Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Andre Lopes Fuly"'
Autor:
Camila Castro-Pinheiro, Luiz Carlos Simas Pereira Junior, Eladio Flores Sanchez, Ana Cláudia Rodrigues da Silva, Corinna A. Dwan, Samuel S. Karpiniec, Alan Trevor Critchley, Andre Lopes Fuly
Publikováno v:
Toxins, Vol 16, Iss 4, p 188 (2024)
Background: Snakebite envenomation (SBE) causes diverse toxic effects in humans, including disability and death. Current antivenom therapies effectively prevent death but fail to block local tissue damage, leading to an increase in the severity of en
Externí odkaz:
https://doaj.org/article/779b18dc1a044a6cb5587eb1cb985c7d
Autor:
Guilherme Muricy, Eládio Flores Sanchez, Suzi Ribeiro, Eduardo Coriolano de Oliveira, Camila Nunes Faioli, Thaisa Francielle Souza Domingos, Andre Lopes Fuly
Publikováno v:
Toxins, Vol 5, Iss 10, Pp 1799-1813 (2013)
Snakebites are a health problem in many countries due to the high incidence of such accidents. Antivenom treatment has regularly been used for more than a century, however, this does not neutralize tissue damage and may even increase the severity and
Externí odkaz:
https://doaj.org/article/c219f8403ff744269fe0c0b055b09ad9
Autor:
Suzi Meneses Ribeiro, Fredy Ortiz-Ramirez, Diana Negrao Cavalcanti, Laura de Andrade Moura, Guilherme Muricy, Valeria Laneuville Teixeira, Andre Lopes Fuly
Publikováno v:
Marine Drugs, Vol 9, Iss 8, Pp 1346-1358 (2011)
The ischemic disorders, in which platelet aggregation and blood coagulation are involved, represent a major cause of disability and death worldwide. The antithrombotic therapy has unsatisfactory performance and may produce side effects. So, there is
Externí odkaz:
https://doaj.org/article/bd4525210cd1405ab98873d62ebb3cb2
Autor:
Ana Cláudia Rodrigues da Silva, Maria Eugenia Rabello Duarte, Miguel Daniel Noseda, Luciana Garcia Ferreira, Juliana Emanuela Fogari Cassolato, Eladio Flores Sanchez, Andre Lopes Fuly
Publikováno v:
Marine Drugs, Vol 16, Iss 11, p 412 (2018)
Worldwide, snakebites have serious implications for human health. The administration of antivenom is the official treatment used to reverse the toxic activities of envenomation. However, this therapy is not efficient to treat the local effects, leadi
Externí odkaz:
https://doaj.org/article/fcf0b0e1c17049d6bca9744232d2d0c9
Autor:
Nathalia Gugick Pinheiro, Daniel Tadeu Gomes Gonzaga, Aldo Rodrigues da Silva, Andre Lopes Fuly, Natalia Lidmar von Ranke, Carlos Rangel Rodrigues, Betina Quintanilha Magalhães, Julianne Soares Pereira, Paulo Anastácio F. Pacheco, Ana Cláudia Silva, Vitor Francisco Ferreira, Fernando de Carvalho da Silva, Robson Xavier Faria
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
The present study aimed to investigate five triazole compounds as P2X7R inhibitors and evaluate their ability to reduce acute inflammation in vivo.The synthetic compounds were labeled 5e, 8h, 9i, 11, and 12.We administered 500 ng/kg triazole analogs
Autor:
Nayanna de Mello Amorim, Luiz Carlos Simas Pereira Junior, Eladio Flores Sanchez, Gabriel Alves de Aquino, Vitor Francisco Ferreira, Sabrina Baptista Ferreira, André Lopes Fuly, Eduardo Coriolano de Oliveira
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2023)
Abstract Snake envenomation is a public health problem, and while serum therapy prevents death, the local effects of venoms can lead to amputations or morbidities. Thus, alternative treatments deserve attention. In this study, we tested eight derivat
Externí odkaz:
https://doaj.org/article/d10c74758be440cd83e31ad05407689e
Autor:
Jenifer Frouche de Souza, Eduardo Coriolano de Oliveira, Ana Cláudia Rodrigues da Silva, Vagner Pereira da Silva, Maria Auxiliadora Coelho Kaplan, Maria Raquel Figueiredo, Eladio Flores Sanchez, André Lopes Fuly
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112285- (2021)
Externí odkaz:
https://doaj.org/article/52b90bba9c104314955365e9898d0d7d
Autor:
Jenifer Frouche de Souza, Eduardo Coriolano de Oliveira, Ana Cláudia Rodrigues da Silva, Vagner Pereira da Silva, Maria Auxiliadora Coelho Kaplan, Maria Raquel Figueiredo, Eladio Flores Sanchez, André Lopes Fuly
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 125, Iss , Pp 109951- (2020)
Envenomation by snakes is a worldwide health public issue, and antivenoms are less efficient in neutralizing local toxic effects. Thus, more efficient therapies to treat patients deserve attention, and plants have been extensively tested. So, the aim
Externí odkaz:
https://doaj.org/article/12d10fbe99d143c098f362f66aa9b510
Autor:
Ana Cláudia Rodrigues da Silva, Luciana Garcia Ferreira, Maria Eugênia Rabello Duarte, Miguel Daniel Noseda, Eladio Flores Sanchez, André Lopes Fuly
Publikováno v:
Marine Drugs, Vol 13, Iss 6, Pp 3761-3775 (2015)
In Brazil, snakebites are a public health problem and accidents caused by Lachesis muta have the highest mortality index. Envenomation by L. muta is characterized by systemic (hypotension, bleeding and renal failure) and local effects (necrosis, pain
Externí odkaz:
https://doaj.org/article/2926c7972ae84535a7307b6ffe98a477
Autor:
Thaisa Francielle Souza Domingos, Magui Aparecida Vallim, Diana Negrão Cavalcanti, Eládio Flores Sanchez, Valéria Laneuville Teixeira, André Lopes Fuly
Publikováno v:
Molecules, Vol 20, Iss 3, Pp 3515-3526 (2015)
Snake venoms are composed of a complex mixture of active proteins and peptides which induce a wide range of toxic effects. Envenomation by Bothrops jararaca venom results in hemorrhage, edema, pain, tissue necrosis and hemolysis. In this work, the ef
Externí odkaz:
https://doaj.org/article/3ef4edc56ff342699635ba421f3f560f