Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andre Schmandke"'
Autor:
Richard Manns, Andre Schmandke, Antonio Schmandke, Prem Jareonsettasin, Geoffrey Cook, Martin E Schwab, Christine Holt, Roger Keynes
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86820 (2014)
The protein Nogo-A regulates axon growth in the developing and mature nervous system, and this is carried out by two distinct domains in the protein, Nogo-A-Δ20 and Nogo-66. The differences in the signalling pathways engaged in axon growth cones by
Externí odkaz:
https://doaj.org/article/b14b80fcda314c738cc6bc35495e3ef2
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78212 (2013)
BACKGROUND:Adhesion dependent mechanisms are increasingly recognized to be important for a wide range of biological processes, diseases and therapeutics. This has led to a rising demand of pharmaceutical modulators. However, most currently available
Externí odkaz:
https://doaj.org/article/1f4f82896f894bffae3d1d4ef85c42d3
Autor:
Andreas von Deimling, Jan Medenbach, Kai Schönig, Christiane B. Knobbe-Thomsen, Marcel Kool, Stefan Pusch, Andreas Hentschel, Himanshu Soni, Martin E. Schwab, Giulia Rossetti, Andre Schmandke, Michael O. Breckwoldt, Björn Tews, Martin Bendszus, Julia Bode, Thomas Krüwel, Norman Mack, Robert Ahrends, Christel Herold-Mende, Bernd Fischer, Peter Wirthschaft, Fabio Dietrich, Guido Reifenberger
Publikováno v:
Acta Neuropathologica, 138 (2)
Acta neuropathologica 138(2), 275-293 (2019). doi:10.1007/s00401-019-02021-z
Acta Neuropathologica
Acta neuropathologica 138(2), 275-293 (2019). doi:10.1007/s00401-019-02021-z
Acta Neuropathologica
Glioblastomas strongly invade the brain by infiltrating into the white matter along myelinated nerve fiber tracts even though the myelin protein Nogo-A prevents cell migration by activating inhibitory RhoA signaling. The mechanisms behind this long-k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3818752eba3580da94a85c590b6f6a3
Autor:
Anissa Kempf, Rafael D. Fritz, Zorica Ristic, Martin E. Schwab, Antonio Schmandke, Andrea M Kaelin, Valentina Grande, Enrica Boda, Jessica C. F. Kwok, James W. Fawcett, Annalisa Buffo, Olivier Pertz, Bjoern Tews, Andre Schmandke
Heparan sulfate proteoglycans (HSPGs) critically modulate adhesion-, growth-, and migration-related processes. Here, we show that the transmembrane protein, Nogo-A, inhibits neurite outgrowth and cell spreading in neurons and Nogo-A-responsive cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35343ba5e049efb7e87ce24505b37cac
Publikováno v:
CELL ADHESION & MIGRATION
Cell Adhesion & Migration
Cell Adhesion & Migration
Next to its well-established role as a myelin-associated neurite growth-inhibitory protein, Nogo-A more recently has emerged as an important modulator of adhesion and migration. However, Nogo-A’s function in adhesion and migration is diverse and st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e925d97bc14d8775e692fcf57428ebc
Autor:
Jonathan Sigworth, William B. J. Cafferty, Stephen M. Strittmatter, Shuh Narumiya, Andre Schmandke, Antonio Schmandke, Philip Duffy
Publikováno v:
The Journal of Neuroscience. 29:15266-15276
Rho GTPases are thought to mediate the action of several axonal growth inhibitors in the adult brain and spinal cord. RhoA has been targeted pharmacologically in both humans and animals to promote neurite outgrowth and functional recovery following C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00643e14a513e0263defa54ae166685d
https://doi.org/10.1523/jneurosci.4650-09.2009
https://doi.org/10.1523/jneurosci.4650-09.2009
Publikováno v:
The Neuroscientist. 13:454-469
Rho-associated protein kinases (ROCKs) play key roles in mediating the control of the actin cytoskeleton by Rho family GTPases in response to extracellular signals. Such signaling pathways contribute to diverse neuronal functions from cell migration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d11b3b82f5025ea808b8ae5fdc80d80
https://doi.org/10.1177/1073858407303611
https://doi.org/10.1177/1073858407303611
Publikováno v:
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 20(4)
Initially discovered as a potent neurite outgrowth inhibitor in the central nervous system (CNS), Nogo-A has emerged as a multifunctional protein. Involvement of this protein has been demonstrated in numerous developmental processes, ranging from cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8af4c1b7beed560b7d38dfa14ebb39b9
https://pubmed.ncbi.nlm.nih.gov/24402613
https://pubmed.ncbi.nlm.nih.gov/24402613
Publikováno v:
The Neuroscientist
Initially discovered as a potent neurite outgrowth inhibitor in the central nervous system (CNS), Nogo-A has emerged as a multifunctional protein. Involvement of this protein has been demonstrated in numerous developmental processes, ranging from cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2d37fc9d4d84036df5311d0ec620be