Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Andre M. Pilon"'
Autor:
David M. Bodine, Jose Sangerman, Murat O. Arcasoy, Holly K. Dressman, Yelena Maksimova, Serena E. Vayda, Andre M. Pilon, Patrick G. Gallagher
Publikováno v:
Molecular and Cellular Biology. 28:7394-7401
Erythroid Krüppel-like factor (EKLF) is a Krüppel-like transcription factor identified as a transcriptional activator and chromatin modifier in erythroid cells. EKLF-deficient (Eklf(-/-)) mice die at day 14.5 of gestation from severe anemia. In thi
Autor:
Elio F. Vanin, Mitchell E. Horwitz, Gilda F. Linton, Harry L. Malech, Mindy Anderson-Cohen, Sebastian Brenner, Patrick Kelly, Andre M. Pilon, Kevin L. Holmes, Narda L. Whiting-Theobald, David M. Bodine
Publikováno v:
Blood. 102:2789-2797
In previous studies amphotropic MFGS-gp91phox (murine onco-retrovirus vector) was used in a clinical trial of X-linked chronic granulomatous disease (X-CGD) gene therapy to achieve transient correction of oxidase activity in 0.1% of neutrophils. We l
Autor:
Andre M. Pilon, John C. McKew
The Therapeutics for Rare and Neglected D iseases (TRND) program (see: http://ncats.nih.gov/trnd.html) seeks to encourage and speed the development of new treatments for diseases of limited commercial interest to the biopharmaceutical industry. Faced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c631bfd9bcccacde0a07137643c451
https://europepmc.org/articles/PMC3814034/
https://europepmc.org/articles/PMC3814034/
Autor:
Stephen Wincovitch, Subramanian S. Ajay, Laurie A. Steiner, Swathi Ashok Kumar, Stacie M. Anderson, Patrick G. Gallagher, Andre M. Pilon, Praveen F. Cherukuri, Ross C. Hardison, James C. Mullikin, David M. Bodine, Elliott H. Margulies
Publikováno v:
Blood. 118(17)
Erythropoiesis is dependent on the activity of transcription factors, including the erythroid-specific erythroid Kruppel-like factor (EKLF). ChIP followed by massively parallel sequencing (ChIP-Seq) is a powerful, unbiased method to map trans-factor
Autor:
Patrick G. Gallagher, Subramanian S. Ajay, Andre M. Pilon, Hatice Ozel Abaan, David M. Bodine, Elliott H. Margulies
Publikováno v:
Blood. 114:565-565
Abstract 565 Erythroid Kruppel-Like Factor (EKLF; KLF1) is the founding member of the Kruppel family of C2H2 zinc finger transcription factors. First identified as an activator of the beta-globin locus, EKLF facilitates chromatin remodeling and trans
Autor:
David M. Bodine, Elliott H. Margulies, Patrick G. Gallagher, Andre M. Pilon, Dewang Zhou, Hatice Ozel Abaan, Tim M. Townes, Abbie M. Frederick, Amy Werner Allen
Publikováno v:
Blood. 112:283-283
Erythroid Kruppel-Like Factor (EKLF; KLF1) is the founding member of the Kruppel family of transcription factors, with 3 C2H2 zinc-fingers that bind a 9-base consensus sequence (NCNCNCCCN). The functions of EKLF, first identified as an activator of t
Publikováno v:
Blood. 110:1234-1234
Erythroid Krüppel-Like Factor (EKLF) is the founding member of the mammalian Krüppel subfamily of transcription factors with 3 C2H2-type zinc fingers. In mice, loss of EKLF is lethal at day 14 of gestation (dE14), due to severe anemia. To study t
Autor:
Holly K. Dressman, Murat O. Arcasoy, James J. Bieker, Andre M. Pilon, Serena E. Vayda, David M. Bodine, Patrick G. Gallagher
Publikováno v:
Blood Cells, Molecules, and Diseases. 38:172
Autor:
Clara Wong, Patrick G. Gallagher, Ashley N. Owen, Nancy E. Seidel, Amanda P. Cline, Andre M. Pilon, David M. Bodine
Publikováno v:
Blood Cells, Molecules, and Diseases. 38:165
Autor:
James J. Bieker, Andre M. Pilon, Patrick G. Gallagher, Holly K. Dressman, Serena E. Vayda, Murat O. Arcasoy, David M. Bodine
Publikováno v:
Blood. 108:84-84
Mice deficient in the erythroid transcription factor EKLF die ~dE14 from severe anemia, attributed to decreased β-globin expression. Recent reports using microarray analyses indicate that expression of numerous genes is perturbed in erythroid cells