Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Andre T. Brunetto"'
Autor:
Stan B. Kaye, Jaap Verweij, Josep Tabernero, Jean Charles Soria, Richard H. Wilson, Ruth Plummer, Jeffrey Evans, Emile Voest, Nicolas Penel, Jan H.M. Schellens, Silvia Marsoni, Patrick Schöffski, Andre T. Brunetto, Elisa Gallerani, Gianluca Del Conte, Rafael Morales-Barrera, Philippe A. Cassier, Carlos Gomez-Roca, David Olmos, Victor Moreno García
Supplementary Figure 1. Study flowchart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7875c529173e96dd93bc25c70fbd6fa
https://doi.org/10.1158/1078-0432.22457858.v1
https://doi.org/10.1158/1078-0432.22457858.v1
Autor:
Stan B. Kaye, Jaap Verweij, Josep Tabernero, Jean Charles Soria, Richard H. Wilson, Ruth Plummer, Jeffrey Evans, Emile Voest, Nicolas Penel, Jan H.M. Schellens, Silvia Marsoni, Patrick Schöffski, Andre T. Brunetto, Elisa Gallerani, Gianluca Del Conte, Rafael Morales-Barrera, Philippe A. Cassier, Carlos Gomez-Roca, David Olmos, Victor Moreno García
Supplementary table 1. Main characteristics of patients receiving different dose levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a852e43df12b436b20c772bbd67fc9c
https://doi.org/10.1158/1078-0432.22457855.v1
https://doi.org/10.1158/1078-0432.22457855.v1
Autor:
Sarah P. Blagden, Johann S. de Bono, Richard Wilson, Mohammed M. Dar, Thomas A. Lampkin, Sharon C. Murray, Deborah A. Smith, Alicia J. Allred, Yan Y. Degenhardt, Hanine Medani, Jorge Barriuso, Anne B. Taegtmeyer, Timothy A. Yap, Andre T. Brunetto, Rohini Sharma, Douglas Barker, David Olmos
Supplementary Methods; Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa656e44c9db5425b374f6954cb9ce23
https://doi.org/10.1158/1078-0432.22441227
https://doi.org/10.1158/1078-0432.22441227
Autor:
Stan B. Kaye, Jaap Verweij, Josep Tabernero, Jean Charles Soria, Richard H. Wilson, Ruth Plummer, Jeffrey Evans, Emile Voest, Nicolas Penel, Jan H.M. Schellens, Silvia Marsoni, Patrick Schöffski, Andre T. Brunetto, Elisa Gallerani, Gianluca Del Conte, Rafael Morales-Barrera, Philippe A. Cassier, Carlos Gomez-Roca, David Olmos, Victor Moreno García
Supplementary table 3. Multivariate model for Overall Survival (Cytotoxic Agents)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3704753b656bbabbb08623df6d9bdfee
https://doi.org/10.1158/1078-0432.22457849.v1
https://doi.org/10.1158/1078-0432.22457849.v1
Autor:
Stan B. Kaye, Jaap Verweij, Josep Tabernero, Jean Charles Soria, Richard H. Wilson, Ruth Plummer, Jeffrey Evans, Emile Voest, Nicolas Penel, Jan H.M. Schellens, Silvia Marsoni, Patrick Schöffski, Andre T. Brunetto, Elisa Gallerani, Gianluca Del Conte, Rafael Morales-Barrera, Philippe A. Cassier, Carlos Gomez-Roca, David Olmos, Victor Moreno García
Introduction: Because a dose–response relationship is characteristic of conventional chemotherapy, this concept is widely used for the development of novel cytotoxic (CTX) drugs. However, the need to reach the MTD to obtain optimal benefit with mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8493d0c4d40757375b023a3cc460671b
https://doi.org/10.1158/1078-0432.c.6523727.v1
https://doi.org/10.1158/1078-0432.c.6523727.v1
Autor:
