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Akademický článek

From Modules to Networks: a Systems-Level Analysis of the Bacitracin Stress Response in Bacillus subtilis

Autor: Hannah Piepenbreier, Andre Sim, Carolin M. Kobras, Jara Radeck, Thorsten Mascher, Susanne Gebhard, Georg Fritz

Publikováno v: mSystems, Vol 5, Iss 1 (2020)

ABSTRACT Bacterial resistance against antibiotics often involves multiple mechanisms that are interconnected to ensure robust protection. So far, the knowledge about underlying regulatory features of those resistance networks is sparse, since they ca

Externí odkaz: https://doaj.org/article/bad63c3f2cbc483f965bbdb5448c3e63

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Akademický článek

Experience of Service Questionnaire (ESQ) in children and adolescents: factor structure, reliability, validity, item parameters and interpretability of the parent version for practical use in Greece

Autor: Konstantinos Kotsis, Andromachi Mitropoulou, Alexandra Tzotzi, Lauro Estivalete Marchionatti, Mauricio Scopel Hoffmann, Julia Luiza Schafer, Caio B. Casella, André Simioni, Katerina Papanikolaou, Maria Basta, Aspasia Serdari, Anastasia Koumoula, Giovanni Abrahão Salum

Publikováno v: Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-10 (2024)

Abstract Background Health systems need tools to assess patient’s experience of service, but existing tools lack reliability and validity assessment. Our aim is to investigate the factor structure, reliability, validity, item parameters and interpr

Externí odkaz: https://doaj.org/article/2c1a5c03bf1c4d328b425d872ee6c9f2

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Akademický článek

Implementation of spirometry screening for post-tuberculosis lung disease (PTLD) among adolescents and adults enrolled within the National Tuberculosis Control Program of Carmelo Hospital in Chókwè District, Mozambique: A hybrid type III effectiveness-implementation study protocol

Autor: Harriett Myers, Bartolomeu Chongo, Jerry S. Zifodya, Isabel Zacaria, Estevão Machava, André Simango, Gustavo Amorim, Elzier Mavume-Mangunyane, Rogério Chiau, Kathryn T. Kampa, Tavares Madede, Mohsin Sidat, Troy D. Moon

Publikováno v: BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-11 (2024)

Abstract Background Despite receiving adequate treatment, many tuberculosis (TB) survivors are left with post-tuberculosis complications, possibly due to lung tissue damage incurred during the active period of the disease. Current TB programs worldwi

Externí odkaz: https://doaj.org/article/62d46221e4b04599ba363317f67886ed

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Context-Aware Transcript Quantification from Long Read RNA-Seq data with Bambu

Autor: Ying Chen, Andre Sim, Yuk Kei Wan, Keith Yeo, Joseph Jing Xian Lee, Min Hao Ling, Michael I. Love, Jonathan Göke

Most approaches to transcript quantification rely on fixed reference annotations. However, the transcriptome is dynamic, and depending on the context, such static annotations contain inactive isoforms for some genes while they are incomplete for othe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1451117cc38e5b41a2b36678e157a2b0
https://doi.org/10.1101/2022.11.14.516358

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Akademický článek

The mental health care system for children and adolescents in Greece: a review and structure assessment

Publikováno v: Frontiers in Health Services, Vol 4 (2024)

BackgroundThe mental health system in Greece faces challenges to complete its transition to a community-oriented model, having significant concerns for child and adolescent care due to lower coverage and service gaps. This component of the mental hea

Externí odkaz: https://doaj.org/article/6c0bbe283306478ba46cd954f6047029

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Antisense RNAs Influence Promoter Usage of Their Counterpart Sense Genes in Cancer

Autor: Max Wei Jie Lim, Omer An, Fernando Bellido Molias, Jonathan Göke, Jasmin Xin Jia Teo, Yangyang Song, Chen Ying, Andre Sim, Leilei Chen, Ka Wai Leong, Vanessa Hui En Ng

Publikováno v: Cancer research. 81(23)

Multiple noncoding natural antisense transcripts (ncNAT) are known to modulate key biological events such as cell growth or differentiation. However, the actual impact of ncNATs on cancer progression remains largely unknown. In this study, we identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b972955bad29d37a5d069418fcd3db
https://pubmed.ncbi.nlm.nih.gov/34649947

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Akademický článek

Translation and cross-cultural adaptation of seventeen widely-used assessment instruments for child and adolescent mental health in Greece

Publikováno v: Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-10 (2024)

Abstract Background In the context of Greece, many instruments measuring constructs pertinent to child and adolescent mental health lacked a locally-validated, freely-available version. As part of a nationwide survey, we translated and cross-cultural

Externí odkaz: https://doaj.org/article/098c8054b8fd4f11943984c42247f6d1

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From Modules to Networks: a Systems-Level Analysis of the Bacitracin Stress Response in Bacillus subtilis

Autor: Thorsten Mascher, Jara Radeck, Georg Fritz, Hannah Piepenbreier, Andre Sim, Susanne Gebhard, Carolin M. Kobras

Publikováno v: mSystems
mSystems, Vol 5, Iss 1, p e00687-19 (2020)
Piepenbreier, H, Sim, A, Kobras, C M, Radeck, J, Mascher, T, Gebhard, S & Fritz, G 2020, ' From modules to networks: A systems-level analysis of the bacitracin stress response in Bacillus subtilis ', mSystems, vol. 5, no. 1, e00687-19 . https://doi.org/10.1128/mSystems.00687-19
mSystems, Vol 5, Iss 1 (2020)

Antibiotic resistance poses a major threat to global health, and systematic studies to understand the underlying resistance mechanisms are urgently needed. Although significant progress has been made in deciphering the mechanistic basis of individual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3966a2eb352146841bcfa909921f11
https://pubmed.ncbi.nlm.nih.gov/32019833

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