Výsledky vyhledávání - "Andrea, Gil Lorenzo"

Akademický článek

Physiological Functions and Regulation of the Na+/H+ Exchanger [NHE1] in Renal Tubule Epithelial Cells

Autor: Patricia G Vallés, Victoria Bocanegra, Andrea Gil Lorenzo, Valeria Victoria Costantino

Publikováno v: Kidney & Blood Pressure Research, Vol 40, Iss 5, Pp 452-466 (2015)

The sodium-hydrogen exchanger isoform-1 [NHE1] is a ubiquitously expressed plasma membrane protein that plays a central role in intracellular pH and cell volume homeostasis by catalyzing an electroneutral exchange of extracellular sodium and intracel

Externí odkaz: https://doaj.org/article/122ea3ce0517439b95e376d68514509c

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Hsp70 regulation on Nox4/p22phox and cytoskeletal integrity as an effect of losartan in vascular smooth muscle cells

Autor: Victoria Bocanegra, Patricia G. Vallés, Andrea Gil Lorenzo, María Eugenia Benardon, Valeria Cacciamani

Publikováno v: Cell Stress and Chaperones. 19:115-134

A series of signaling cascades are activated after angiotensin II binds to angiotensin II type I receptor (AT1R), a peptide that is an important mediator of oxidative stress. Hsp70 regulates a diverse set of signaling pathways through interactions wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043c6aa1697f00777236e82bf33423b9
https://doi.org/10.1007/s12192-013-0439-6

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RhoA and MAPK signal transduction pathways regulate NHE1-dependent proximal tubule cell apoptosis after mechanical stretch

Autor: Valeria Costantino, Patricia G. Vallés, Valeria Cacciamani, Victoria Bocanegra, Andrea Gil Lorenzo, María Eugenia Benardon

Publikováno v: American journal of physiology. Renal physiology. 307(7)

Mechanical deformation after congenital ureteral obstruction is traduced into biochemical signals leading to tubular atrophy due to epithelial cell apoptosis. We investigated whether Na+/H+exchanger 1 (NHE1) could be responsible for HK-2 cell apoptos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfe250fae4991ace93538d62ecc1cac
https://pubmed.ncbi.nlm.nih.gov/25080524

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Acute kidney injury: what part do toll-like receptors play?

Autor: Andrea Gil Lorenzo, Patricia G. Vallés, Victoria Bocanegra, Roberto Vallés

Publikováno v: International Journal of Nephrology and Renovascular Disease
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The innate immune system plays an important role as a first response to tissue injury. This first response is carried out via germline-encoded receptors. Toll-like receptors (TLRs) are the first identified and best studied family of pattern recogniti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9fcd09db4ffef46df3e48e23fcba0f
https://pubmed.ncbi.nlm.nih.gov/24971030

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Angiotensin AT(1) receptor inhibition-induced apoptosis by RhoA GTPase activation and pERK1/2 signaling pathways in neonatal obstructive nephropathy

Autor: Victoria, Bocanegra, Martin, Rinaldi Tosi, Andrea, Gil Lorenzo, Valeria, Cacciamani, Walter, Manucha, Miguel, Fornés, Patricia G, Vallés

Publikováno v: Histology and histopathology. 27(7)

Intrarenal renin-Angiotensin system (RAS) activity is increased during early development and is further enhanced by unilateral ureteral obstruction (UUO). We studied the involvement of mitogen-activated protein (MAP) kinase members and the RhoA GTPas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::939f2a9e2c5f15c75ccd790fd2dbd0cf
https://pubmed.ncbi.nlm.nih.gov/22648547

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The Nrf2-Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO)

Autor: Walter Manucha, Andrea Gil Lorenzo, Martin Rinaldi Tosi, Victoria Bocanegra, Patricia G. Vallés

Publikováno v: Cell stresschaperones. 16(1)

Perturbation of renal tubular antioxidants and overproduction of reactive oxygen species may amplify the proinflammatory state of renal obstruction, culminating in oxidative stress and tubular loss. Here, we analyzed the heat shock protein 70 (Hsp70)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e673ecaeb021e6e7348e011fbab2d4a5
https://pubmed.ncbi.nlm.nih.gov/20734248

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Garlic components inhibit angiotensin II-induced cell-cycle progression and migration: Involvement of cell-cycle inhibitor p27(Kip1) and mitogen-activated protein kinase

Autor: Andrea Gil Lorenzo, Claudia Castro, Adriana Gonzalez, Montserrat Cruzado

Publikováno v: Molecular nutritionfood research. 54(6)

Garlic has been used for prevention and treatment of hypertension; however, the molecular mechanisms of garlic's effects remain to be elucidated. In this study, the mechanisms of the in vitro effect of organosulphur compounds derived from garlic on g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd1093e6b579ddb09047c5cf42f51ff
https://pubmed.ncbi.nlm.nih.gov/19904760

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