Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Andre Kamkin"'
Autor:
Nikola Hadzi-Petrushev, Radoslav Stojchevski, Anastasija Jakimovska, Mimoza Stamenkovska, Slavica Josifovska, Aleksandar Stamatoski, Iliyana Sazdova, Ramadan Sopi, Andre Kamkin, Hristo Gagov, Mitko Mladenov, Dimiter Avtanski
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-19 (2024)
Abstract Glucose transporter 5 (GLUT5) overexpression has gained increasing attention due to its profound implications for tumorigenesis. This manuscript provides a comprehensive overview of the key findings and implications associated with GLUT5 ove
Externí odkaz:
https://doaj.org/article/d0863cdc9a1143df9c927b7837c424a5
Autor:
Vadim Mitrokhin, Nikola Hadzi-Petrushev, Viktor Kazanski, Stanislav Schileyko, Olga Kamkina, Anastasija Rodina, Alexandra Zolotareva, Valentin Zolotarev, Andre Kamkin, Mitko Mladenov
Publikováno v:
Cells, Vol 13, Iss 12, p 1014 (2024)
This manuscript explores the intricate role of acetylcholine-activated inward rectifier potassium (KACh) channels in the pathogenesis of atrial fibrillation (AF), a common cardiac arrhythmia. It delves into the molecular and cellular mechanisms that
Externí odkaz:
https://doaj.org/article/e2ff3201a8f64c2989fd5aae796c2898
Autor:
Mitko Mladenov, Jane Bogdanov, Bogdan Bogdanov, Nikola Hadzi-Petrushev, Andre Kamkin, Radoslav Stojchevski, Dimiter Avtanski
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-16 (2022)
Abstract Curcumin is a polyphenolic compound derived from turmeric that has potential beneficial properties for cardiovascular and renal diseases and is relatively safe and inexpensive. However, the application of curcumin is rather problematic due t
Externí odkaz:
https://doaj.org/article/d57bba6f185144f1850b50f988e985b8
Autor:
Slavica Josifovska, Sasho Panov, Nikola Hadzi-Petrushev, Vadim Mitrokhin, Andre Kamkin, Radoslav Stojchevski, Dimiter Avtanski, Mitko Mladenov
Publikováno v:
Molecules, Vol 28, Iss 9, p 3734 (2023)
Tetrahydrocurcumin (THC) is a metabolite of curcumin (CUR). It shares many of CUR’s beneficial biological activities in addition to being more water-soluble, chemically stable, and bioavailable compared to CUR. However, its mechanisms of action hav
Externí odkaz:
https://doaj.org/article/694d11e3d01f496c8213194b32917306
Autor:
Mimoza Stamenkovska, Nikola Hadzi-Petrushev, Aleksandar Nikodinovski, Hristo Gagov, Natalija Atanasova-Panchevska, Vadim Mitrokhin, Andre Kamkin, Mitko Mladenov
Publikováno v:
International Journal of Food Properties, Vol 24, Iss 1, Pp 1510-1528 (2021)
Cardiovascular diseases are the leading cause of death in the world and scientists pay a lot of attention to identify and reveal the mechanisms of their occurrence. Recently, the attention of scientists is focused increasingly on plant derivatives, s
Externí odkaz:
https://doaj.org/article/96e85f16770b4ac3bed1a3c6589aaca7
Autor:
Mimoza Stamenkovska, Qendrim Thaçi, Nikola Hadzi‐Petrushev, Marija Angelovski, Jane Bogdanov, Shkëlzen Reçica, Islam Kryeziu, Hristo Gagov, Vadim Mitrokhin, Andre Kamkin, Rudolf Schubert, Mitko Mladenov, Ramadan B. Sopi
Publikováno v:
Physiological Reports, Vol 8, Iss 16, Pp n/a-n/a (2020)
Abstract Background This study was undertaken to test the hypothesis that the newly synthesized curcuminoids B2BrBC and C66 supplementation will overcome hyperoxia‐induced tracheal hyperreactivity and impairment of relaxation of tracheal smooth mus
Externí odkaz:
https://doaj.org/article/08bd8701b1fc4de6992b371cb941583b
Autor:
Vadim Mitrokhin, Mitko Mladenov, Lyubov Gorbacheva, Irina Babkina, Irina Lovchikova, Viktor Kazanski, Andre Kamkin
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 32, Iss 5, Pp 1338-1343 (2018)
In this study, we explored the effect of NO-induced changes in [Ca2+]i homeostasis in rat ventricular cardiomyocytes through variation in extracellular Ca2+ and application of SNAP (S-nitroso-N-acetyl-d,l-penicillamine) as an NO-donor. The Fura-2 sig
Externí odkaz:
https://doaj.org/article/1401f259823846d2b3bda06a1101810d
Publikováno v:
Toxicology Mechanisms and Methods. 33:1-17
Reactive oxygen species (ROS) and associated oxidative stress are the main contributors to pathophysiological changes following myocardial infarction (MI), which is the principal cause of death from cardiovascular disease. The glutathione (GSH)/gluta
Autor:
Andre Kamkin, Mitko Mladenov, Hristo Gagov, Natalija Atanasova-Panchevska, Aleksandar Nikodinovski, Mimoza Stamenkovska, Nikola Hadzi-Petrushev, V.M. Mitrokhin
Publikováno v:
International Journal of Food Properties, Vol 24, Iss 1, Pp 1510-1528 (2021)
Cardiovascular diseases are the leading cause of death in the world and scientists pay a lot of attention to identify and reveal the mechanisms of their occurrence. Recently, the attention of scientists is focused increasingly on plant derivatives, s
Autor:
Mitko Mladenov, Andre Kamkin, L. R. Gorbacheva, Nikola Hadzi-Petrushev, V.M. Mitrokhin, Nikita Vachrushev
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 128:234-240
The main objective of this study was to determine the primary intracellular signalling pathway affected by prolonged (2 hours) incubation in interleukin-2 (IL-2). Based on the inflammatory nature of IL-2, priority was given to the involvement of inhi