Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Andre J. Ouellette"'
Autor:
Shunta Nakamura, Kiminori Nakamura, Yuki Yokoi, Yu Shimizu, Shuya Ohira, Mizu Hagiwara, Zihao Song, Li Gan, Tomoyasu Aizawa, Daigo Hashimoto, Takanori Teshima, Andre J. Ouellette, Tokiyoshi Ayabe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Nonalcoholic steatohepatitis (NASH) is a chronic liver disease characterized by fibrosis that develops from fatty liver. Disruption of intestinal microbiota homeostasis, dysbiosis, is associated with fibrosis development in NASH. An antimicr
Externí odkaz:
https://doaj.org/article/ad3288f42a2948a6ac84fd4142d11a39
Autor:
Mansour A. Dughbaj, Jordanna G. Jayne, A Young J. Park, Timothy J. Bensman, Marquerita Algorri, Andre J. Ouellette, Michael E. Selsted, Paul M. Beringer
Publikováno v:
Antibiotics, Vol 10, Iss 9, p 1043 (2021)
Vicious cycles of chronic airway obstruction, lung infections with Pseudomonas aeruginosa, and neutrophil-dominated inflammation contribute to morbidity and mortality in cystic fibrosis (CF) patients. Rhesus theta defensin-1 (RTD-1) is an antimicrobi
Externí odkaz:
https://doaj.org/article/f41e8ed08e9e4187b2214ab78cd6cc90
Autor:
Angela Song, Anne C. Conibear, Richard J. Clark, Andre J. Ouellette, K. Johan Rosengren, Thanh Huyen Phan
Publikováno v:
Peptide Science. 114
Autor:
Patti Tran, A. young Park, Michael E. Selsted, Anthony E. Cabebe, Justin B. Schaal, Dat Q. Tran, Virginia Basso, Diana Ngole, Andre J. Ouellette, Paul M. Beringer, Yoshihiro Eriguchi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Invasive candidiasis is an increasingly frequent cause of serious and often fatal infections in hospitalized and immunosuppressed patients. Mortality rates associated with these infections have risen sharply due to the emergence of multidrug resistan
p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair
Autor:
Patrick T. Fueger, Michael Kahn, Nobuo Kato, Sarah K. Highlander, Masaya Ono, Nyam Osor Chimge, Yusuke Higuchi, Andre J. Ouellette, Cu Nguyen, Keisuke Chosa, Elizabeth Melendez, David P. Lin, Yoshihiro Eriguchi, Xiaohui Hu, Keith Lai, Keane K Y Lai
Publikováno v:
Cancers, Vol 13, Iss 1288, p 1288 (2021)
Cancers
Volume 13
Issue 6
Cancers
Volume 13
Issue 6
Simple Summary Given their high degree of identity and even greater similarity at the amino acid level, Kat3 coactivators, CBP (Kat3A) and p300 (Kat3B), have long been considered redundant. We describe the generation of novel p300 S89A knock-in mice
Publikováno v:
Principles of Mucosal Immunology ISBN: 9781317212942
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b14fde824364538ffa62ead847e14f5c
https://doi.org/10.1201/9781317212942-4
https://doi.org/10.1201/9781317212942-4
Autor:
Preetha Anand, Silvia Cermelli, Zhihuan Li, Adam Kassan, Marta Bosch, Robilyn Sigua, Lan Huang, Andre J Ouellette, Albert Pol, Michael A Welte, Steven P Gross
Publikováno v:
eLife, Vol 1 (2012)
We previously discovered histones bound to cytosolic lipid droplets (LDs); here we show that this forms a cellular antibacterial defense system. Sequestered on droplets under normal conditions, in the presence of bacterial lipopolysaccharide (LPS) or
Externí odkaz:
https://doaj.org/article/26ce51c630d04c8c8664410488150acc
Autor:
Carl P. Blobel, Michael E. Selsted, Justin B. Schaal, Prasad Tongaonkar, Thorsten Maretzky, Patti Tran, Andre J. Ouellette, Dat Q. Tran
Publikováno v:
Journal of Biological Chemistry
Theta-defensins (θ-defensins) are macrocyclic peptides expressed exclusively in granulocytes and selected epithelia of Old World monkeys. They contribute to anti-pathogen host defense responses by directly killing a diverse range of microbes. Of not
Autor:
Michael E. Selsted, Timothy J Bensman, A. Young J. Park, Marquerita Algorri, Jordanna G. Jayne, Paul M. Beringer, Mansour A. Dughbaj, Andre J. Ouellette
Publikováno v:
Antibiotics, Vol 10, Iss 1043, p 1043 (2021)
Antibiotics
Volume 10
Issue 9
Antibiotics
Volume 10
Issue 9
Vicious cycles of chronic airway obstruction, lung infections with Pseudomonas aeruginosa, and neutrophil-dominated inflammation contribute to morbidity and mortality in cystic fibrosis (CF) patients. Rhesus theta defensin-1 (RTD-1) is an antimicrobi
Autor:
Prasad Tongaonkar, Dat Q. Tran, Pércio S. Gulko, Michael E. Selsted, Katie K. Trinh, Justin B. Schaal, Vasu Punj, Akshay Subramanian, Andre J. Ouellette, Teresina Laragione
Publikováno v:
Physiol Genomics
Rhesus theta defensin-1 (RTD-1), a macrocyclic immunomodulatory host defense peptide from Old World monkeys, is therapeutic in pristane-induced arthritis (PIA) in rats, a model of rheumatoid arthritis (RA). RNA-sequence (RNA-Seq) analysis was used to