Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andre S. Bowers"'
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68929 (2013)
OBJECTIVE: To determine differences in TNF-α, IL-1β, IL-10, sICAM-1 concentrations, leg hypoxia and whole blood viscosity (WBV) at shear rates of 46 sec(-1) and 230 sec(-1) in persons with homozygous S sickle cell disease (SCD) with and without chr
Externí odkaz:
https://doaj.org/article/812361f3fa8142d28d59e1933c507762
Publikováno v:
International Journal of Angiology. 27:035-038
Background There is no consensus regarding the role of red blood cell (RBC) aggregation in the pathogenesis of leg ulcers (LUs) in sickle cell disease (SCD). Objectives We sought to evaluate whether the cross-sectional determination of RBC aggregatio
Publikováno v:
Clinical Hemorheology and Microcirculation. 64:199-204
Previous reports differ as to whether a decreased elongation index (EI), a proxy for red blood cell (RBC) deformability, is associated with leg ulcers (LU) in people with homozygous sickle cell disease (SCD). We sought to determine whether erythrocyt
Publikováno v:
Clinical Hemorheology and Microcirculation. 47:253-260
The determination of an optimal haematocrit (H0) has important clinical implications if such a level can be attained, and more importantly, maintained. This is defined as a haematocrit level, above or below which oxygen delivery is deleteriously affe
Publikováno v:
Clinical Hemorheology and Microcirculation. 40:303-309
Sickle cell disease is characterized by altered blood rheology due to a reduced haematocrit and a resulting lowered viscosity. Oxygen carriage, and consequently oxygen delivery, may be deleteriously affected if the haematocrit reduction is such as to
Autor:
Andre S. Bowers, Philippe Connes, Vanessa Cumming, Marie-Dominique Hardy-Dessources, Marc Romana, Jean-Claude Barthélémy, Jennifer Knight-Madden, Danitza Nebor, H. L. Reid, Jacques Elion, Marvin Reid, Olivier Hue
Publikováno v:
Haematologica. 96(11)
Recent evidence suggests that autonomic nervous system activity could be involved in the pathophysiology of sickle cell disease, but it is unclear whether differences in autonomic nervous system activity are detectable during steady state in patients
Publikováno v:
British journal of biomedical science. 66(3)
One of the common complications of sickle cell disease is the vaso-occlusive crisis or sickle cell crisis which could result in impaired oxygen delivery to the tissues. This study investigates the oxygen delivery index (ODI) in 38 patients with homoz