Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Andre M. Beauchemin"'
Autor:
Jean-François Vincent-Rocan, Indee Ranasinghe, Philippe Lemire, Andre M. Beauchemin, Amanda Bongers, Alyssa Perozzo
Publikováno v:
Organic Letters. 18:3778-3781
Various nitrogen-substituted iso(thio)cyanates engage in [3 + 2]-cycloaddition reactions to form azomethine imines containing triazolone, triazole-thione, and pyrazole-thione cores. First, iminoisothiocyanates are shown to undergo aminothiocarbonylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2eb46b845cd82dfe024721d3fffc9f
https://doi.org/10.1021/acs.orglett.6b01788
https://doi.org/10.1021/acs.orglett.6b01788
Autor:
Jean-François Vincent-Rocan, Christian Clavette, Andre M. Beauchemin, Ryan A. Ivanovich, Serge I. Gorelsky, Jean‐Gregoire Roveda
Publikováno v:
Chemistry - A European Journal. 22:7906-7916
The ubiquity of nitrogen heterocycles in biologically active molecules challenges synthetic chemists to develop a variety of tools for their construction. While developing metal-free hydroamination reactions of hydrazine derivatives, it was discovere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b14e79e875c5550b7d2a582d132797
https://doi.org/10.1002/chem.201600574
https://doi.org/10.1002/chem.201600574
Publikováno v:
Organic Letters. 18:658-661
Cascade reactions for the synthesis of 1,2,4-triazinones and 5-aminopyridazinones are reported using α-ketocarbazones as N-isocyanate precursors and exploiting the divergent reactivity observed with primary and secondary amines. Triazinones were for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b6693c680c005328d49fb38ef6ef94
https://doi.org/10.1021/acs.orglett.5b03590
https://doi.org/10.1021/acs.orglett.5b03590
Autor:
Julien Bejjani, Ryan A. Ivanovich, Kyle Leckett, Jean-François Vincent-Rocan, Andre M. Beauchemin, Christian Clavette
Publikováno v:
Chemical Science. 7:315-328
In contrast to normal C-substituted isocyanates, nitrogen-substituted isocyanates (N-isocyanates) are rare. Their high reactivity and amphoteric/ambident nature has prevented the scientific community from exploiting their synthetic potential. Recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dfd726f420485414b4252666dfed78f
https://doi.org/10.1039/c5sc03197d
https://doi.org/10.1039/c5sc03197d
Publikováno v:
Organic Letters. 17:4898-4901
A one-pot sequence for the synthesis of aza-diketopiperazines is reported, involving carbazate acylation with chloroacetyl chloride, SN2 with a primary amine, N-isocyanate formation, and cyclization. Nitrogen-substituted isocyanates (N-isocyanates) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c4d90cc4597a18624ac83fe0635ca2
https://doi.org/10.1021/acs.orglett.5b02464
https://doi.org/10.1021/acs.orglett.5b02464
Publikováno v:
Chemistry - A European Journal. 21:3886-3890
Nitrogen-substituted isocyanates are rarely utilized but powerful building blocks for the development of cascade reactions in heterocyclic synthesis. These reactive amphoteric intermediates can be accessed in situ via an equilibrium that allows contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501d6fec2d6cdca61203bd386c7f1ee8
https://doi.org/10.1002/chem.201405648
https://doi.org/10.1002/chem.201405648
Autor:
Indee Ranasinghe, Andre M. Beauchemin, Jean-François Vincent-Rocan, Amanda Bongers, Philippe Lemire, Alyssa Perozzo
Publikováno v:
ChemInform. 47
Various nitrogen-substituted iso(thio)cyanates engage in [3 + 2]-cycloaddition reactions to form azomethine imines containing triazolone, triazole–thione, and pyrazole–thione cores. First, iminoisothiocyanates are shown to undergo aminothiocarbon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff83c9b0228b9e8cf902e7098722a5fc
https://doi.org/10.1002/chin.201651031
https://doi.org/10.1002/chin.201651031
Publikováno v:
ChemInform. 47
A copper-catalyzed cascade reaction of in situ generated nitrogen-substituted isocyanates (N-isocyanates) and 2-iodoanilines has been developed. The cascade relies on the base-catalyzed substitution of masked N-isocyanates, followed by Cu(I)-catalyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a6e04ef13b35856d2eb66de61dc1d55
https://doi.org/10.1002/chin.201648142
https://doi.org/10.1002/chin.201648142
Autor:
Christian Clavette, Andre M. Beauchemin, Ryan A. Ivanovich, Jean-François Vincent-Rocan, Serge I. Gorelsky, Jean‐Gregoire Roveda
Publikováno v:
ChemInform. 47
The ubiquity of nitrogen heterocycles in biologically active molecules challenges synthetic chemists to develop a variety of tools for their construction. While developing metal-free hydroamination reactions of hydrazine derivatives, it was discovere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::694695cf5fa62d13db7caaafe245185b
https://doi.org/10.1002/chin.201643111
https://doi.org/10.1002/chin.201643111
Publikováno v:
Organic letters. 18(14)
A copper-catalyzed cascade reaction of in situ generated nitrogen-substituted isocyanates (N-isocyanates) and 2-iodoanilines has been developed. The cascade relies on the base-catalyzed substitution of masked N-isocyanates, followed by Cu(I)-catalyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58861b389f81f34d5b730d61cdf00af7
https://pubmed.ncbi.nlm.nih.gov/27341005
https://pubmed.ncbi.nlm.nih.gov/27341005