810a11ef9391e869058312d76a54b8
https://doi.org/10.1016/j.canlet.2010.09.002
https://doi.org/10.1016/j.canlet.2010.09.002
Autor:
Pramod P, Mehta, Pei-Pei, Kung, Shinji, Yamazaki, Marlena, Walls, Andrea, Shen, Leslie, Nguyen, Michael R, Gehring, Gerrit, Los, Tod, Smeal, Min-Jean, Yin
Publikováno v:
Cancer Letters. 422:132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae583f9598d4454e906d62d8c3b6ca7
https://doi.org/10.1016/j.canlet.2018.03.019
https://doi.org/10.1016/j.canlet.2018.03.019
Autor:
Jon Engebretse, Pamela Jo Berlinski, Jeffrey H. Chen, Shaoxian Sun, Eric Zhang, Bernadette Pascual, John Barker, Nancy Forester, Aileen McHarg, Leslie Nguyen, Michael R. Gehring, Aihua Zou, Henry Cheng, Steven Glenn Kamerling, Heather Colhoun, Shubha Bagrodia, Tom Carlson, Michelle Hemkens, Keith R. Marotti, Kristina Rafidi, Chau Almaden, Jing Yuan, Sophie Wang, Andrea Shen, William Carley
Publikováno v:
Cancer Research. 70:5043-5043
PF-04691503 is a dual inhibitor of both PI3K and mTOR, inhibits PI3K signaling in cancer cell lines, and exhibits in vitro and in vivo anti-proliferative activity in PI3K-pathway driven cell lines. It is a nanomolar inhibitor of all 4 isoforms of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c13d86cef4a730ca8aebab3638ff526
https://doi.org/10.1158/1538-7445.am10-5043
https://doi.org/10.1158/1538-7445.am10-5043