Stan B. Kaye, Jaap Verweij, Josep Tabernero, Jean Charles Soria, Richard H. Wilson, Ruth Plummer, Jeffrey Evans, Emile Voest, Nicolas Penel, Jan H.M. Schellens, Silvia Marsoni, Patrick Schöffski, Andre T. Brunetto, Elisa Gallerani, Gianluca Del Conte, Rafael Morales-Barrera, Philippe A. Cassier, Carlos Gomez-Roca, David Olmos, Victor Moreno García
Supplementary table 2. Multivariate model for overall survival (Molecularly Targeted Agents).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac98c58d500bc6de6409f08f583f70b
https://doi.org/10.1158/1078-0432.22457852.v1
https://doi.org/10.1158/1078-0432.22457852.v1
Autor:
Sarah P. Blagden, Johann S. de Bono, Richard Wilson, Mohammed M. Dar, Thomas A. Lampkin, Sharon C. Murray, Deborah A. Smith, Alicia J. Allred, Yan Y. Degenhardt, Hanine Medani, Jorge Barriuso, Anne B. Taegtmeyer, Timothy A. Yap, Andre T. Brunetto, Rohini Sharma, Douglas Barker, David Olmos
Purpose: GSK461364 is an ATP-competitive inhibitor of polo-like kinase 1 (Plk1). A phase I study of two schedules of intravenous GSK461364 was conducted.Experimental Design: GSK461364 was administered in escalating doses to patients with solid malign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff23bf4b14372b8aa854f554ab505b1
https://doi.org/10.1158/1078-0432.c.6518349
https://doi.org/10.1158/1078-0432.c.6518349
Autor:
Maria Eduarda Battistella, Natália Hogetop Freire, Bruno Toson, Matheus Dalmolin, Marcelo A. C. Fernandes, Isadora D. Tassinari, Mariane Jaeger, André T. Brunetto, Algemir L. Brunetto, Lauro Gregianin, Caroline Brunetto de Farias, Rafael Roesler
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 3990-4003 (2024)
Retinoic acid (RA) regulates stemness and differentiation in human embryonic stem cells (ESCs). Ewing sarcoma (ES) is a pediatric tumor that may arise from the abnormal development of ESCs. Here we show that RA impairs the viability of SK-ES-1 ES cel
Externí odkaz:
https://doaj.org/article/b0e933e8b0a2419ca47b31f833d979cc
Autor:
Maja J.A. de Jonge, Jan H.M. Schellens, Diane A.J. van der Biessen, Andre T. Brunetto, Agnes Jager, Johann S. de Bono, Joo Ern Ang, Martijn P. Lolkema, Jacques De Greve, Hendrik-Tobias Arkenau, Ruud van der Noll, Ilian Tchakov, Jos H. Beijnen, Marja Mergui-Roelvink, Serena Marchetti
Publikováno v:
Investigational New Drugs, 38(4), 1096-1107. Kluwer Academic
Investigational New Drugs, 38. Kluwer Academic Publishers
Investigational New Drugs, 38. Kluwer Academic Publishers
Background In the first part of this extensive phase I study (NCT00516724), continuous olaparib twice daily (bid) with carboplatin and/or paclitaxel resulted in myelosuppression and dose modifications. Here, we report the safety, tolerability, and ef
Autor:
Galina Kuznetsov, Alastair Greystoke, Khin Than Myint, Lucy Lee, Malcolm R Ranson, Karen Wood, Gennaro Daniele, Emma Dean, Andre T. Brunetto, B.D.L. Heras, Matthew G Krebs, L Rhoda Molife, Montserrat Blanco-Codesido
Publikováno v:
Clinical Cancer Research. 20:6284-6294
Purpose: Receptor tyrosine kinases c-Met and Ron transduce signals regulating cell migration and matrix invasion. This phase I dose-escalation trial tested golvatinib, a highly potent, small-molecule, ATP-competitive inhibitor of c-Met and multiple m