Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Andre Kajdacsy‐Balla"'
Carcinogenesis and Prognostic Utility of Arginine Methylation-Related Genes in Hepatocellular Cancer
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 9422-9430 (2023)
Protein arginine methylation is among the most important post-translational modifications and has been studied in cancers such as those of the lung and breast. However, comparatively less has been investigated regarding hepatocellular carcinoma, with
Externí odkaz:
https://doaj.org/article/c30a987a1a4b488386750dfaed2c0483
Autor:
Samuel Carbunaru, Zequn Sun, Cordero McCall, Bernice Ofori, Norma Marshall, Heidy Wang, Michael Abern, Li Liu, Courtney M. P. Hollowell, Roohollah Sharifi, Patricia Vidal, Andre Kajdacsy‐Balla, Marin Sekosan, Karen Ferrer, Shoujin Wu, Marlene Gallegos, Peter H. Gann, Daniel Moreira, Lisa K. Sharp, Carol E. Ferrans, Adam B. Murphy
Publikováno v:
Cancer Medicine, Vol 12, Iss 19, Pp 19690-19700 (2023)
Abstract Introduction The Oncotype Dx Genomic Prostate Score (GPS) is a 17‐gene relative expression assay that predicts adverse pathology at prostatectomy. We conducted a novel randomized controlled trial to assess the impact of GPS on urologist's
Externí odkaz:
https://doaj.org/article/aba0b4e7a01141cca43ac9245b7c9239
Autor:
Samuel Carbunaru, James Stinson, Rilwan Babajide, Courtney M. P. Hollowell, Ximing Yang, Marin Sekosan, Karen Ferrer, Andre Kajdacsy‐Balla, Josephine Abelleira, Maria Ruden, Patrice King‐Lee, Daniel P. Dalton, David D. Casalino, Rick A. Kittles, Peter H. Gann, Edward M. Schaeffer, Adam B. Murphy
Publikováno v:
BJUI Compass, Vol 2, Iss 6, Pp 370-376 (2021)
Abstract Objective To compare Prostate Health Index (PHI) and prostate‐specific antigen (PSA) density as secondary tests after multiparametric magnetic resonance imaging (mpMRI) in improving the detection accuracy of Gleason grade group (GG) 2‐5
Externí odkaz:
https://doaj.org/article/26a1353c71a044758901967680e4da82
Autor:
Zachary Richards, Tara McCray, Joseph Marsili, Morgan L. Zenner, Jacob T. Manlucu, Jason Garcia, Andre Kajdacsy-Balla, Marcus Murray, Cindy Voisine, Adam B. Murphy, Sarki A. Abdulkadir, Gail S. Prins, Larisa Nonn
Publikováno v:
iScience, Vol 12, Iss , Pp 304-317 (2019)
Summary: The fibromuscular stroma of the prostate regulates normal epithelial differentiation and contributes to carcinogenesis in vivo. We developed and characterized a human 3D prostate organoid co-culture model that incorporates prostate stroma. P
Externí odkaz:
https://doaj.org/article/a102fb12710c44299201cd66c7bc62a0
Publikováno v:
Cells, Vol 11, Iss 4, p 716 (2022)
The surgical pathology workflow currently adopted by clinics uses staining to reveal tissue architecture within thin sections. A trained pathologist then conducts a visual examination of these slices and, since the investigation is based on an empiri
Externí odkaz:
https://doaj.org/article/2d42db6e1315480d940a74f4d8a7b19d
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Breast cancer is the most common type of cancer among women worldwide. The standard histopathology of breast tissue, the primary means of disease diagnosis, involves manual microscopic examination of stained tissue by a pathologist. Because
Externí odkaz:
https://doaj.org/article/1ba3e942909a401280d138ff0f6924eb
Autor:
Darren J. Wozniak, Andre Kajdacsy-Balla, Virgilia Macias, Susan Ball-Kell, Morgan L. Zenner, Wenjun Bie, Angela L. Tyner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
PTEN is often lost in prostate cancer. In this study, the authors show that PTEN can act as a protein phosphatase that targets active PTK6, thereby regulating its oncogenic signaling in prostate cancer progression.
Externí odkaz:
https://doaj.org/article/18dc9ef9edce4840868fb91007225a76
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Current histopathological diagnosis involves human expert interpretation of stained images for diagnosis. This process is prone to inter-observer variability, often leading to low concordance rates amongst pathologists across many types of tissues. F
Externí odkaz:
https://doaj.org/article/dd4796b63c294c35905b69d6e3b6cf10
Autor:
Chenfei Hu, Melissa Santi, Oluwatobi Adelaja, Andre Kajdacsy-Balla, Gabriel Popescu, William Kobak
Publikováno v:
Frontiers in Physics, Vol 7 (2019)
We studied collagen fiber organization in tissue affected by pelvic organ prolapse (POP) and compared it to asymptomatic controls. Both the control and POP tissue biopsies were prepared and measured by a highly sensitive quantitative phase imaging (Q
Externí odkaz:
https://doaj.org/article/9aca48670c7a4f4e8271b473ff31eb41
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0205219 (2019)
Chemical hyperspectral imaging (HSI) data is naturally high dimensional and large. There are thus inherent manual trade-offs in acquisition time, and the quality of data. Minimum Noise Fraction (MNF) developed by Green et al. [1] has been extensively
Externí odkaz:
https://doaj.org/article/42278266b77244ccb2aaba709a1bacfa