Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Andrea, Mafficini"'
Autor:
Emilia Alors‐Pérez, Ricardo Blázquez‐Encinas, María Trinidad Moreno‐Montilla, Víctor García‐Vioque, Juan Manuel Jiménez‐Vacas, Andrea Mafficini, Iranzu González‐Borja, Claudio Luchini, Juan M. Sánchez‐Hidalgo, Marina E. Sánchez‐Frías, Sergio Pedraza‐Arevalo, Antonio Romero‐Ruiz, Rita T. Lawlor, Antonio Viúdez, Manuel D. Gahete, Aldo Scarpa, Álvaro Arjona‐Sánchez, Raúl M. Luque, Alejandro Ibáñez‐Costa, Justo P. Castaño
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2524-2540 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, characterized by late diagnosis and poor treatment response. Surgery is the only curative approach, only available to early‐diagnosed patients. Current therapies have limited effect
Externí odkaz:
https://doaj.org/article/de947d6fca6d49f9911a2528b10949ca
Autor:
Michele Rota, Federico Sganzerla, Michele Zuffante, Andrea Mafficini, Michele Pavarana, Michele Milella
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Gastrointestinal stromal tumors (GISTs) are the most frequent mesenchymal tumors of the gastrointestinal tract, usually arising in the stomach or in the small bowel. Most GISTs are diagnosed early due to the presence of symptoms (e.g., abdominal disc
Externí odkaz:
https://doaj.org/article/b108cd57014f46898c0cd2d745f4ac65
Autor:
Federica Danzi, Raffaella Pacchiana, Andrea Mafficini, Maria T. Scupoli, Aldo Scarpa, Massimo Donadelli, Alessandra Fiore
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-22 (2023)
Abstract Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed activities include a complete rewiring of the bioenerget
Externí odkaz:
https://doaj.org/article/d69fa386a75843c9b780e593ba2a93a5
Autor:
Emilia Alors-Perez, Ricardo Blázquez-Encinas, Sonia Alcalá, Cristina Viyuela-García, Sergio Pedraza-Arevalo, Vicente Herrero-Aguayo, Juan M. Jiménez-Vacas, Andrea Mafficini, Marina E. Sánchez-Frías, María T. Cano, Fernando Abollo-Jiménez, Juan A. Marín-Sanz, Pablo Cabezas-Sainz, Rita T. Lawlor, Claudio Luchini, Laura Sánchez, Juan M. Sánchez-Hidalgo, Sebastián Ventura, Laura Martin-Hijano, Manuel D. Gahete, Aldo Scarpa, Álvaro Arjona-Sánchez, Alejandro Ibáñez-Costa, Bruno Sainz, Raúl M. Luque, Justo P. Castaño
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-21 (2021)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, requiring novel treatments to target both cancer cells and cancer stem cells (CSCs). Altered splicing is emerging as both a novel cancer hallmark and an attractive
Externí odkaz:
https://doaj.org/article/2e57a0d7fd7f42d6a9f88e1c0cae6aca
Autor:
Valeria Barresi, Michele Simbolo, Andrea Mafficini, Maurizio Martini, Martina Calicchia, Maria Liliana Piredda, Chiara Ciaparrone, Giada Bonizzato, Serena Ammendola, Maria Caffo, Giampietro Pinna, Francesco Sala, Rita Teresa Lawlor, Claudio Ghimenton, Aldo Scarpa
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Giant cell glioblastoma (GC-GBM) is a rare variant of IDH-wt GBM histologically characterized by the presence of numerous multinucleated giant cells and molecularly considered a hybrid between IDH-wt and IDH-mutant GBM. The lack of an object
Externí odkaz:
https://doaj.org/article/99e7b82f197643438e67e5c88a14ad33
Autor:
