Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Andrea, Ferrigno"'
Autor:
Laura Giuseppina Di Pasqua, Murwan Mahmoud Abdallah, Fausto Feletti, Mariapia Vairetti, Andrea Ferrigno
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 484 (2024)
Venetoclax is a Bcl-2 homology domain 3 (BH3) mimetic currently approved for the treatment of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML) that has proven to be highly effective in reinstating apoptosis in leukemic cells throug
Externí odkaz:
https://doaj.org/article/b3a6ff91f66c49feaa6d03bcb424a06c
Autor:
Cristian Turato, Mariapia Vairetti, Marta Cagna, Alessandra Biasiolo, Andrea Ferrigno, Santina Quarta, Mariagrazia Ruvoletto, Silvia De Siervi, Patrizia Pontisso, Laura Giuseppina Di Pasqua
Publikováno v:
European Journal of Histochemistry, Vol 66, Iss 4 (2022)
We have investigated the change in SerpinB3 during hepatic ischemia and the potential role of its antiprotease activity in cell protection by the administration of wild-type SerpinB3 (SerpinB3-WT) or active loop-deleted recombinant SerpinB3 protein (
Externí odkaz:
https://doaj.org/article/132dd393be9445019719bfe2e49b6ede
Autor:
Laura Giuseppina Di Pasqua, Clarissa Berardo, Marta Cagna, Barbara Mannucci, Gloria Milanesi, Anna Cleta Croce, Andrea Ferrigno, Mariapia Vairetti
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-14 (2021)
Abstract Background Waiting lists that continue to grow and the lack of organs available for transplantation necessitate the use of marginal livers, such as fatty livers. Since steatotic livers are more susceptible to damage from ischemia and reperfu
Externí odkaz:
https://doaj.org/article/86f756e8e13e4405b19889424d2615e1
Autor:
Anna C. Croce, Andrea Ferrigno, Giuseppina Palladini, Barbara Mannucci, Mariapia Vairetti, Laura G. Di Pasqua
Publikováno v:
Molecules, Vol 28, Iss 9, p 3818 (2023)
The autofluorescence of specific fatty acids, retinoids, and bilirubin in crude serum can reflect changes in liver functional engagement in maintaining systemic metabolic homeostasis. The role of these fluorophores as intrinsic biomarkers of pharmaco
Externí odkaz:
https://doaj.org/article/7416e569fc0a4d9dbb07fdf01b8a233a
Autor:
Lucrezia Irene Maria Campagnoli, Nicoletta Marchesi, Mariapia Vairetti, Alessia Pascale, Andrea Ferrigno, Annalisa Barbieri
Publikováno v:
Cells, Vol 11, Iss 18, p 2827 (2022)
Human aging, a natural process characterized by structural and physiological changes, leads to alterations of homeostatic mechanisms, decline of biological functions, and subsequently, the organism becomes vulnerable to external stress or damage. In
Externí odkaz:
https://doaj.org/article/4406394dce1046e6b1098a3c53e18785
Autor:
Andrea Ferrigno, Clarissa Berardo, Laura Giuseppina Di Pasqua, Marta Cagna, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti
Publikováno v:
European Journal of Histochemistry, Vol 64, Iss 4 (2020)
It has been previously found that the blockade of metabotropic glutamate receptor type 5 (mGluR5) protects against hepatic ischemia/reperfusion injury and acetaminophen toxicity. The role of mGluR5 in NAFLD has not yet been elucidated. Here, we evalu
Externí odkaz:
https://doaj.org/article/0afdce3f76d0428d83c21a3873d2d485
Autor:
Clarissa Berardo, Andrea Ferrigno, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti, Laura Giuseppina Di Pasqua
Publikováno v:
European Journal of Histochemistry, Vol 64, Iss 2 (2020)
Isolated hepatocytes can be obtained from the liver by collagenase infusion, a procedure that could affect cell isolation as well as the integrity of membrane receptors. In this respect we compared metabotropic glutamate subtype 5 receptor (mGluR5) p
Externí odkaz:
https://doaj.org/article/fe362068063d4f258625684697c7301e
Autor:
Giuseppina Palladini, Marta Cagna, Laura Giuseppina Di Pasqua, Luciano Adorini, Anna Cleta Croce, Stefano Perlini, Andrea Ferrigno, Clarissa Berardo, Mariapia Vairetti
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 524 (2022)
We have previously demonstrated that the farnesoid X receptor (FXR) agonist obeticholic acid (OCA) protects the liver via downregulation of hepatic matrix metalloproteinases (MMPs) after ischemia/reperfusion (I/R), which can lead to multiorgan dysfun
Externí odkaz:
https://doaj.org/article/d19198b40c604ad184f40f87acaf108c
Autor:
Laura Giuseppina Di Pasqua, Marta Cagna, Clarissa Berardo, Mariapia Vairetti, Andrea Ferrigno
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 194 (2022)
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are some of the biggest public health challenges due to their spread and increasing incidence around the world. NAFLD is characterized by intrahepatic lipid deposition
Externí odkaz:
https://doaj.org/article/ff10073760784838b11c3db1a2b5e877
Autor:
Saturnino Marco Lupi, Giorgia Olivieri, Jessica Landini, Andrea Ferrigno, Plinio Richelmi, Claudia Todaro, Ruggero Rodriguez y Baena
Publikováno v:
Applied Sciences, Vol 11, Iss 20, p 9449 (2021)
Background: This systematic review and meta-analysis aims to evaluate the effectiveness of antibiotic prophylaxis in the prevention of surgical wound infection (SWI) following mandibular third molar extraction. Methods: A systematic search on electro
Externí odkaz:
https://doaj.org/article/83ff7b992b4646d38fe11dcd0319a233