Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Andre Verheem"'
Autor:
Liza A. Wijler, Danielle A.E. Raats, Andre Verheem, Anna M. denOtter, Helene Rundqvist, Miriam vanDijk, Anne M. May, Onno Kranenburg
Publikováno v:
JCSM Rapid Communications, Vol 5, Iss 1, Pp 117-129 (2022)
Abstract Background Physical activity is associated with a lower risk of colorectal cancer (CRC) and CRC‐specific mortality. However, evidence for a causal relationship between physical activity and disease progression is lacking. Here, we have use
Externí odkaz:
https://doaj.org/article/6cdcace1a9c341049516dcf610708588
Autor:
Onno Kranenburg, Hergen Spits, Julien Villaudy, Madalina Cercel, Miriam Koopman, Cornelis J A Punt, Jamila Laoukili, Andre Verheem, Inne H M Borel Rinkes, Emre Küçükköse, Balthasar A Heesters, Susan van Hal, Sylvia F Boj, Jeanine M L Roodhart
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background The immunogenic nature of metastatic colorectal cancer (CRC) with high microsatellite instability (MSI-H) underlies their responsiveness to immune checkpoint blockade (ICB). However, resistance to ICB is commonly observed, and is associate
Externí odkaz:
https://doaj.org/article/bfcad88f61be41c09cf923011ef6cf7d
Autor:
Onno Kranenburg, Inne H.M. Borel Rinkes, Jan Koster, Benjamin L. Emmink, Nikol Snoeren, Andre Verheem, Kari Trumpi, Susanne van Schelven, Szabolcs Fatrai, Vincent C.J. de Boer, Tijana Borovski, Thomas T. Vellinga
Supplementary tables S1-6. Supplementary table S1 Primers used for RT-qPCR analyses. Supplementary table S2 Clinical variables associated with differences in gene expression among 119 resected liver metastases. Supplementary table S3 613 genes whose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8273ba885637fe642092f2815b95eb39
https://doi.org/10.1158/1078-0432.22460445.v1
https://doi.org/10.1158/1078-0432.22460445.v1
Autor:
Onno Kranenburg, Inne H.M. Borel Rinkes, Jan Koster, Benjamin L. Emmink, Nikol Snoeren, Andre Verheem, Kari Trumpi, Susanne van Schelven, Szabolcs Fatrai, Vincent C.J. de Boer, Tijana Borovski, Thomas T. Vellinga
Purpose: Chemotherapy treatment of metastatic colon cancer ultimately fails due to development of drug resistance. Identification of chemotherapy-induced changes in tumor biology may provide insight into drug resistance mechanisms.Experimental Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279b1c3fb644fc6dbc77d1ed65c39b1e
https://doi.org/10.1158/1078-0432.c.6524493
https://doi.org/10.1158/1078-0432.c.6524493
Autor:
Onno Kranenburg, Inne H.M. Borel Rinkes, Jan Koster, Benjamin L. Emmink, Nikol Snoeren, Andre Verheem, Kari Trumpi, Susanne van Schelven, Szabolcs Fatrai, Vincent C.J. de Boer, Tijana Borovski, Thomas T. Vellinga
Supplementary Figures S1-3. Supplementary figure S1 Cytochrome c oxidase (COX IV) is highly expressed in chemotherapy-treated liver metastases Supplementary figure S2 Expression changes of glycolytic and OXPHOS genes in response to chemotherapy. Supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6976d07ab45114ce81e9399aed0ad4e1
https://doi.org/10.1158/1078-0432.22460448.v1
https://doi.org/10.1158/1078-0432.22460448.v1
Autor:
Onno Kranenburg, Inne H.M. Borel Rinkes, Connie R. Jimenez, Regina Brigelius-Flohé, Ernst J.A. Steller, Andre Verheem, Szabolcs Fatrai, Klaas M. Govaert, Jan Koster, Anna P. Kipp, Jamila Laoukili, Benjamin L. Emmink
Supplementary Figure S3. Loss of GPx2 reduces tumor growth.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6482b720b219d095c40f86bdaf72ce86
https://doi.org/10.1158/0008-5472.22404354
https://doi.org/10.1158/0008-5472.22404354
Autor:
Onno Kranenburg, Inne H.M. Borel Rinkes, Connie R. Jimenez, Regina Brigelius-Flohé, Ernst J.A. Steller, Andre Verheem, Szabolcs Fatrai, Klaas M. Govaert, Jan Koster, Anna P. Kipp, Jamila Laoukili, Benjamin L. Emmink
Supplementary Figure Legends. Legends for Supplementary Figures S1-S6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007978d5c57966a456cf972ddc4153a4
https://doi.org/10.1158/0008-5472.22404369.v1
https://doi.org/10.1158/0008-5472.22404369.v1
Autor:
Onno Kranenburg, Inne H.M. Borel Rinkes, Connie R. Jimenez, Regina Brigelius-Flohé, Ernst J.A. Steller, Andre Verheem, Szabolcs Fatrai, Klaas M. Govaert, Jan Koster, Anna P. Kipp, Jamila Laoukili, Benjamin L. Emmink
Supplementary Materials and Methods. Description of additional methods and procedures used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02bcc0502caedd9e5401a29085b564fc
https://doi.org/10.1158/0008-5472.22404342.v1
https://doi.org/10.1158/0008-5472.22404342.v1
Autor:
Onno Kranenburg, Inne H.M. Borel Rinkes, Connie R. Jimenez, Regina Brigelius-Flohé, Ernst J.A. Steller, Andre Verheem, Szabolcs Fatrai, Klaas M. Govaert, Jan Koster, Anna P. Kipp, Jamila Laoukili, Benjamin L. Emmink
Supplementary Table S4. The epithelial signature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f09bff40c414723f3a300ae9dff0b21
https://doi.org/10.1158/0008-5472.22404327.v1
https://doi.org/10.1158/0008-5472.22404327.v1
Autor:
Onno Kranenburg, Inne H.M. Borel Rinkes, Connie R. Jimenez, Regina Brigelius-Flohé, Ernst J.A. Steller, Andre Verheem, Szabolcs Fatrai, Klaas M. Govaert, Jan Koster, Anna P. Kipp, Jamila Laoukili, Benjamin L. Emmink
Colorectal tumorigenesis is accompanied by the generation of oxidative stress, but how this controls tumor development is poorly understood. Here, we studied how the H2O2-reducing enzyme glutathione peroxidase 2 (GPx2) regulates H2O2 stress and diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3939328a0927a88ca01587801d10f6bd
https://doi.org/10.1158/0008-5472.c.6506580.v1
https://doi.org/10.1158/0008-5472.c.6506580.v1