Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andre Spiering"'
Autor:
Andre Spiering, Dario Anselmetti, Michael Mayer, Lukas Galla, Sebastian Knust, Karsten Gall, Adam R. Hall, Andy Sischka, Andreas Meyer, Peter Reimann
Publikováno v:
ResearcherID
To quantify minute forces with sub-pN precision on single molecules translocating through nanopores we developed real-time video-based 3D force detection for an optical tweezers system.With this setup, we investigate the threading force on a single d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2237dd880740ca63d796ed2957030f
https://doi.org/10.1016/j.bpj.2015.11.2763
https://doi.org/10.1016/j.bpj.2015.11.2763
Autor:
Armin Gölzhäuser, Peter Reimann, Michael Mayer, Lukas Galla, Andy Sischka, Sebastian Knust, Adam R. Hall, André Beyer, Andreas Meyer, Dario Anselmetti, Andre Spiering
Publikováno v:
The Analyst. 140(14)
We investigated experimentally and theoretically the translocation forces when a charged polymer is threaded through a solid-state nanopore and found distinct dependencies on the nanopore diameter as well as on the nano membrane material chemistry. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8212f47004f851694c110a4c22eb2bf
https://pubmed.ncbi.nlm.nih.gov/25768647
https://pubmed.ncbi.nlm.nih.gov/25768647
Autor:
Thomas Jany, Andy Sischka, Susan Haji Samo, Mareike Dieding, Hartmut Bögge, Anja Stammler, Andre Spiering, Gabriele Fischer von Mollard, Claudia Horstmann née Gruschka, Dario Anselmetti, Thorsten Glaser, Ying Wang, Alexander Moreth
Publikováno v:
Inorganic chemistry. 54(6)
The mechanism of the cytotoxic function of cisplatin and related anticancer drugs is based on their binding to the nucleobases of DNA. The development of new classes of anticancer drugs requires establishing other binding modes. Therefore, we perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880dcffd7be774b2d1b1ec381f943e44
https://pubmed.ncbi.nlm.nih.gov/25650993
https://pubmed.ncbi.nlm.nih.gov/25650993
Autor:
Armin Gölzhäuser, Andy Sischka, Henning Vieker, Andre Spiering, Sebastian Knust, André Beyer, Katja Tönsing, Dario Anselmetti
Publikováno v:
The Review of scientific instruments. 83(10)
For measuring the minute forces exerted on single molecules during controlled translocation through nanopores with sub-piconewton precision, we have developed a video-based axial force detection and analysis system for optical tweezers. Since our det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759df0b3c9edd7175fc7420bce2e721d
https://pubmed.ncbi.nlm.nih.gov/23126771
https://pubmed.ncbi.nlm.nih.gov/23126771
Autor:
Katja Tönsing, Peter Reimann, Andre Spiering, L. Redondo, Sebastian Knust, André Beyer, Sebastian Getfert, Karsten Rott, Dario Anselmetti, Andy Sischka
The controlled translocation of a single, double-stranded DNA (dsDNA) through a solid-state nanopore (NP) with optical tweezers (OT) is described in the presence of an electric field under buffer conditions. Upon threading dsDNA complexed by single p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07c95c33dfa26b0654ec1d009d2fbb84
https://doi.org/10.1039/9781849735278-00099
https://doi.org/10.1039/9781849735278-00099
We study the translocation dynamics of a single protein molecule attached to a double-stranded DNA that is threaded through a solid-state nanopore by optical tweezers and an electric field (nanopore force spectroscopy). We find distinct asymmetric an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e88c42b52cd60e2ea06564c8f616209
https://doi.org/10.1021/nl201541y
https://doi.org/10.1021/nl201541y
Autor:
Andre Spiering, Karl-Josef Dietz, Dario Anselmetti, Andy Sischka, Miriam Laxa, Maryam Khaksar, Janine König
Publikováno v:
Journal of Physics: Condensed Matter. 22:454121
We investigated the threading and controlled translocation of individual lambda-DNA (lambda-DNA) molecules through solid-state nanopores with piconewton force sensitivity, millisecond time resolution and picoampere ionic current sensitivity with a se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201019518b2ff2f8db928b62423835e2
https://doi.org/10.1088/0953-8984/22/45/454121
https://doi.org/10.1088/0953-8984/22/45/454121
Publikováno v:
Nano Letters; Jul2011, Vol. 11 Issue 7, p2978-2982, 5p
Autor:
Andre Spiering, Katja Tönsing, Ulf Diederichsen, Andy Sischka, Dario Anselmetti, Christoph Kleimann, Norbert Sewald
Publikováno v:
Biophysical Journal. (10):2780-2784
The binding kinetics of the intercalative binding of Triostin A to λ-DNA was investigated by measuring the force extension response of the DNA-ligand complexes with an optical tweezers system. These force response curves, containing the information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed67eba8734dc0056121304d0513b829