Corrado Pedrazzani, Cristian Conti, Angelo Di Vittori, Giulia Turri, Laura Bernardoni, Andrea Mafficini, Claudio Luchini, Armando Gabbrielli, Aldo Scarpa, Alfredo Guglielmi
Publikováno v:
Asian Journal of Surgery, Vol 46, Iss 2, Pp 924-925 (2023)
Externí odkaz:
https://doaj.org/article/6a30ca8a9dd5413cb64c60dbbd19e910
Autor:
Vanessa Lakis, Rita T. Lawlor, Felicity Newell, Ann-Marie Patch, Andrea Mafficini, Anguraj Sadanandam, Lambros T. Koufariotis, Rebecca L. Johnston, Conrad Leonard, Scott Wood, Borislav Rusev, Vincenzo Corbo, Claudio Luchini, Sara Cingarlini, Luca Landoni, Roberto Salvia, Michele Milella, David Chang, Peter Bailey, Nigel B. Jamieson, Fraser Duthie, Marie-Claude Gingras, Donna M. Muzny, David A. Wheeler, Richard A. Gibbs, Massimo Milione, APGI, ARC-Net, Paolo Pederzoli, Jaswinder S. Samra, Anthony J. Gill, Amber L. Johns, John V. Pearson, Andrew V. Biankin, Sean M. Grimmond, Nicola Waddell, Katia Nones, Aldo Scarpa
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Lakis et al. report novel findings related to the epigenetic landscape of pancreatic neuroendocrine cancer. This relatively large cohort provides functional insights into the epigenetic wiring of pancreatic neuroendocrine tumor sub-types with the pot
Externí odkaz:
https://doaj.org/article/a00f8e4047594060951453f3f2ee9216
Autor:
Cecily P. Vaughn, José Luis Costa, Harriet E. Feilotter, Rosella Petraroli, Varun Bagai, Anna Maria Rachiglio, Federica Zito Marino, Bastiaan Tops, Henriette M. Kurth, Kazuko Sakai, Andrea Mafficini, Roy R. L. Bastien, Anne Reiman, Delphine Le Corre, Alexander Boag, Susan Crocker, Michel Bihl, Astrid Hirschmann, Aldo Scarpa, José Carlos Machado, Hélène Blons, Orla Sheils, Kelli Bramlett, Marjolijn J. L. Ligtenberg, Ian A. Cree, Nicola Normanno, Kazuto Nishio, Pierre Laurent-Puig
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Gene fusion events resulting from chromosomal rearrangements play an important role in initiation of lung adenocarcinoma. The recent association of four oncogenic driver genes, ALK, ROS1, RET, and NTRK1, as lung tumor predictive b
Externí odkaz:
https://doaj.org/article/b32c4dd2b6ba4fa0b53d8d7901cbaab5
Autor:
Michele Simbolo, Caterina Vicentini, Andrea Ruzzenente, Matteo Brunelli, Simone Conci, Matteo Fassan, Andrea Mafficini, Borislav Rusev, Vincenzo Corbo, Paola Capelli, Emilio Bria, Serena Pedron, Giona Turri, Rita T. Lawlor, Giampaolo Tortora, Claudio Bassi, Alfredo Guglielmi, Aldo Scarpa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract The incidence and mortality rates of intrahepatic cholangiocarcinoma have been rising worldwide. Few patients present an early-stage disease that is amenable to curative surgery and after resection, high recurrence rates persist. To identify
Externí odkaz:
https://doaj.org/article/43514a3462ab48c3877101c0b0918453
Autor:
Jun Wang, Laurent Dumartin, Andrea Mafficini, Pinar Ulug, Ajanthah Sangaralingam, Namaa Audi Alamiry, Tomasz P. Radon, Roberto Salvia, Rita T. Lawlor, Nicholas R. Lemoine, Aldo Scarpa, Claude Chelala, Tatjana Crnogorac-Jurcevic
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Despite a wealth of genomic information, a comprehensive alternative splicing (AS) analysis of pancreatic ductal adenocarcinoma (PDAC) has not been performed yet. In the present study, we assessed whole exome-based transcriptome and AS profi
Externí odkaz:
https://doaj.org/article/5e296d11dc7c438894ef3382cb3a4a71